A5108825992- Effects and risks of endocrine disrupting chemicals
- Extracellular vesicles in disease
- Air Quality and Health Impacts
- Toxic Organic Pollutants Impact
- Psychological Treatments and Assessments
- Radiation Therapy and Dosimetry
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Fatty Acid Research and Health
- Advanced Glycation End Products research
- Metabolomics and Mass Spectrometry Studies
- Healthcare professionals’ stress and burnout
- Pain Management and Placebo Effect
- Nutritional Studies and Diet
- Respiratory Support and Mechanisms
- Cardiac Fibrosis and Remodeling
- Advanced Nanomaterials in Catalysis
- Herbal Medicine Research Studies
- Ferroptosis and cancer prognosis
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Essential Oils and Antimicrobial Activity
- Thyroid Cancer Diagnosis and Treatment
Shanghai Jiao Tong University
2023-2025
Shanghai Sixth People's Hospital
2023-2025
Suzhou Municipal Hospital
2025
Nanjing Medical University
2025
Huawei Technologies (China)
2025
Anhui Medical University
2024
University of Science and Technology of China
2024
Shanghai Sunshine Rehabilitation Center
2023
Guangxi University of Chinese Medicine
2023
Tongji University
2023
Importance Polybrominated diphenyl ethers (PBDEs) are an important group of persistent organic pollutants with endocrine-disrupting properties. However, prospective cohort studies regarding the association PBDE exposure long-term health outcomes, particularly mortality, lacking. Objective To examine environmental to PBDEs risk all-cause and cause-specific mortality. Design, Setting, Participants This nationally representative study used data from National Health Nutrition Examination Survey...
Curative-intent radiotherapy for multiple lung metastases with more than 10 lesions is limited by dose constraints and respiratory motion. Carbon ion (CIRT) leverages the Bragg peak precision hypofractionation, while high-frequency oscillatory ventilation (HFOV) minimizes motion under anesthesia. This study evaluates feasibility of combining CIRT HFOV in treating ≥15 metastases. Two patients received single-fraction (50 Gy(RBE)) targeting all lesions. Case 1 (16 bilateral lung,...
Cardiac remodeling in response to disease or tissue damage severely impairs heart function. Therefore, the description of molecular mechanisms responsible is essential for development effective therapies. Trbp (Tarbp2) a multifunctional RNA-binding protein that during development, but its role adult and cardiac remains unknown. We generated inducible conditional knockout mice delete from cardiomyocytes young adults (Trbp-cKOs). While Trbp-cKO did not display detectable phenotype, under...
<p>In recent decades, the incidence of neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s (PD) has risen continuously, significantly impairing patients’ quality life while imposing growing economic social burdens. Traditional treatments exhibit limited effectiveness in halting progression. Non-invasive neuromodulation techniques, utilizing electromagnetic fields, light, or ultrasound, have emerged promising strategies to modulate neural activity alleviate...
Alzheimer's disease (AD) is the most common neurodegenerative in elderly without a cure.1 Although amyloid cascade hypothesis mainstream theory of AD pathogenesis for decades, it has been challenged due to unsatisfied outcomes clinical trials that aim mitigate plaque burden. Emerging evidence suggested excessive generation reactive oxygen species (ROS) including superoxide anion, hydroxyl radical, and H2O2 key process induce neuroinflammation neuronal loss AD, implicating ROS as promising...
Objective: The evidence regarding the associations of circulating metabolic biomarkers with hypertension risk is scarce. We aimed to examine between metabolites and hypertension. Methods: included 49 422 individuals free at baseline a mean (SD) age 53.5 (8.0) years from UK Biobank. Nuclear magnetic resonance spectroscopy was used quantify 143 individual metabolites. Multivariable-adjusted Cox regression models were estimate hazard ratios 95% confidence intervals (CIs). Results: During...
<title>Abstract</title> Introduction; The aim of this study was to investigate the safety and feasibility high-frequency oscillatory ventilation (HFOV) technique for management respiratory motion in patients with thoracoabdominal malignancies undergoing heavy ion precision therapy. Methods; A retrospective analysis clinical data from 30 malignant tumors treated therapy under control at one Cancer Hospital conducted January 2023 March 2024. Patient's general conditions, motion, other...
Abstract Objectives The aim of this study was to investigate the safety and feasibility high-frequency oscillatory ventilation (HFOV) technique for management thoracoabdominal malignancies in patients undergoing heavy ion therapy. Methods A retrospective analysis clinical data from 20 with malignant tumors treated therapy under control at Gansu Province Wuwei Cancer Hospital conducted January 2023 July 2023. Patient's general conditions, respiratory motion, other indicators were analyzed...
Staphylococcus aureus is a prevalent cause of lung infections in hospitals and communities, can wide spectrum human infections. Due to the bottleneck caused by antibiotic resistance substantial increases morbidity mortality, targeting virulence factors released S. as an alternative prevention treatment method has become promising approach. Ampelopsin, component vine tea, potential for treating aureus-induced acute injury. In this study, effects ampelopsin were investigated on mouse model...
Background: Melanoma is a highly malignant tumor. Currently, immune-checkpoint blockade (ICB) therapy has good effect on melanoma; however, the efficiency of this still low. Thus, combination new therapeutic targets and ICB may be essential in treatment melanoma.Methods: In study, RNA-seq single-cell data melanoma were retrieved from Gene Expression Omnibus (GEO) database. The protein expression quantitative trait loci (eQTL) found eQTLGen Genotype-Tissue (GTEx) databases, SMR analysis was...