- Chalcogenide Semiconductor Thin Films
- Copper-based nanomaterials and applications
- Orthopaedic implants and arthroplasty
- Quantum Dots Synthesis And Properties
- Neonatal and Maternal Infections
- Neonatal Respiratory Health Research
- Bone fractures and treatments
- TiO2 Photocatalysis and Solar Cells
- Orthopedic Surgery and Rehabilitation
- Hepatitis C virus research
- Pancreatitis Pathology and Treatment
- Eosinophilic Disorders and Syndromes
- Infant Nutrition and Health
- IgG4-Related and Inflammatory Diseases
- Liver Diseases and Immunity
- Language Development and Disorders
- Wnt/β-catenin signaling in development and cancer
- Risk and Safety Analysis
- Aerosol Filtration and Electrostatic Precipitation
- Monoclonal and Polyclonal Antibodies Research
- Cutaneous lymphoproliferative disorders research
- Veterinary Orthopedics and Neurology
- Silicone and Siloxane Chemistry
- Advanced Glycation End Products research
- Reproductive tract infections research
Heinrich Heine University Düsseldorf
2024
Ludwig-Maximilians-Universität München
2024
Deutsches Diabetes-Zentrum e.V.
2024
German Center for Diabetes Research
2024
Charité - Universitätsmedizin Berlin
2004-2024
Kantonsspital Graubünden
2012-2022
LVR-Klinik Bonn
2021
Leibniz-Institute for New Materials
2005-2018
Centre Hospitalier Universitaire de Martinique
2016
Leibniz Association
2013-2014
Background: It was the aim of this study to assess whether very-low-birth-weight (VLBW) infants born small for gestational age (SGA; birth weight less than 10th percentile) are at increased risk late-onset sepsis. Methods: This a prospective, multicenter German Neonatal Network including VLBW from 23 < 32 weeks post menstrual 2009–2011. Outcomes were compared between SGA (birth tenth percentile according and gender) non-SGA infants. The main outcome measure least 1 episode sepsis defined as...
We have studied the distribution of thoracic somite and somitocoele-derived cells using homotopical grafting between quail chicken embryos rein-cubation periods 2-6 days. Serial sections were evaluated with antibodies against cells, hemangiopoietic desmin. With exception neural crest in cranial sclerotome half, all operated segment are derived from a <i>single somite</i>. These differentiate into sclerotome, myotome anlage dermis back. After longer re-incubation periods,...
Intrauterine growth restriction (IUGR) is a well-known cause of adverse neonatal outcomes. As it may have an impact on innate immune responses, we aimed to investigate several parameters the response in preterm infants ≤32 weeks gestation who were small for gestational age (SGA).We compared clinical data SGA (n = 20) and appropriate (AGA; n 124) newborns with weeks. We investigated full blood counts at birth days 3 7 life cytokine responses human whole cord assay.SGA had higher risk combined...
Mepolizumab was originally intended as a therapeutic agent for atopic asthma in adults, and consequently, little is known about its use children. Up to now, corticosteroids have formed the basis of initial treatment hypereosinophilic syndromes are shown be effective most patients. To analyze effect mepolizumab children aim this study.We reporting experience 2 pediatric patients with syndrome that not sufficiently controlled by other drugs. In addition, literature regarding adult reviewed...
The success of artificial reproductive techniques not only depends on the quality oocytes and spermatozoa but also receptivity endometrium. aim this study was to assess role endometrial volume measurement by three-dimensional ultrasound in predicting pregnancy rate (PR) women receiving controlled ovarian hyperstimulation followed intrauterine insemination.104 patients having insemination (IUI) were included prospective trial. Ovarian performed with gonadotropins 73 % clomiphene citrate (CC)...
Gamma delta (γδ) T cells represent a minor fraction of human cell repertoire but play an important role in mediating anti-infectious and anti-tumorous effects the context allogeneic hematopoietic stem transplantation (allo-HSCT). We performed prospective study to analyze effect different transplant modalities on immune reconstitution γδ subsets. CD3, CD4 CD8 were analyzed parallel. Secondly, we examined impact clinical outcomes including acute Graft-versus-Host-Disease (aGvHD) viral...
Infiltration of adipocytes into the pancreatic parenchyma has been linked to impaired insulin secretion in individuals with increased genetic risk T2D and prediabetic conditions. However, study this ectopic fat depot limited by lack suitable vitro models. Here, we developed a novel 3D model functionally mature human adipose tissue organoids aggregating tissue-derived stromal vascular fraction (SVF) cells differentiating them over 19 days. These carry biological properties situ fat,...
Einleitung: Strahlverfahren werden bei den unterschiedlichsten Prozessen zur Oberflächenbearbeitung von Hüftimplantaten verwendet. Mit Edelkorund (Al2O3) rau gestrahlte Titanoberflächen in der zementfreien Hüftendoprothetik führen zu einer besseren knöchernen Integration. Publikationen aus Zahnheilkunde und Orthopädie belegen, dass mit Restpartikel auf Oberfläche des bearbeiteten Implantates verbleiben. Es existiert bisher keine Studie, die Oberflächen Hinblick Reinigung Al2O3-...
Abstract Der Ausbau von Verkehrswegen gehört zu den ingenieurtechnischen Aufgaben, welche die erforderliche Leistungsfähigkeit unserer verkehrlichen Infrastruktur sicherstellen. Am Beispiel der Abdeckelung Autobahn A59 im innerstädtischen Bereich Duisburg wird gezeigt, wie durch eine besonders auf bauliche Umsetzung ausgerichtete Planung mit Entwicklung maßgebender Detailpunkte Herstellung erfolgen konnte, sich bezüglich Bauablauf und Zeitaufwand als optimiert ergeben hat, wirtschaftliche...
Einleitung: Die erst in den letzten Jahren beschriebene IgG4-assoziierte Cholangitis (IAC) wird aufgrund ihres aggressiveren Verlaufs und Ansprechens auf Kortikosteroide von der „klassischen“ PSC mit normalen IgG4 Konzentrationen abgegrenzt. Prävalenz erhöhter bei anderen chronischen Lebererkrankungen wurde dagegen bisher nicht untersucht.
Einleitung: PSC-Patienten mit erhöhten IgG4 Serumspiegeln (PSC-IgG4+) zeigen nach neueren US- amerikanischen Studien einen aggressiveren Verlauf als Patienten „klassischer“ PSC ohne erhöhte Serumspiegel. Vergleichbare europäische Daten existieren bisher nicht.