A5007289228- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Cardiac pacing and defibrillation studies
- Neurological disorders and treatments
- Fungal Infections and Studies
- Cardiovascular Effects of Exercise
- Cardiac Valve Diseases and Treatments
- Phonocardiography and Auscultation Techniques
- Autopsy Techniques and Outcomes
- Nanoparticle-Based Drug Delivery
- Agricultural and Food Sciences
- ECG Monitoring and Analysis
- Neurology and Historical Studies
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Vector-Borne Animal Diseases
- Pain Management and Treatment
- Single-cell and spatial transcriptomics
- Vector-borne infectious diseases
- Insect symbiosis and bacterial influences
- Actinomycetales infections and treatment
- Toxoplasma gondii Research Studies
- Cardiovascular Conditions and Treatments
Universidade de Brasília
2003-2024
Centro Hospitalar de Vila Nova de Gaia
2024
Petrobras (Brazil)
2007
Universidade Federal da Bahia
2003
Fundação Oswaldo Cruz
2002-2003
Brazilian Society of Tropical Medicine
1993
Universidade Federal do Paraná
1993
When those carrying out pacing of the His bundle found procedure was able to correct pattern left branch block, they presumed that block consequence discrete lesions in bundle. They further distal a lesion produced normalization QRS complex.1,2 This novel concept dependent on assumption located longitudinally dissociated bundle, ignoring evidence functional lateral connections within which could theoretically circumvent an area conduction block.
We describe a simple method using percoll gradient for isolation of highly enriched human monocytes. High numbers fully functional cells are obtained from whole blood or buffy coat cells. The use laboratory equipment and relatively cheap reagent makes the described convenient approach to obtaining
It is almost 100 years ago since Mahaim described the so-called paraspecific connections between ventricular conduction axis and crest of muscular septum, believing such pathways to be ubiquitous. These pathways, however, have yet considered as potential for septal activation during His bundle pacing.So explore hypothesis that specialised might provide substrate pacing, we compared findings from 22 serially sectioned histological datasets 34 different individuals undergoing pacing.We found...
Conduction problems still occur following transcatheter aortic valvar replacement. With this in mind, we have assessed the relationship of conduction axis to root. We used serial histological sections, made perpendicular base triangle Koch nine hearts, and root 11 hearts. first defined extent fibrous tissues forming boundaries an infero-septal recess subaortic outflow tract, found all datasets but one. When was present, penetrated through its rightward wall, giving rise left bundle branch...
The arrangement of the conduction axis is markedly different in various mammalian species. Knowledge such variation may serve to question validity using animals as prospective models for design systems clinical use.We compared atrioventricular human, murine, canine, porcine, and bovine hearts, examining serially sectioned datasets from 20 16 3 5 1 hearts. We also analysed computed tomographic obtained bovines one human heart. Unlike situation heart, there no formation an fibrous membranous...
Este trabalho apresenta uma avaliação do efeito terapêutico extrato hidroalcólico da casca de Anacardium occidentale L sobre a Leishmania (Viannia) brasiliensis. No modelo in vitro o vegetal mostrou-se ativo contra promastigotas parasita, contrastando com vivo, onde não se observou qualquer atividade curativa.
Using transparent specimens with a dual color injection, microscopy, and computer tomography, this report shows that the right left ventricular subendocardial Purkinje networks are connected by an extensive septal network in bovine heart. The is present along entire septum except at free zone below valves. Being only communication of basal wall, supraventricular crest enigmatic but not, any means, hidden muscular structure. It one last structures to be activated human shown here connects...
Magnetic nanoparticles (MNPs) have been successfully tested for several purposes in medical applications. However, knowledge concerning the effects of nanostructures on elderly organisms is remarkably scarce.To fill part this gap, work aimed to investigate biocompatibility and bio-distribution aspects magnetic coated with citrate (NpCit) both young healthy mice.NpCit (2.4 mg iron) was administered intraperitoneally, its toxicity evaluated 28 days through clinical, biochemical, hematological,...
It was Sunao Tawara who, in 1906, established the foundations for knowledge of arrangement atrioventricular conduction axis man and other mammals. Study hearts ungulates a central part his investigation, which assessed species, including man. He described several subtle differences between We have now ourselves studied cardiac tissue ox heart, comparing our findings with man, providing new insights into illustrated by Tawara. is, perhaps, surprising that these differences, although subtle,...
Abstract In the human heart, atrioventricular node is located toward apex of triangle Koch, which also at inferior pyramidal space. It adjacent to portion membranous septum, through it penetrates become bundle. Subsequent its penetration, conduction axis on crest ventricular sandwiched between muscular septum and component where gives rise ramifications left bundle branch. contrast, bovine has a long non‐branching component, into thick having skirted main cardiac bone rightward half...
The TH1/TH2 paradigm has been largely used in the interpretation of several diseases, particularly leishmaniasis. As far as we know there is no mathematical description this model related to We have extended and modified a previous published set equations 1 order adapt it leishmanial disease particularities. main modifications were: (1) analysis logistic exponential parasite growth curves, (2) assumption TH2 arm immune response having positive action on growth. three simultaneous...
Dextran-functionalized maghemite fluid (DexMF) has been tested to treat Ehrlich-solid-tumor-bearing mice, evidencing its potential use in mediating magnetohyperthermia breast cancer treatment. However, although magnetic nanoparticles tend accumulate tumor tissues, part of the nanomaterial can reach blood stream, and then organism. The aim this study was investigate acute systemic effects intratumoral injection DexMF treatment an advanced clinical Ehrlich-solid-tumor, assessed through...
Axenic culture in modified Grace's medium was used to induce metacyclogenesis of Leishmania (Viannia) braziliensis vitro. Morphological characteristics, lectin agglutination profiles, susceptibility complement lysis, and infectivity vivo were compared between metacyclic promastigotes mid-log phase growth. Short, arrow-like round, oval defined as putative forms on the basis being highly motile free swimming, with a small cell body long flagellum. These increased during > 80% whereas...
Longitudinal dissociation of the aggregated specialized cardiomyocytes within non-branching portion atrioventricular conduction axis has proved a controversial topic for both morphologists and electrophysiologists. We have now used morphological methods, including three-dimensional assessment, to revisit, in human, canine, bovine hearts, presence or absence interconnections between making up bundle. analyzed three datasets from human canine two using longitudinal orthogonal serial...