A5100757589- Balance, Gait, and Falls Prevention
- Stroke Rehabilitation and Recovery
- Atherosclerosis and Cardiovascular Diseases
- Cerebral Palsy and Movement Disorders
- Peptidase Inhibition and Analysis
- Lipoproteins and Cardiovascular Health
- Diabetes Treatment and Management
- Cardiovascular Health and Disease Prevention
- Spine and Intervertebral Disc Pathology
- CNS Lymphoma Diagnosis and Treatment
- Natural Products and Biological Research
- Probability and Risk Models
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Cardiac Imaging and Diagnostics
- Diabetes Management and Research
- Acupuncture Treatment Research Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Oral microbiology and periodontitis research
- Cardiac Arrest and Resuscitation
- Growth Hormone and Insulin-like Growth Factors
- Spinal Hematomas and Complications
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Older Adults Driving Studies
- Acute Myocardial Infarction Research
University of Science and Technology of China
2022-2025
Chinese PLA General Hospital
2014-2025
Shanghai Jiao Tong University
2024
Shanghai First People's Hospital
2024
Soochow University
2022
First Affiliated Hospital of Jinan University
2020
Background: Disruption of circadian rest-activity rhythm (RAR) has been found in many neurological disorders. Objective: In this study, actigraphic data were collected and analyzed to identify the RAR pattern elderly with cerebral small vessel disease. Methods: 115 disease (CSVD) cases recruited. The presence lacune infarct, white matter hyperintensities, microbleeds magnetic resonance imaging (MRI) images rated independently, as well using a simple MRI score 0–3 points. Each subject wore an...
Concerning the related factors for kidney disease and high chronic (CKD) progression risk, there is still a lack of study in adult-onset type 1 diabetes mellitus (T1DM) patients from China. Four hundred eighty-one T1DM Guangdong translational medicine were included. Logistic regression analysis (Forward: LR) was utilized to identify glycemic- nonglycemic-related associated with moderate albuminuria, severe mildly reduced estimated glomerular filtration rate (eGFR), decreased eGFR, CKD...
Abstract Early insulin therapy is capable to achieve glycemic control and restore β-cell function in newly diagnosed type 2 diabetes (T2D), but its effect on cardiovascular outcomes these patients remains unclear. In this nationwide real-world study, we analyzed electronic health record data from 19 medical centers across China between 1 January 2000, 26 May 2022. We included 5424 eligible (mean age 56 years, 2176 women/3248 men) who were T2D within six months did not have prior disease....
Osteoporotic women exhibit high frequency of alveolar bone loss and low density. Estrogen deficiency, which is vital in the pathogenesis postmenopausal osteoporosis, has received increasing attention studies related to periodontal diseases. Similar most hormones, estrogen exerts its influence by binding specific receptors, receptor (ER)-alpha -beta. The ligament cells (PDLcs) are very important maintaining integrity tissue, connective tissue located between root surface tooth. In this study,...
To analyze the pathogen distribution and drug resistance of newborns with bloodstream infection (BSI) to help clinicians choose appropriate empirical antibiotic therapy for clinical control.
Electronic nicotine delivery systems (ENDS) may improve public health if they facilitate smokers switching away from cigarettes. Conceptually, is facilitated when ENDS provide adequate delivery. Switching rates among who purchased the JUUL System ("JUUL") were compared in United Kingdom (UK), where regulations limit concentration to 20 mg/mL versus North America (N.Am.; States and Canada), higher concentrations are available.Adult established (age ≥21, smoked ≥100 cigarettes, smoking some...
Abstract Abnormal cardiac fibrosis is the main pathological change of post-myocardial infarction (MI) heart failure. Although E3 ubiquitin ligase FBXL8 a key regulator in cell cycle, proliferation, and inflammation, its role post-MI ventricular failure remains unknown. was primarily expressed fibroblasts (CFs) remarkably decreased CFs treated by TGFβ subjected to MI. The echocardiography histology data suggested that adeno-associated viruses (AAV9)-mediated overexpression had improved...
Objective To determine the multiple functions of policosanol in elderly dyslipidemia patients. Methodology: There were 294 patients enrolled into this clinical study. They randomly divided four groups, as follows: 20 mg (group A, n = 64); 10 B, 72); atorvastatin C, 91); and + D, 62). Plasma platelet count, aggregation rate, circulating endothelial cell (CEC) high sensitivity C-reactive protein (hs-CRP), carotid intima–media thickness (IMT) measured before study (week 0) at weeks 12, 24, 52....
To observe the effect of acupotomy on fat infiltration degree lumbar multifidus muscle (LMM) in patients with disc herniation after percutaneous transforaminal endoscopic discectomy (PTED).A total 104 treated PTED were randomly divided into an observation group (52 cases, 3 cases dropped off) and a control 4 off). Patients both groups received rehabilitation training two weeks 48 h treatment. The was (L3-L5 Jiaji [EX-B 2]) once within 24 PTED. In groups, cross sectional area (CSA) LMM...
Objective This study was performed to evaluate the association between urinary sodium excretion and coronary heart disease (CHD) in hospitalized elderly patients China. Methods The 24-h specimens of 541 were collected, serum creatinine concentration sodium/potassium ratio measured. Associations explored by multivariate logistic regression analysis. Results mean 200.4 mmol, corresponding 11.7 g salt intake. Both these values higher men than women. intake 80- 89-year-old significantly lower...
We aimed to explore the effects of lipid smoothness on progression and vulnerability atherosclerotic plaques.24 rabbits were divided into three groups randomly. Group 1 was given standard chow diet; group 2 fed with cholesterol-rich for 3, subjects planned take diet at first phase 12 weeks during second phase, low-fat then applied alternately every till end experiment. Lipid profiles, inflammatory factors, endothelium functions, pathological histological changes examined. Expressions matrix...
Gait impairment is a common symptom among individuals with cerebral small vessel disease (CSVD). However, performance differences between single-task walking (STW) and dual-task (DTW) CSVD remain unclear. Therefore, we aimed to examine in gait characteristics during STW DTW as well the association neuroimaging markers.We enrolled 126 older CSVD. The speed, cadence, stride length, time, their cost (DTC) or variability were measured under STW, motor-cognitive (cognitive DTW), motor-motor...
ObjectiveWe aimed to (1) identify neuroimaging biomarkers of distinguishing motoric cognitive risk syndrome (MCRS) among older Chinese adults with cerebral small vessel disease (CSVD) and (2) detect differences in gait parameters between CSVD individual without MCRS, especially during dual-task walking (DTW).MethodsWe enrolled 126 inpatients who were divided into two groups according MCRS status. Data on basic parameters, variability, asymmetry, coordination collected single-task (STW) DTW....
Key Clinical Message Prompt and precise diagnosis of pituitary hyperplasia secondary to primary hypothyroidism (PHPH) is crucial avoid unwarranted surgery potential permanent impairment. Although PHPH may present similarly adenoma, it responsive thyroxine therapy, underscoring the critical role differential in treatment adolescent patients.
This study aimed to investigate the protective effect of Xinmailong injection on rats with myocardial infarction. Thirty-six were induced infarction by operation, and six underwent sham operation. The randomly divided into three groups, 12 in each, administered intraperitoneal 5 mg/(kg·d), sodium creatine phosphate 80 or normal saline as control respectively for 14 days. When treatments completed, hemodynamic parameters observed, blood samples taken examine routine, coagulation index, liver...
Elderly patients receiving nasal feeding have weaker physiological function, and placement of a nasogastric tube weakens the natural barrier cardia-esophageal sphincter; therefore, risk gastroesophageal reflux (GER) is higher. Many studies shown that pepsin extremely sensitive in predicting GERD, so this study intends to investigate level saliva elderly with analyze its influencing factors.This was cross-sectional study. Patients admitted Chinese PLA General Hospital from April 2018 October...
Objective: We aimed to (1) identify neuroimaging biomarkers of motoric cognitive risk syndrome (MCRS) among older Chinese adults with cerebral small vessel disease (CSVD) and (2) detect differences in gait parameters between CSVD individual without MCRS, especially during dual-task walking (DTW). Methods: enrolled 126 inpatients who were divided into two groups according MCRS status. Data on basic parameters, variability, asymmetry, coordination collected single-task (STW) DTW. Neuroimaging...
This study aims to explore the correlation between body composition, encompassing factors such as muscle mass and fat distribution, gait performance during both single-task walking (STW) dual-task (DTW) in patients diagnosed with cerebral small vessel disease (CSVD).
We consider the problem of Gaussian approximation for $\kappa$th coordinate a sum high-dimensional random vectors. Such has been studied previously $\kappa=1$ (i.e., maxima). However, in many applications, general $\kappa\geq1$ is great interest, which addressed this paper. make four contributions: 1) we first show that distribution vectors, $\boldsymbol{X}= (X_{1},\cdots,X_{p})^{\sf T}= n^{-1/2}\sum_{i=1}^n \boldsymbol{x}_{i}$, can be approximated by vectors and derive their Kolmogorov's...
To evaluate the effects of blood lipid stability on progression carotid atherosclerosis.A total 416 patients who had physical examination in our hospital annually from January 2010 to December 2015 were selected and divided into a group (n=216) non-progression (n=200) according intima-media thickness measured by ultrasound. The levels lipid-related parameters within five years retrospectively analyzed calculate smoothness index (SI = x±/s).The cross-sectional TG, HDL-C, ApoAI, ApoB, ApoE Lpa...