A5001799788- Mesenchymal stem cell research
- Coronary Interventions and Diagnostics
- Electrospun Nanofibers in Biomedical Applications
- Radiopharmaceutical Chemistry and Applications
- Tissue Engineering and Regenerative Medicine
- Parasitic infections in humans and animals
- Gallbladder and Bile Duct Disorders
- Hydrogen's biological and therapeutic effects
- Cardiac Imaging and Diagnostics
- Toxoplasma gondii Research Studies
- Medical Imaging and Pathology Studies
- Systemic Sclerosis and Related Diseases
- Hernia repair and management
- Chronic Myeloid Leukemia Treatments
- Gas Dynamics and Kinetic Theory
- Cardiomyopathy and Myosin Studies
- Therapeutic Uses of Natural Elements
- Advanced MRI Techniques and Applications
- Diagnosis and Treatment of Venous Diseases
- Oral health in cancer treatment
- Cardiac electrophysiology and arrhythmias
- Hormonal Regulation and Hypertension
- Cardiac Valve Diseases and Treatments
- Minimally Invasive Surgical Techniques
- Spacecraft and Cryogenic Technologies
Siberian State Medical University
2004-2024
Ministry of Health of the Russian Federation
2020-2023
Institute for Molecular Medicine Finland
2014
Western University
2011
Helsinki University Hospital
2005-2006
University of Helsinki
2004-2006
RationaleEngraftment and survival of transplanted stem or stromal cells in the microenvironment host tissues may be improved by combining such with scaffolds to delay apoptosis enhance regenerative properties. AimsWe examined whether poly(lactic-co-glycolic acid) pharmacologically active microcarriers (PAMs) releasing vascular endothelial growth factor (VEGF) survival, differentiation, angiogenesis adipose tissue-mesenchymal (AT-MSCs).We analysed efficacy AT-MSCs conjugated PAMs a murine...
Abstract Longitudinal relaxation time in the rotating frame ( T 1 ρ ) was measured using continuous wave irradiation normal and infarcted mouse myocardium vivo. Significant increase found after 7 days of infarction when compared with reference or before infarction. Cine MRI histology were performed to verify severity The course infarct fits better granulation scar tissue formation than necrosis edema. results study show that could potentially be a noninvasive quantitative marker for...
<i>Background:</i> Accelerated arteriosclerosis remains a major limitation to therapeutic interventions such as angioplasty, stent deployment, and solid organ transplantation. Rapamycin, powerful new immunosuppressant set replace calcineurin inhibitors in the transplant setting, imatinib mesylate, receptor tyrosine kinase inhibitor, are both angioprotective. Here, we explored pharmacological interactions of these two agents rat model neointimal hyperplasia....
The effectiveness of ozone therapy in the treatment cancer pathology lies proven process destruction atypical cells due to inhibition vicious anaerobic metabolism. Ozone selectively causes death cells, since healthy have their own antioxidant defense system, while do not. for is an auxiliary method that involves effect oxygen-ozone layer on cancerous cellular structures. Numerous clinical studies confirm well tolerated and extremely rarely accompanied by side effects does not cause negative...
We describe here a mouse model of diffuse aortic remodelling triggered by combined endothelial denudation/vascular distension injury using novel balloon microcatheter. validated this in both outbred (NMRI) and inbred (BALB/c, C57BL/6) strains found evidence for differential strain susceptibility to neointimal hyperplasia, possibly attributable genetic factors. Neointimal lesions were approximately 50% smaller the strains, finding associated with profound cell loss media at early stages...
In Tomsk zonal hepatologic center 358 patients with obstructive parasitogenic jaundice have been operated (alveococcosis-based — 43, echinococcosis-based 17, opisthorchosis-based 298). Clinical presentations of hepatic failure before the surgery observed at 30,7% patients, more often under long and intensive cholestasis. Postsurgical has developed 23,1%. Intraportal medicine infusions play an important role in prophylaxis treatment along timely optimal surgery. Infusions permit to decrease...
Purpose of the study . To investigate efficacy focal destruction tissues local liver diseases, chole- and hemostasis created endoscopic cryoapplicator in operations on gallbladder. Material methods Review results surgical treatment 121 patients with various diseases (tumors, alveococcosis, parasitic non-parasitic cysts) gallbladder (chronic acute cholecystitis) using a new porous TiNi cryoapplicator. 49 were operated by an open method, 72 - laparoscopically. Hemo-and cholestatic control...
Rationale: Adipose tissue-derived mesenchymal stromal cells (AT-MSCs) may contribute repairing ischemic cardiovascular tissue. The engraftment and survival of transplanted in the harmful microenvironment host tissue be improved by combining stem with scaffolds to delay apoptosis enhance their regenerative properties. Objectives: We examined whether poly (lactide-co-glycolide) (PLGA) microspheres functionalized vascular endothelial growth factor (VEGF) survival, growth, differentiation...
Purpose of the study : to conduct a comparative analysis endoscopic retrograde transpapillary interventions in patients with chronic opisthorchiasis and obstructive jaundice various etiologies. Material Methods . The results treatment 129 etiologies who underwent correct bile duct, were analyzed. In order assess condition patients, general clinical methods set laboratory instrumental used. was carried out two groups, first drainage ducts out, second – either papillosphincterotomy...
КРАТКИЕ СООБЩЕНИЯ ■Трофические язвы -наиболее частое осложнение хронической венозной недостаточности нижних конечностей, которые встречаются примерно у 2% трудоспособного населения.Зачастую приводят к социальной дезадаптации пациентов, увеличивают сроки нетрудоспособности и снижают качество жизни больных.Представлено клиническое наблюдение эффективного комплексного консервативного лечения трофической пациентки с множественной лекарственной непереносимостью.Пациентке проведено стандартное обследование
Echinococcosis and alveococcosis are severe parasitic diseases. Only early surgical intervention is radical method of treatment. Rare clinical observation liver echinococcosis combined with described in the article. Literature data, comprehensive survey, treatment morphological analysis presented.
O191* Aims: Rapamycin is a powerful new immunosuppressant set to displace calcineurin inhibitors as primary maintenance therapy in the clinic. Evidence from experimental transplant models along with remarkable clinical success of rapamycin-coated stents preventing post-angioplasty restenosis, suggests that use rapamycin might reduce incidence arteriopathy (TA), major cause chronic graft rejection. However, acute rejection (a risk factor for TA) still occurs under treatment, do adverse...
The purpose of the study was to assess results Merzlikin-Paramonova's approach in liver surgeries. Material and Methods . topographical-anatomical spatial relationships were studied on 20 corpses, taking into account assessment criteria according A.Yu. Sozon-Yaroshevich. In clinical settings, applied treatment 81 patients with hepatic diseases (cancer, hemangioma, alveococcosis), who underwent radical palliative Short-and long-term outcomes during a 5 year follow-up analyzed. provided...
The possibility of using titanium nickelide (TiNi) cryoapplicator in the surgery nonparasitic cysts and liver hemangiomas was study. Material methods. analysis results surgical treatment patients with use TiNi carried out 26 31 various localization diameter. Results. It proved that a is as effective stationary cryoinstallation constant supply cryoagent (liquid nitrogen). Conclusion. increases effectiveness action on liver, causing their cryodestruction preventing recurrence these diseases,...