Coriann E. Dorgay
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Immunodeficiency and Autoimmune Disorders
- HIV, Drug Use, Sexual Risk
- Viral gastroenteritis research and epidemiology
- Machine Learning in Healthcare
- Metabolomics and Mass Spectrometry Studies
- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
Yale University
2021-2022
As Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to spread, characterization of its antibody epitopes, emerging strains, related coronaviruses, and even the human proteome in naturally infected patients can guide development effective vaccines therapies. Since traditional epitope identification tools are dependent upon pre-defined peptide sequences, they not readily adaptable diverse viral proteomes. The Serum Epitope Repertoire Analysis (SERA) platform leverages a...
Abstract Over the last century, outbreaks and pandemics have occurred with disturbing regularity, necessitating advance preparation large-scale, coordinated response. Here, we developed a machine learning predictive model of disease severity length hospitalization for COVID-19, which can be utilized as platform future unknown viral outbreaks. We combined untargeted metabolomics on plasma data obtained from COVID-19 patients (n = 111) during healthy controls 342), clinical comorbidity 508) to...