A5100340940- Advanced Glycation End Products research
- Phytochemicals and Antioxidant Activities
- Bacterial Identification and Susceptibility Testing
- Neuroinflammation and Neurodegeneration Mechanisms
- Dye analysis and toxicity
- Cholesterol and Lipid Metabolism
- Laser-Matter Interactions and Applications
- Antimicrobial Resistance in Staphylococcus
- Infective Endocarditis Diagnosis and Management
- Metabolism and Genetic Disorders
- Enterobacteriaceae and Cronobacter Research
- Receptor Mechanisms and Signaling
- Estrogen and related hormone effects
- Anesthesia and Neurotoxicity Research
- Heme Oxygenase-1 and Carbon Monoxide
- Sexual Differentiation and Disorders
- High-pressure geophysics and materials
- Pharmacological Effects of Natural Compounds
- Acute Ischemic Stroke Management
- Alcohol Consumption and Health Effects
- Laser-Plasma Interactions and Diagnostics
- melanin and skin pigmentation
- Genomics and Phylogenetic Studies
- Circadian rhythm and melatonin
- Protein Hydrolysis and Bioactive Peptides
Tianjin University of Science and Technology
2021-2024
Central Hospital of Zibo
2023
Zhejiang University
2023
Air Force Medical University
2015-2021
Northwest A&F University
2017
Shanghai First People's Hospital
2015
Institute of Applied Physics and Computational Mathematics
2014
York General Hospital
2006
Dying tumor cells after irradiation could promote the proliferation of living might cause relapse and treatment failure. Our previous study showed that activated caspase-3 probably participates in repopulation. In this study, we investigated whether high mobility group box 1(HMGB1) is also involved Colorectal were irradiated. The cleaved (CC3) irradiated HMGB1 supernatant detected by Western blot. A large number colorectal (feeder cells) then co-cultured with a small luciferase-labeled...
The IDI-MRSA assay has a sensitivity of 96% and specificity when used to screen patients at extranasal sites. This verification study previously unverified swabs was undertaken in core medical laboratory using nonmicrobiology technologists trained sample processing, molecular work flow, PCR practice.
Scope d ‐chiro inositol (DCI), an isomer of inositol, possesses anti‐oxidative and endothelial protective properties. The mechanism by which DCI prevents dysfunction was investigated, with emphasis on oxidative stress. Methods results found to inhibit NOX4 induction enhance Nrf2 activity in palmitate (PA)‐stimulated cells, showing that suppressed Ser616 phosphorylation increased Ser637 Drp1 inhibited PA‐induced mitochondrial fission. Knockdown attenuated over‐expression the inhibitory effect...
Ligands of the translocator protein (18 kDa) (TSPO) have demonstrated rapid anxiolytic efficacy in stress responses and stress-related disorders. This is involved synthesis endogenous neurosteroids including pregnenolone, dehydroepiandrosterone, progesterone. These promote γ-aminobutyric acid-mediated neurotransmission central neural system (CNS). A TSPO ligand, N-benzyl-N-ethyl-2-(7,8-dihydro-7-benzyl-8-oxo-2-phenyl-9H-purin-9-yl) acetamide (ZBD-2) was recently synthesized. The purpose...
Hormone replacement therapy (HRT) is not recommended for treating learning and memory decline in menopausal women because it exerts adverse effects by activating classic estrogen receptors ERα ERβ. The membrane receptor G protein-coupled 30 (GPR30) has been reported to be involved modulation; however, the underlying mechanisms are poorly understood. Here, we found that GPR30 deletion astrocytes, but neurons, impaired female mice. Astrocytic depletion induced A1 phenotype transition,...
The radiation temperature TR and M-band fraction fM inside the vacuum Au hohlraum have been experimentally determined by a shock wave technique broadband soft x-ray spectrometer (SXS) on SGIII-prototype laser facility. From results of technique, is about 202 eV, 9% for hohlraums driven 1 ns flattop pulse 6 kJ energy. Continuous Phase Plate (CPP) beam smoothing applied in experiment, which increases to 207 eV while has almost no influence fM. Comparisons between from two kinds technologies...
Objectives To develop a rapid and low-cost method for 16S rDNA nanopore sequencing. Methods This was prospective study on sequencing method. We developed this barcoding by adding barcodes to the primer reduce reagent cost simplify experimental procedure. Twenty-one common pulmonary bacteria (7 reference strains, 14 clinical isolates) 94 samples of bronchoalveolar lavage fluid from children with severe pneumonia were tested. Results indicating low-abundance pathogenic verified polymerase...
This study assessed the role of Curcumin in acute pulmonary embolism (APE) and inflammation. Male rats were assigned into sham operation group, APE low-dose high-dose group for this study. Levels IL-1 β , TNF- α Interleukin-6 (IL-6) inflammatory indicators analyzed, including also, pathological changes lung tissue. We also High mobility box 1 (HMGB1), receptor advanced glycation end product (RAGE) Nuclear factor kappa B (NF- κ B) protein expressions. Results showed that, inflammation reduced...