A5101449845- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Mechanisms and Therapy
- MicroRNA in disease regulation
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Hepatitis B Virus Studies
- Immune cells in cancer
- interferon and immune responses
- Ultrasound and Hyperthermia Applications
- Liver physiology and pathology
- Cancer, Hypoxia, and Metabolism
- Pancreatitis Pathology and Treatment
- RNA Research and Splicing
- Liver Disease and Transplantation
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- RNA modifications and cancer
- Extracellular vesicles in disease
- Herpesvirus Infections and Treatments
- Ovarian cancer diagnosis and treatment
- Cancer-related gene regulation
Tumor Hospital of Xinjiang Medical University
2015-2024
Xinjiang Medical University
2015-2024
Affiliated Hospital of Qingdao University
2022
Qingdao University
2022
Lenvatinib is the first-line treatment for advanced hepatocellular carcinoma (HCC). We aimed to compare clinical outcomes of lenvatinib plus drug-eluting beads transarterial chemoembolization (DEB-TACE) versus alone in real-world practice.This retrospective analysis included 142 consecutive patients who received DEB-TACE and 69 as from 15 Chinese academic centers November 2018 2019. Overall survival (OS), progression-free (PFS), objective response rate (ORR) were evaluated by modified...
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and has an extremely poor prognosis. We aimed to determine latent relationships between TRIM36 regulation apoptosis Wnt/β-catenin pathway in HCC.Immunohistochemistry western blotting were used characterize aberrant expression HCC adjacent tissues. Clinical information was analyzed using Kaplan-Meier Cox methods. RNA-seq potential targets conducted detect TRIM36. Apoptosis assays cellular proliferation, invasion...
Programmed cell death (PCD) is thought to have multiple roles in tumors. Here, the of PCD-related genes were comprehensively analyzed evaluate their values hepatocellular carcinoma (HCC) diagnosis and prognosis. Gene expression single-cell data HCC patients, collected from public databases. The diagnostic prognostic differentially expressed explored by univariate multivariate Cox regression analyses. Single-cell further for immune cells feature genes. Finally, we evaluated quantitative...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Huang W, Yang S, You L, et al. Transcatheter arterial chemoembolisation (TACE) plus S-1 for the treatment of BCLC stage B hepatocellular carcinoma refractory to TACE. Contemporary Oncology/Współczesna Onkologia. 2016;20(6):468-474. doi:10.5114/wo.2016.65607. APA Huang, W., Yang, S., You, L., Liu, M., D., & Gu, P. (2016). Onkologia, 20(6), 468-474. https://doi.org/10.5114/wo.2016.65607 Chicago Wu-Kui, Shu-Fa...
Circular RNAs (circRNAs) have been uncovered to play an important regulatory function in the tumorigenesis of intrahepatic cholangiocarcinoma (ICC). Hsa_circ_0,019,054 was found be increased ICC. Here, we aimed explore action and mechanism hsa_circ_0,019,054 ICC carcinogenesis.Quantitative real-time PCR (qRT-PCR) western blotting were used detect levels genes proteins. The functional experiments performed using vitro 5-ethynyl-2'-deoxyuridine (EdU) assay, cell counting Kit-8 (CCK-8) flow...
Abstract Objective The aim of this study was to analyze whether Jinlong capsule could decrease adverse reactions after transcatheter arterial chemoembolization (TACE) in patients with hepatocellular carcinoma. Methods Eighty-two carcinoma were randomly divided into the control group and experimental group. On first day TACE, started receiving four capsules orally three times daily, whereas did not receive treatment. Results incidences erythropenia thrombocytopenia lower than those ( P =...
A Correction to this paper has been published: https://doi.org/10.1038/s41417-021-00338-0
Endometrial carcinoma (EC) is a type of epithelial malignancy prevalent in about 8% the total malignancies women. Development new treatment methods vital for improving prognosis endometrial cancer. High Intensity Focused Ultrasound (HIFU) safe method oncological with low complication rate. However, EC by HIFU rarely reported and its mechanism unclear. Herein, effects on progression were detected. Data confirmed inhibition tumor growth mice HIFU. Moreover, inhibited apoptosis. It...
Purpose: To investigate the biological function and mechanisms of circPDSS1 in triggering malignant progression renal cell carcinoma (RCC).
 Methods: Quantitative real-time polymerase chain reaction (qRT-PCR) was conducted to determine levels 50 pairs RCC para-cancerous tissues. The relationship between level pathological indices patients analyzed, while vitro effect regulating proliferation assessed using counting kit-8 (CCK-8), colony formation 5- ethynyl-2’- deoxyuridine (EdU) assay....
Abstract BackgroundObjective response rate (ORR) under mRECIST criteria after transarterial chemoembolization (TACE) has been identified as a surrogate endpoint of overall survival (OS). However, its optimal time-point remains controversial and may be influenced by tumor burden. We aim to investigate the surrogacy initial/best ORR in relation MethodsA total 1549 eligible treatment-naïve patients with unresectable hepatocellular carcinoma (HCC), Child-Pugh score ≤7, performance status ≤1...