- Migraine and Headache Studies
- Ocular Surface and Contact Lens
- Advanced Drug Delivery Systems
- Retinal Imaging and Analysis
- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Retinal and Optic Conditions
- Photocathodes and Microchannel Plates
- Bone Tissue Engineering Materials
- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
- Orthopedic Infections and Treatments
- Protease and Inhibitor Mechanisms
- Child Abuse and Related Trauma
- Blasting Impact and Analysis
- Pregnancy and Medication Impact
- Sodium Intake and Health
- TGF-β signaling in diseases
- Cardiac and Coronary Surgery Techniques
- Drug Solubulity and Delivery Systems
- Therapeutic Uses of Natural Elements
- Clinical Nutrition and Gastroenterology
- Pelvic floor disorders treatments
- Polymer Surface Interaction Studies
Third Affiliated Hospital of Sun Yat-sen University
2022-2024
Sun Yat-sen University
2022-2024
Jiangsu University
2024
Chinese PLA General Hospital
2010-2022
Guangzhou Women and Children Medical Center
2015-2022
Guangzhou Medical University
2015-2022
Tianjin Chest Hospital
2021-2022
National Center for Nanoscience and Technology
2021
Tianjin University of Traditional Chinese Medicine
2021
Chinese People's Liberation Army
2020
An alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy bone regeneration.
Clinical and basic research increasingly suggests a correlation between migraine irritable bowel syndrome (IBS). In this study, we aimed to explore the clinical features risk factors for IBS in patients.This was retrospective, cross-sectional study. A total of 1,112 consecutive patients from internal medicine emergency departments three hospitals June 2014 through 2016. comprehensive interviewer-administered questionnaire designed based on International Classification Headache Disorders, 3rd...
This study was conducted to determine blood flow velocities and corresponding vessel diameters characterize the response of bulbar conjunctival microvasculature contact lens wear.A functional slit-lamp biomicroscope (FSLB), an adapted traditional slitlamp, used image temporal conjunctiva 22 healthy subjects before after 6 hr wear. All measurable venules on were processed yield velocities.The average velocity increased from 0.51±0.20 0.65±0.22 mm/sec (P<0.001) The distribution showed a...
Abstract Background To date, there have been very few studies that explored the relationship between headaches and computer use. The chief aim of this study is to investigate prevalence primary headache disorders among informational technology staff identify potential factors contributing it. Methods This a cross-sectional based on annual health checks employees from information industry. We identified 2216 members Beijing by stratified random sampling who met inclusion criteria. All...
To investigate the tight junction protein expressions of intestinal mucosa in an experimental model cardiopulmonary bypass (CPB) rats.Thirty anesthetized rats were randomly divided into two groups: Group S (n = 10) served as sham operation and group C 20) CPB which underwent for 1 h. Expression occludin zonula occludens-1 (ZO-1) determined by Western blotting immunotochemistry, respectively. Plasma levels diamine oxidase (DAO) d-lactate using enzymatic spectrophotometry.Immunohistochemical...
Abstract Thermo-sensitive hydrogel has attracted considerable attention as a kind of intelligent material in the field biochemistry and biomedicine. They have many kinds advantages such easy formulation to deliver hydrophilic hydrophobic drugs, high drug loading capacity, convenient administration, sustained release target specificity by using injections thereby avoiding need surgery. Besides, thermo-sensitive an increasing concern for its behavior, biocompatibility, biodegradability. The...
Objective This study was performed to evaluate the association between urinary sodium excretion and coronary heart disease (CHD) in hospitalized elderly patients China. Methods The 24-h specimens of 541 were collected, serum creatinine concentration sodium/potassium ratio measured. Associations explored by multivariate logistic regression analysis. Results mean 200.4 mmol, corresponding 11.7 g salt intake. Both these values higher men than women. intake 80- 89-year-old significantly lower...
Recent advances in self-assembled nanogel carriers have allowed precise design of hierarchical structures by a low-cost solution-phase approach. Typically, photochemical strategy on the tailor morphology and dimension has emerged as powerful tool, because light-trigger exceptional advantages an instant "on/off" function spatiotemporal precision at arbitrary time. Herein, we report tunable manipulation sequentially morphological transition via "living" thiol-disulfide exchange reaction from...
By observing the effect of N-acetylcysteine (NAC) on proliferation and collagen synthesis rat cardiac fibroblasts (CFs) to explore NAC remodeling (CR).In vivo, first, Sprague Dawley (SD) myocardial hypertrophy model was constructed, structure function detected by echocardiography, serological testing, Masson staining. Western blotting (WB) quantitative real-time polymerase chain reaction (qRT-PCR) were used detect expression level antioxidant enzymes, flow cytometry intracellular reactive...
Mitophagy, known as the main mechanism of mitochondrial quality control, determines pathophysiology septic cardiomyopathy, although precise regulatory mechanisms remain elusive. Data from present study suggested that receptor-interacting protein kinase 3 (RIPK3) expression could be enhanced in response to lipopolysaccharide (LPS) challenge. Upregulated RIPK3 was accompanied by severe cardiac injury and dysfunction. Further examination revealed elevated subsequently inhibited Yes-associated...
To compare the different retinal blood flow velocities (BFVs) acquired with fields of view (FOVs) using function imager (RFI), twenty eyes healthy subjects were enrolled in study. Retinal microvessel BFV macula was both a wide FOV (35 degrees, 7.3 × mm 2 ) and commonly used small (20 4.3 ). The 35-degree trimmed to be equivalent 20-degree BFVs similar FOVs settings. With FOV, arteriolar venular significantly greater than (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Abstract Background To date, there have been very few studies that explored the relationship between headaches and computer use. The chief aim of this study is to investigate prevalence primary headache disorders among informational technology staff identify potential factors contributing it. Methods This a cross-sectional based on annual health checks employees from information industry. We identified 2216 members Beijing by stratified random sampling who met inclusion criteria. All...
The purpose of this study was to investigate the role amnioreduction in patients who underwent emergency cervical cerclage (ECC) with bulging membranes during second trimester. This retrospective comparative included 46 singleton pregnant women had dilation at least 1 cm beyond external os and ECC Third Affiliated Hospital Sun Yat-sen University between December 2016 2021. Cases were categorized as group ( n = 16) non-amnioreduction 30) according whether performed prior ECC. gestational age...
Abstract In this paper, hydroxylapatite (HA) nanoparticles were constructed through the ultrasound‐assisted dispersion method. Using scanning electron microscopy (SEM), we studied preparation methods of HA nanoparticles, and spherical with a size about 50 nm prepared. Besides, HA/PLA composite polylactic acid (PLA) as material. The effects different proportions on investigated before Fourier transform infrared spectroscopy (FTIR), X‐ray diffraction (XRD), Transmission microscope (TEM), SEM,...
It remains unclear whether gestational weight gain (GWG) during pregnancy is associated with Omicron infection in pregnant women. To investigate an increased risk of infection. This a retrospective case-control study women from The Third Affiliated Hospital Sun Yat-sen University December 1 to 31, 2022. Pregnant infected were compared those uninfected using chi-square statistics for categorical variables and t-tests or ANOVA continuous variables. Multivariable logistic regression, along...
Osteoarticular Tuberculosis (TB) is a challenging issue because of its chronicity and recurrence. Many drug delivery systems (DDSs) have been developed for general chemotherapy. Herein, we take advantage instant hydrogelation to in situ encapsulate drugs onto implants intraoperatively, optimizing the release profile against osteoarticular TB. First-line chemodrugs, i.e. rifampicin (RFP) isoniazid (INH) are firstly loaded on tricalcium phosphate (TCP). Then, encapsulating hydrogel fabricated...
Objective The research is engaged in developing an improved titanium skirt for keratoprosthesis, the aim of this study was to evaluate biocompatible keratoprosthesis novel design.Methods pure with three hands were first Sandblasted, and then bioactive hydroxyapatite coated on Sandblasted by a acid-alkali chemical treatment. A total 18 New Zealand white rabbits alkali burned rabbit corneas respectively divided into groups (Group A, B C;Group E, F G) simple random sampling methods.The modified...