A5046982461- Hydrocarbon exploration and reservoir analysis
- Hydraulic Fracturing and Reservoir Analysis
- Cancer-related molecular mechanisms research
- Gastrointestinal motility and disorders
- Geological Studies and Exploration
- Neuroscience and Music Perception
- Antibiotic Resistance in Bacteria
- Ferroptosis and cancer prognosis
- Geological and Geophysical Studies
- Functional Brain Connectivity Studies
- Helicobacter pylori-related gastroenterology studies
- RNA modifications and cancer
- Infections and bacterial resistance
- NMR spectroscopy and applications
- Innovations in Medical Education
- Music Therapy and Health
- Intracranial Aneurysms: Treatment and Complications
- Cancer, Lipids, and Metabolism
- Bacteriophages and microbial interactions
- Higher Education Learning Practices
- Gastrointestinal disorders and treatments
- Empathy and Medical Education
- Geochemistry and Elemental Analysis
- Bacterial biofilms and quorum sensing
- Mycobacterium research and diagnosis
China University of Petroleum, Beijing
2021-2024
University of Calgary
2023-2024
Affiliated Hospital of Hangzhou Normal University
2010-2023
Nanjing Tech University
2022-2023
Zhujiang Hospital
2015
Southern Medical University
2015
Hangzhou Normal University
2009-2013
Lishui Central Hospital
2009-2012
Zhongshan Hospital
2012
Second Affiliated Hospital of Zhejiang University
2011
AIM:To establish an accurate and rapid stem-loop reverse transcriptional real-time PCR (RT-PCR) method to quantify human let-7a miRNA in gastric cancer. METHODS:According the sequence of miRNA, primer, primers quantitative MGB probes were designed synthesized.The dynamic range sensitivity determined.The levels examined 32 carcinoma samples by RT-PCR method. RESULTS:The quantification scheme evaluated, result showed assay could precisely detect 10 copies mature as few 0.05 ng total RNA...
Abstract 5-Fluorouracil (5-FU) is known as a first-line chemotherapeutic agent against colorectal cancer (CRC), but drug resistance occurs frequently and significantly limits its clinical success. Our previous study showed that the protocadherin 17 ( PCDH17 ) gene was methylated functioned tumor suppressor in CRC. However, relationship between 5-FU CRC remains unclear. Here, we revealed more highly expressed 5-FU-sensitive tissues than 5-FU-resistant tissues, high expression of correlated...
Background and Purpose The appearance aggravation of diarrhea-predominant irritable bowel syndrome (IBS-D) have proven to be closely related psychosocial factors. We aimed measure altered spontaneous brain activity functional connectivity (FC) in patients with IBS-D using resting-state magnetic resonance imaging (RS-fMRI) analyze the relationship between these parameters emotional symptoms. Methods Thirty-six adult thirty-six demographic-matched healthy controls (HCs) underwent RS-fMRI...
Low and ultra‐low permeability reservoirs are widely developed in the Upper Triassic Yanchang Formation Ordos Basin, its intricate pore throat structure has a significant impact on physical properties heterogeneity of reservoirs. This paper conducted series experiments to investigate petrology, structure, fractal characteristics sandstone reservoirs, influencing factors properties. The results show sixth member (Chang 6) reservoir Xiaojiahe area is dominated by feldspathic sandstone. main...
Aortoesophageal fistula (AEF) is a rare but life-threatening cause of upper gastrointestinal bleeding. Only handful cases successful management AEF caused by esophageal cancer have been reported. The purpose this study to report case managed endovascular aortic repair and review the relevant literature.A 66-year-old man with gastroenterology bleeding presented at Emergency Department our hospital complaining chest pain, fever hematemesis for 6 h. He had vomited 400 mL bright-red blood...
Depressive symptom is one of the most common symptoms in patients with irritable bowel syndrome (IBS), but its pathogenetic mechanisms remain unclear. As a voxel-level graph theory analysis method, degree centrality (DC) can provide new perspective for exploring abnormalities whole-brain functional network IBS depressive (DEP-IBS).DC, voxel-wise image and clinical correlation seed-based connectivity (FC) analyses were performed 28 DEP-IBS patients, 21 without (nDEP-IBS) 36 matched healthy...
Escherichia coli biofilm may form naturally on biotic and abiotic surfaces; this represents a promising approach for efficient biochemical production in industrial fermentation. Recently, exploitation of the advantages optogenetics, such as simple operation, high spatiotemporal control, programmability, regulation formation has garnered considerable attention. In study, we used blue light signaling-induced optogenetic system Magnet an E. biofilm-based immobilized fermentation to produce...
The aim of this study was to detect novel variants the Stenotrophomonas maltophilia Smqnr gene family and analyse prevalence genes in clinical isolates S. China. In total, 442 were collected from nine hospitals four provinces Antimicrobial susceptibility testing against six commonly used antibiotics performed on these isolates. sequences amplified by PCR aligned with those known GenBank an database. resistance rate co-trimoxazole highest at 48.6 %, followed rates ceftazidime,...
Basic leucine zipper and W2 domain 2 (BZW2), also known as 5MP1, is a protein related to translation regulation.Evidence from previous studies indicates that BZW2 involved in tumorigenesis several cancers.However, little about the role of hepatocellular carcinoma (HCC).In this study, we first analyzed gene expression profile multiple HCC datasets.Next, explored biological effects cell lines.BZW2 was overexpressed different cohorts.Multivariate analysis confirmed increased an independent...
The unclear understanding of the source rock characteristics for Paleogene Dongying Formation in Bozhong Sag leads to lack cognition oil and gas exploration. This research systematically evaluated discrepancy geochemical intervals based on detailed analysis using Rock‐Eval pyrolysis, total organic carbon (TOC), vitrinite reflectance ( R o ), maceral components, stable isotopes biomarker parameters. It discusses matter sources, depositional environment, thermal maturity hydrocarbon generation...
One highly multi-drug-resistant, mucus-producing and foul-smelling strain of Klebsiella ozaenae was isolated from a patient in the ICU Chinese tertiary hospital. MICs several clinical antimicrobials against were obtained using Vitek-2 Compact System with AST-GN13 cards resistance genes evaluated by PCR gene sequencing. The resistant to most β-lactams quinolones tested carried antibiotic genes, including bla(KPC-2), bla(TEM-98), bla(CTX-M-3), bla(SHV-26) qnrS. To our knowledge, this is first...
AdeABC efflux pump in a total of 50 Acinetobacter baumannii strains were investigated and the role contributing to hydrolysis carbapenems further analyzed. All strains divided into 3 groups according their susceptibilities Imipenem, Amikacin, Minocycline Levofloxacin: Group A (22 imipenem-resistant strains), B (13 isolates which imipenem-sensitive but resistant at least one other three antibiotics) C (15 isolates, sensitive all antimicrobials). Five gene types observed REP-PCR 39 included...