- Musculoskeletal pain and rehabilitation
- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Sports injuries and prevention
- Respiratory Support and Mechanisms
- Muscle activation and electromyography studies
- Sepsis Diagnosis and Treatment
- Peripheral Artery Disease Management
- Myofascial pain diagnosis and treatment
- Balance, Gait, and Falls Prevention
- Pancreatic and Hepatic Oncology Research
- Anesthesia and Sedative Agents
- Cardiac Valve Diseases and Treatments
- Cardiovascular Issues in Pregnancy
- Cardiac Arrhythmias and Treatments
- Cardiovascular Health and Disease Prevention
- Nosocomial Infections in ICU
- Cardiovascular and Diving-Related Complications
- Diagnosis and Treatment of Venous Diseases
- Body Composition Measurement Techniques
- Pharmacological Effects and Toxicity Studies
- Lysosomal Storage Disorders Research
- Acute Kidney Injury Research
- Abdominal Surgery and Complications
- Drug Transport and Resistance Mechanisms
Tokyo Medical and Dental University
2023-2024
Health Sciences University of Hokkaido
2019-2024
Hokkaido University Hospital
2019-2023
Teikyo University Hospital, Mizonokuchi
2021
Teikyo University Hospital
2021
Teikyo University
2021
Saitama Prefecture
2019
Hokkaido University
1996-2018
NTT Medical Center
2008-2017
Asahi Kasei (Germany)
2016
Supplemental doses of antithrombin (AT) are widely used to treat sepsis-induced disseminated intravascular coagulation (DIC) in Japan. However, evidence on the benefits AT supplementation for DIC is insufficient. This multicenter retrospective observational study aimed clarify effect using propensity score analyses. Data from 3,195 consecutive adult patients admitted 42 intensive care units severe sepsis treatment were retrospectively analyzed; 1,784 diagnosed with (n = 715, group; n 1,069,...
Severe sepsis is a major concern in the intensive care unit (ICU), although there very little epidemiological information regarding severe Japan. This study evaluated 3195 patients with 42 ICUs throughout The had mean age of 70 ± 15 years and Acute Physiology Chronic Health Evaluation II score 23 9. estimated survival rates at 28 90 days after ICU admission were 73.6 56.3 %, respectively.
Journal Article Purification and Characterization of 3′-Phosphoadenosine-5′-Phosphosulfate: GalCer Sulfotransferase from Human Renal Cancer Cells Get access Koichi Honke, Honke 2 Biochemistry Laboratory, Institute, Hokkaido University School MedicineKita-ku, Sapporo 060 2To whom correspondence should be addressed at: Research Osaka Medical Center for Maternal Child Health, 840 Murodo-cho, Izumi, 590-02. Tel: +81-725-56-1220, Fax:+ 81-725-57-3021 Search other works by this author on: Oxford...
The administration of low-dose intravenous immunoglobulin G (IVIgG) (5 g/day for 3 days; approximate total 0.3 g/kg) is widely used as an adjunctive treatment patients with sepsis in Japan, but its efficacy the reduction mortality has not been evaluated. We investigated whether IVIgG associated clinically important outcomes including intensive care unit (ICU) and in-hospital mortality.This a post-hoc subgroup analysis data from retrospective cohort study, Japan Septic Disseminated...
Shoulder movements that involve unilateral and bilateral flexion, extension, abduction, asymmetrical flexion-extension cause the activity of trunk muscles. There has not been a fixed consensus on onset deep muscle activities including psoas major (PM), quadratus lumborum (QL), transversus abdominis (TrA), lumbar multifidus (MF) during shoulder movements. The purpose this study was to measure electromyographic muscles rapid clarify coordinated pattern 11 movements.Thirteen men participated in...
Objective: The aim of this study was to elucidate the activities hip flexor muscles during straight leg raising (SLR) in healthy subjects. We also investigated these SLR with deep flexion, abduction, and external rotation. Methods: ten dominant right legs male volunteers were analyzed study. Twelve motion tasks performed; comprised combinations flexion at 30°, 45°, 60°; abduction 0° 20°; rotation 30°. psoas major (PM) iliacus (IL) measured using fine-wire electrodes, whereas rectus femoris,...
Objective The purpose of this study is to investigate the physical changes lower leg muscles in compartment by observing shear wave velocity gastrocnemius, soleus and tibialis anterior with time sitting position for 2 hours after elevation leg. Materials methods subjects were 24 healthy adult males (average age 26.6 years). Shear was measured Aplio 500 immobilized immediately start sitting, 60 minutes 120 sitting. After raised 3 minutes, then again. Results In lateral medial there a...
Background Neck and shoulder exercises are recommended to improve Shoulder Pain (NSP). However, it is unclear why for the neck NSP, methods evaluating effects of these have not been clear. Objective The purpose this study was investigate time-dependent changes in stiffness extensor muscles due prolonged sitting effect exercise. Methods Twenty-five healthy adult women sat with their hands on a desk 90 min looking at computer screen then performed Shear wave velocities (SWV) (the upper...
Purpose: To investigate morphological changes in the infrapatellar fat pad (IPFP) during active knee extension using ultrasonography. Methods: IPFP deformity from 30 ∘ flexion to full was recorded thickness and patellar tendon-tibial angle were evaluated on 26 healthy knees first session nine second session. Intra-rater inter-rate reliability coefficient of variation (CV) intraclass correlation (ICC) types (1, 3) (2, 3), respectively. Absolute assessed standard error measurement (SEM)....
Introduction: Prolonged sitting causes leg discomfort. We evaluated shear wave velocity (SWV) of muscles, circumference, and discomfort associated with 2 h sitting. Methods: Twenty-one middle-aged men 19 women participated in the study. SWV circumference was measured just after sitting, 60 min, 120 3 min raising. Leg assessed before min. Results: significantly greater than increased over time, decreased The percentage increase lower men, it time. both women. Discussions: Because is...
BACKGROUND: The activity of deep trunk muscles (psoas major; PM, quadratus lumborum; QL, transverse abdominis; TrA, and lumbar multifidus; MF) in response to external perturbation is not clearly known. OBJECTIVE: This study aimed record the onset amount during sagittal plane perturbations. METHODS: Fourteen healthy males participated this study. right was recorded using wire electrodes. In standing, participants performed three tasks: a pendulum impacted from anterior with predictable...