A5060512047- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Rheumatoid Arthritis Research and Therapies
- Nutritional Studies and Diet
- Workplace Health and Well-being
- Pregnancy and Medication Impact
- Consumer Attitudes and Food Labeling
- Sodium Intake and Health
- Maternal and fetal healthcare
- Child Nutrition and Feeding Issues
- Health and Lifestyle Studies
- Child Nutrition and Water Access
- Pancreatic function and diabetes
- Behavioral Health and Interventions
- Infant Development and Preterm Care
- Hemoglobin structure and function
- Childhood Cancer Survivors' Quality of Life
- Heme Oxygenase-1 and Carbon Monoxide
- HIV/AIDS Research and Interventions
- Cleft Lip and Palate Research
- HIV/AIDS oral health manifestations
- Genetic factors in colorectal cancer
- Autoimmune and Inflammatory Disorders Research
King's College London
2010-2025
Queen's University Belfast
2017-2025
Medical University of South Carolina
2017-2024
The Ohio State University
2023-2024
Kings Health Partners
2023
The Ohio State University Wexner Medical Center
2023
Shaker Heights Public Library
2021
Nassau University Medical Center
2019
University College Cork
2003-2016
King's College Hospital NHS Foundation Trust
2012
The objective of this paper is to provide a detailed evaluation type 2 diabetes mellitus research output from 1951-2012, using large-scale data analysis, bibliometric indicators and density-equalizing mapping. Data were retrieved the Science Citation Index Expanded database, one seven curated databases within Web Science. Using Boolean operators "OR", "AND" "NOT", search strategy was developed estimate total number published items. Only studies with an English abstract eligible. Type 1...
To examine if employees with higher nutrition knowledge have better diet quality and lower prevalence of hypertension. Cross-sectional baseline data were obtained from the complex workplace dietary intervention trial, Food Choice at Work Study. Participants included 828 randomly selected (18–64 years) recruited four multinational manufacturing workplaces in Ireland, 2013. A validated questionnaire assessed knowledge. Frequency Questionnaires (FFQ) measured which a DASH (Dietary Approaches to...
Objective A process evaluation of the Children and Young People’s Health Partnership (CYPHP) model integrated care for interpretation trial findings building evidence on implementation children. Design mixed-methods evaluation. Setting CYPHP was implemented at scale across two inner-city London boroughs in South London, England, as a pragmatic cluster-randomised controlled involving nearly 98 000 children, with nested Participants Linked data were available from 73 participants. Qualitative...
Dietary behaviour interventions have the potential to reduce diet-related disease. Ample opportunity exists implement these in workplace. The overall aim is assess effectiveness and cost-effectiveness of complex dietary focused on environmental modification alone or combination with nutrition education large manufacturing workplace settings. A clustered controlled trial involving four multinational workplaces Cork will be conducted. intervention design has been developed using Medical...
Ambiguity exists regarding the effectiveness of workplace dietary interventions. Rigorous process evaluation is vital to understand this uncertainty. This study was conducted as part Food Choice at Work trial which assessed comparative a environmental modification intervention and an educational both alone in combination versus control workplace. Effectiveness terms employees’ intakes, nutrition knowledge health status four large manufacturing workplaces. The aimed examine barriers...
Abstract Background HIV remains a major public health issue, especially in Eastern and Southern Africa. Pre-exposure prophylaxis is highly effective when adhered to, but its effectiveness limited by cost, user acceptability uptake. The cost of non-inferiority phase III trial likely to be prohibitive, thus, it essential select the best possible drug, dose schedule advance. aim this study, Combined Adolescent PrEP Prevention Study (CHAPS), investigate pre-exposure (PrEP) required for...
OBJECTIVE This study was conducted to determine the utility of tubular (urinary/plasma neutrophil gelatinase-associated lipocalin [NGAL] and urinary kidney injury molecule 1 [KIM-1]) glomerular (estimated filtration rate [eGFR]) biomarkers in predicting preeclampsia (PE) pregnant women with type diabetes mellitus (T1DM) who were free microalbuminuria hypertension at first trimester. RESEARCH DESIGN AND METHODS a prospective T1DM pregnancy. Maternal plasma NGAL, KIM-1 (ELISA frozen samples),...
In diabetes haptoglobin (Hp) 2 vs Hp 1 allelic product is associated with cardiac and renal complications. Few studies report both phenotype levels. a Fenofibrate Intervention Event Lowering in Diabetes (FIELD) trial substudy we evaluated the phenotype, levels, fenofibrate effects.
The risk for preeclampsia (PE) is enhanced ~4-fold by the presence of maternal type 1 diabetes (T1DM). Vitamin D essential healthy pregnancy. We assessed total, bioavailable, and free concentrations plasma 25-hydroxyvitamin (25(OH)D), 1,25-dihydroxyvitamin (1,25(OH)2D), vitamin binding protein (VDBP) at ~12, ~22, ~32 weeks’ gestation (“Visits” (V) 1, 2, 3, respectively) in 23 T1DM women who developed PE, 24 remained normotensive, 19 non-diabetic, normotensive (reference controls). 25(OH)D...
Abstract Purpose The Child Health Utility-9 Dimensions (CHU9D) is a patient-reported outcome measure to generate Quality-Adjusted Life Years (QALYs), recommended for economic evaluations of interventions inform funding decisions. When the CHU9D not available, mapping algorithms offer an opportunity convert other paediatric instruments, such as Paediatric Quality Inventory™ (PedsQL), onto scores. This study aims validate current PedsQL mappings in sample children and young people wide age...
The incidence of preeclampsia (PE) is increased in women with diabetes (∼20% vs ∼5% the general population), and first trimester lipoprotein profiles are predictive. Haptoglobin (Hp), a protein functional genetic polymorphisms, has antioxidant, anti-inflammatory, angiogenic effects. Among people diabetes, Hp 2-2 phenotype associated cardiorenal disease.To investigate whether PE type 1 mellitus (T1DM) and/or modulates lipoprotein-associated risks.Multicenter prospective study T1DM...
Pediatric settings often use a patient-centered medical home model in caring for patients the outpatient setting and attempting to connect inpatient care with follow-up. This has proven be beneficial many aspects of patient care, but there needs good transition between services. Our goal this study is determine association particular variables adherence follow-up after general stay, pediatric population.In retrospective sample 221 patients, we such as demographics, history, hospital...
Abstract Disclosure: C. Kelly: None. B.M. O'Donnell: A 33 year old female presented to the Endocrinology clinic for evaluation of a 1.4 cm thyroid nodule. She has relevant past medical history Familial Adenomatous Polyposis (FAP). was diagnosed with FAP in her early 20s after she had developed hematochezia. When underwent first endoscopy reports there “were hundreds polyps” as well multiple stomach ulcers/polyps. In 2012 total proctocolectomy ileal pouch-anal anastomosis (IPAA). Then August...
<h3>Background</h3> Current measurements of dietary and urinary sodium are fraught with methodological difficulties. Dietary methods tend to underestimate consumption due under-reporting discretionary sources salt (added at the table, or during cooking). The 24-hour urine collection method which is considered 'gold standard' burdensome potentially limited by under-collection. Several have been used predict excretion from spot samples, including arithmetic extrapolation application predictive...
Objective: Preeclampsia (PE) occurs about four times more frequently in women with than without diabetes. Vitamin D is essential for healthy pregnancy. We investigated detailed measures of maternal plasma 25-hydroxyvitamin (25(OH)D), 1,25-dihydroxyvitamin (1,25(OH)2D), and vitamin binding protein (VDBP) to define associations PE Type 1 diabetes (T1DM). Design setting: A multicentre prospective study at ~12, ~22 ~32 weeks’ gestation (‘Visits’ (V) 1, 2, 3, respectively). Population: studied 23...
Objective To understand the reach of community health worker (CHW) programme in remote and non-remote districts Afghanistan. Methods Using data collected from Ministry Public Health’s National Health Management Information System, we conducted a population-based study 2018 to 2019 401 across 34 provinces We assessed availability CHWs, antenatal visits (ANV) postnatal (PNV) by CHW supplies. Districts were classified as if district centre was >2 hours any form transport provincial capital,...
Background: Patients with RA have an increased prevalence of cardiovascular disease (CVD). This is due to traditional risk factors and the effect chronic inflammation. TNF antagonists are potent suppressors inflammation may reduce CVD. We performed a systematic literature review determine whether affect clinical CVD events in RA. Methods: searched Medline, Embase, Cochrane database, DARE, HTA Science Citation Index from 1980-2008. Papers were included if they assessed relationship between...