A5101692287- Mind wandering and attention
- Health and Well-being Studies
- Neuroscience and Neuropharmacology Research
- Cancer, Lipids, and Metabolism
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- NF-κB Signaling Pathways
- Endoplasmic Reticulum Stress and Disease
- Creativity in Education and Neuroscience
- Neuroscience and Neural Engineering
- Memory Processes and Influences
- Categorization, perception, and language
- Bioactive natural compounds
- Ion channel regulation and function
- Heart Rate Variability and Autonomic Control
- Cancer, Hypoxia, and Metabolism
- Perfectionism, Procrastination, Anxiety Studies
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Neurobiology and Insect Physiology Research
- Ubiquitin and proteasome pathways
- Chronic Kidney Disease and Diabetes
- High Altitude and Hypoxia
- Cardiac Health and Mental Health
- Learning Styles and Cognitive Differences
Anhui University
2021-2024
Weatherford College
2024
Shaoxing University
2024
Capital Medical University
2015-2023
Beijing Anzhen Hospital
2015-2023
Central South University
2022
Toronto Metropolitan University
2021-2022
Hunan Cancer Hospital
2022
Guiyang Medical University
2016-2021
Affiliated Hospital of Guizhou Medical University
2016-2021
AimDespite the fact that angiotensin (Ang) II is a critical regulator of proliferation and migration vascular smooth muscle cells (VSMCs), effect Ang on VSMC has remained unclear. In this study, we determined whether Stim1- Orai1-mediated store-operated calcium (Ca2+) entry (SOCE) plays role in II-induced II-accelerated neointimal growth after balloon injury rat carotid arteries.
Abstract High altitude exposure increases the risk of myocardial ischemia (MI) and subsequent cardiovascular death. Machine learning techniques have been used to develop disease prediction models, but no reports exist for high induced ischemia. Our objective was establish a machine learning-based MI model identify key factors. Using prospective cohort study, predictive developed validated high-altitude MI. We consolidated health examination self-reported electronic questionnaire data...
The neurological correlates of Generalised Anxiety Disorder (GAD) are not well known, however there is evidence cortical dysregulation in patients with GAD. aim the study was to examine functional activity different cerebral regions GAD using electroencephalogram (EEG) nonlinear analysis evaluate its contribution anxiety severity.The cohorts consisted 64 diagnosed as classified by Structured Clinical Interview for Diagnostic and Statistical Manual American Psychiatric Association-IV-TR....
Background: Endoplasmic reticulum stress (ERS) has been recently suggested to be activated in the major depressive disorder (MDD). However, whether ERS is a potential therapeutic target for MDD largely unknown. Here we attempted assess preventive effect of metoprolol (MET), N-acetylcysteine (NAC), and escitalopram (ESC) on chronic unpredictable mild (CUMS)-induced depression investigate mediates antidepressant role these drugs. Method: Forty-five sprague-dawley rats were randomly divided...
There is evidence that atypical antipsychotics (APs) increase risk of osteoporosis in schizophrenia patients, however the mechanism unclear. The aim study was to explore molecular mechanisms about Wnt/β-catenin signal pathway underlying osteal side effects APs. We cultured human osteoblast cell line hFob1. 19 (OB) treatments with olanzapine, risperidone, amisulpride, aripiprazole or resveratrol vitro. OB cells viability detected by assay. apoptosis analyzed flow cytometry (FCM). Further...
PKC plays a critical role in competitive activity-dependent synapse modification at the neuromuscular vitro and vivo . This action involves reduction of strength inactive inputs to muscle cells that are activated by other inputs. A decrease postsynaptic responsiveness loss acetyl choline receptors account for heterosynaptic The is not seen preparations which has been blocked pharmacologically. Here, we show does occur made from animals genetically modified lack theta isoform PKC. Synapse...
Background. Insulin resistance (IR) is the main etiology of type 2 diabetes mellitus (T2DM). It has been known that total flavonoid extracts can markedly improve hypoglycemic symptoms caused by IR. Nevertheless, relevant molecular mechanism remains unclarified. Aim. This study aimed to investigate antihyperglycemic effects and extract from Oxytropis falcata Bunge. Methods. STZ-induced T2DM rats (n = 35) were divided into 5 groups: model, low-, medium-, high-dose flavonoids, pioglitazone...
We assessed the influence of insulin resistance (IR) on development contrast-induced nephropathy (CIN) in patients (n = 719) undergoing elective percutaneous coronary intervention (PCI). Patients were divided into diabetes mellitus (DM 242), nondiabetic IR (IR 120), and sensitivity (IS 357) groups according to medical history homeostasis model assessment index. Serum creatinine (SCr) estimated glomerular filtration rate (eGFR) measured before 72 hours after PCI. There no differences SCr eGFR...
Long noncoding RNAs (lncRNAs) are related to the development and treatment of neuroblastoma. The lncRNA LINC00839 is dysregulated in neuroblastoma, while its function mechanism neuroblastoma remain largely unclear.The tumor adjacent noncancerous tissues were collected from 48 patients. LINC00839, glucose transporter 1 (GLUT1) microRNA-338-3p (miR-338-3p) abundances examined via quantitative reverse transcription polymerase chain reaction or Western blot. Cell proliferation, apoptosis,...
Cancer cells prefer glycolysis to support their proliferation. Our previous studies have shown that the long palate, lung, and nasal epithelial cell clone 1 (LPLUNC1) can upregulate prohibitin (PHB1) expression inhibit proliferation of nasopharyngeal carcinoma (NPC) cells. Given PHB1 is an important regulator energy metabolism, we explored whether how LPLUNC1 regulated glucose in NPC or overexpression decreased increased oxidative phosphorylation (OXPHOS)-related protein cells, promoting...
This aim of this study was to assess the molecular mechanism osteoporosis in schizophrenia patients with risperidone use. Here, we investigated effects on cellular proliferation and apoptosis a preosteoblast cell line, MC3T3-E1. Cell viability apoptotic rate MC3T3-E1 were detected by counting kit-8 flow cytometry at serial dose different time points, respectively. Bone transformation relevant gene serum osteocalcin (BGP), collagen 1, tumor necrosis factor-α (TNF-α), osteoprotegerin (OPG),...
Background: Major depressive disorder (MDD) was reported to be associated with endoplasmic reticulum stress (ERS) combined oxidative (OS) (ERS/OS). Here, we aimed investigate the effects of escitalopram (ESC) on blood-brain barrier (BBB) permeability and ERS/OS-related pathways in brain microvascular endothelial cells (bEnd.3 cells) induced by tunicamycin (TM). Methods: bEnd.3 were divided into four groups: control, TM, ESC, ESC + TM groups. CCK-8 flow cytometry used detect cell survival...
We have used a three compartment tissue culture system that involved two separate populations of cholinergic neurons in the side compartments converged on common target population myotubes center compartment. Activation axons from one produced selective down-regulation synaptic inputs other neuronal (when innervated same myotubes). The decrease heterosynaptic was mediated by protein kinase C (PKC). An activity-dependent action A (PKA) associated with stimulated input and this served to...
To explore the function of Tangnaikang (TNK) in prevention and treatment renal interstitial fibrosis through transdifferentiation human tubular epithelial cell line HK-2 induced by transforming growth factor-beta1 (TGF-beta1).HK-2 cells cultured dulbecco's modified eagle medium/F12 (1 : 1) with 10% fetal calf serum were divided into six groups: blank control group, TGF-beta1 group (TGF-beta1 10 ng/mL), ng/mL + serum), 1 5% TNK 2 3 20% serum). Cell proliferation was detected...
<p>Objectives: The aim of this study is to examine the long-term maintenance training benefits in inhibition, as measured with Stroop task, older adults over 1- and 3-year periods. Methods: Participants from an original 6-session (Wilkinson & Yang, 2012 [Wilkinson, A. J., L. (2012). Plasticity inhibition adults: Retest practice transfer effects. Psychology Aging, 27, 606–615. doi:10.1037/a0025926]) were invited come back lab complete a single session task at 2 different time...
<p>Objectives: The aim of this study is to examine the long-term maintenance training benefits in inhibition, as measured with Stroop task, older adults over 1- and 3-year periods. Methods: Participants from an original 6-session (Wilkinson & Yang, 2012 [Wilkinson, A. J., L. (2012). Plasticity inhibition adults: Retest practice transfer effects. Psychology Aging, 27, 606–615. doi:10.1037/a0025926]) were invited come back lab complete a single session task at 2 different time...
We investigated retest learning (i.e., performance improvement through practice) in the absence of itemspecific effects memorizing or becoming familiar with specific items) older adults. Thirty-one adults (ages 60 – 82 years, M = 71.10, SD 6.27) participated an eight-session self-guided program. To eliminate item-specific effects, parallel versions representative psychometric measures for Inductive Reasoning, Perceptual Speed, and Visual Attention were developed administered across sessions....
We investigated retest learning (i.e., performance improvement through practice) in the absence of itemspecific effects memorizing or becoming familiar with specific items) older adults. Thirty-one adults (ages 60 – 82 years, M = 71.10, SD 6.27) participated an eight-session self-guided program. To eliminate item-specific effects, parallel versions representative psychometric measures for Inductive Reasoning, Perceptual Speed, and Visual Attention were developed administered across sessions....
Klippel-Trenaunay syndrome (KTS) is a rare congenital venous malformation, it had been found to be caused by mutations of the phosphatidylinositol 4, 5-diphosphate 3-kinase catalytic subunit alpha (PIK3CA) gene. Currently KTS defined as triad skin wine pigmented spots, varicose veins and malformations lower extremities, hypertrophy bone soft tissue, involving urinary system up 6% 30%. When involved, often presented painless massive gross hematuria.
Football reform and development have attracted much attention. For this reason, relevant units issued policies activity guidelines for preschool football to clarify the construction of kindergarten football. The stage young children from 3 6 years old is key period children's sports interests, habits, cognition skills. Therefore, perspective enlightenment football, paper analyzes following problems in football: insufficient support government social forces; Kindergarten facilities...