A5001894933- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac pacing and defibrillation studies
- Coronary Interventions and Diagnostics
- Congenital Heart Disease Studies
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Peptidase Inhibition and Analysis
- Frailty in Older Adults
- Surgical Simulation and Training
- Minimally Invasive Surgical Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac tumors and thrombi
- Aortic aneurysm repair treatments
- Esophageal and GI Pathology
- Tracheal and airway disorders
- Healthcare cost, quality, practices
- Tissue Engineering and Regenerative Medicine
- Telemedicine and Telehealth Implementation
Vita-Salute San Raffaele University
2020-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2020-2025
San Raffaele University of Rome
2021-2025
Cardiovascular Research Foundation
2024
Valve (United States)
2024
University of Padua
2020
Seoul National University Hospital
2020
Background Little is known about the impact of transcatheter mitral valve edge-to-edge repair on changes in left ventricular ejection fraction (LVEF) and effect an acute reduction LVEF prognosis. We aimed to assess after for both primary secondary regurgitation (PMR SMR, respectively), identify rates predictors reduction, estimate its Methods Results In this international multicenter registry, patients with PMR SMR undergoing were included. assessed (LVEFR), defined as relative decrease >15%...
Abstract Primary mitral regurgitation (PMR) is a valvular heart disorder that found treatment with surgery has been the gold standard for decades different techniques to approach this pathology. In last decade Transcatheter-Edge-to-Edge Repair (TEER) emerged as valid option type of pathology, in case surgical unsuitability. Others device well leaving less remark compared TEER. The article analyze old and new frontiers controversies phenotype.
Transcatheter tricuspid valve replacement (TTVR) is emerging as a promising surgical alternative for high-risk patients with regurgitation (TR). Nonetheless, the feasibility of more dedicated devices and need additional clinical evidence warrant further exploration. The purpose this study was to report 1-year outcomes TRAVEL (Transcatheter Right Atrial-Ventricular Valve Replacement With LuX-Valve) LuX-Valve system severe TR. A total 126 symptomatic TR were prospectively enrolled in...
Valve-in-ring procedures represent a feasible solution for high-risk patients with surgical repair failure. The risk of left ventricular outflow tract obstruction increases the challenge, and transcatheter approaches to prevent it are technically demanding often do not resolve it. We demonstrate feasibility safety transseptal balloon-assisted translocation anterior mitral leaflet valve-in-ring implantation.
The goal of this study was to assess the applicability a novel classification patients with tricuspid regurgitation based on 5 stages and evaluate outcomes following isolated surgical treatment.All treated valve repair or replacement (TVR) from March 1997 January 2020 at single institution were retrospectively reviewed. Patients divided according clinical-functional classification, degree together symptoms, right ventricular size function medical therapy. A total 195 treated; however, 23/195...
Abstract OBJECTIVES The EuroSCORE II is widely used to predict 30-day mortality in patients undergoing open and transcatheter cardiac surgery. aim of this study evaluate the discriminatory ability predicting a large cohort surgical mitral valve repair high-volume centre. METHODS A retrospective review our institutional database was carried on find all who underwent department from January 2012 December 2019. Discrimination assessed using receiver operating characteristic curves. maximum...
Heart failure is the worst outcome of all cardiovascular diseases and still represents nowadays leading cause mortality with no effective clinical treatments, apart from organ transplantation allogeneic or artificial substitutes. Although applied as gold standard, heart cannot be considered a permanent answer because several drawbacks, side effects administered immunosuppressive therapies. For increasing number patients, biological cardiac substitute based on decellularized autologous cells...
Introduction Unlike secondary mitral regurgitation (MR) in the setting of left ventricular disease, results surgical treatment severe atrial functional MR has remained largely unspoken. The aim this study is to analyze short midterm isolated ring annuloplasty patients with MR, comparison a matched cohort MR. Methods A retrospective review our Institutional database was carried out find all fulfilling strict echocardiographic criteria define control group disease selected. All underwent...
Abstract OBJECTIVES Aim of this study was to evaluate arrhythmic burden patients with Barlow’s disease and significant mitral regurgitation (MR) assess the impact repair on ventricular arrhythmias (VA) in group subjects. METHODS We prospectively included 88 consecutive referred our Institution from February 2021 May 2022. All enrolled underwent 24-h Holter monitoring before surgery. Sixty-three them completed 3 months echocardiographic follow-up. Significant defined as ≥1% premature beats/24...
Abstract OBJECTIVES Uncorrected severe mitral regurgitation (MR) due to posterior prolapse leads left ventricular dilatation. At this stage, valve repair becomes mandatory avoid permanent myocardial injury. However, which technique among neochoardae implantation and leaflet resection provides the best results in scenario remains unknown. METHODS We selected 332 patients with dilatation degenerative MR (PL) who underwent (85 patients) or PL (247 at our institution between 2008 2020. A...
Abstract Aim Transcatheter aortic valve implantation (TAVI) is a mainstay in the management of severe stenosis elderly patients, but there uncertainty on their long-term effectiveness. We aimed to assess outcome patients undergoing TAVI with Portico valve. Methods retrospectively collected data whom was attempted from 7 high-volume centres. Only theoretically eligible for 3 or more years follow-up were included. Clinical outcomes, including death, stroke, myocardial infarction,...
Mitral regurgitation (MR) due to commissural prolapse or flail represents a pattern of valve dysfunction that can be treated, among other techniques, by suturing the margins anterior and posterior leaflets in area (commissural closure). The very long-term results this technique have not been reported so far represent objective study.A retrospective review our institutional database was carried on querying for patients who underwent closure ring annuloplasty within time frame 1997-2007...
The aim of this study is to evaluate the immediate and mid-term effects omitting coronary artery bypass grafting in patients with moderate stenosis who have a primary indication for valvular surgery.We included 77 consecutive admitted our Institution aortic or mitral valve surgery between June 2012 2017 whom de novo diagnosis ≥50%, but <70% was made. In cohort, myocardial revascularization omitted. All these were free from angina ischaemia on echo ECG.There no in-hospital deaths. only 1...
Abstract OBJECTIVES After mitral repair for degenerative regurgitation (MR), no or mild (≤1+/4+) residual MR should remain. Occasionally patients are left with more than (&gt;1+/4+) a number of reasons. The aim this study was to assess the late implications such suboptimal in matched cohort study. METHODS From 2006 2013, total 2158 underwent our institution. Fifty (2.3%) &gt;1+ at hospital discharge (study group) were up 1:2 91 operated on during same period who discharged ≤1+...