A5100439447- Vestibular and auditory disorders
- Phagocytosis and Immune Regulation
- Peripheral Neuropathies and Disorders
- Pain Mechanisms and Treatments
- Complement system in diseases
- Pancreatic and Hepatic Oncology Research
- Herpesvirus Infections and Treatments
- Genetic Neurodegenerative Diseases
- Ophthalmology and Eye Disorders
- Shoulder Injury and Treatment
- Musculoskeletal pain and rehabilitation
- Mobile Health and mHealth Applications
- Optical Imaging and Spectroscopy Techniques
- Facial Nerve Paralysis Treatment and Research
- Heme Oxygenase-1 and Carbon Monoxide
- Inflammatory Myopathies and Dermatomyositis
- Ferroptosis and cancer prognosis
- Transcranial Magnetic Stimulation Studies
- Digital Imaging in Medicine
- Plant Physiology and Cultivation Studies
- Radiopharmaceutical Chemistry and Applications
- Social and Behavioral Studies
- Hepatitis B Virus Studies
- Scarabaeidae Beetle Taxonomy and Biogeography
- Hereditary Neurological Disorders
Third People's Hospital of Hangzhou
2023-2025
Ningbo Kangning Hospital
2025
Ningbo University
2025
Annexon Biosciences (United States)
2022-2025
Shanghai Jiao Tong University
2023-2024
Shandong Eye Hospital
2024
Shandong First Medical University
2024
Chengdu Second People's Hospital
2024
Shanghai Sixth People's Hospital
2024
AOL (United States)
2024
Cardiovascular morbidity and mortality are higher among patients with type 2 diabetes, particularly those concomitant cardiovascular diseases, than in most other populations. We assessed the effects of lixisenatide, a glucagon-like peptide 1–receptor agonist, on outcomes diabetes who had recent acute coronary event.
Studies have shown the clinical effects of repetitive transcranial magnetic stimulation (rTMS) on depression in Alzheimer's disease (AD). However, underlying mechanisms remain poorly understood. The measurement brain activation links neurobiological and functional aspects but is challenging patients with dementia. This study investigated influence rTMS cortical AD depressive symptoms, measured using near-infrared spectroscopy (fNIRS) during a verbal fluency task. In this randomized,...
Introduction Chronic pain is closely related to frailty. Methods A total of 300 older adult patients diagnosed with HZ were selected and admitted our hospital in 2024. basic data questionnaire gathered baseline information, the FRAIL scale was employed evaluate their initial frailty status. Patients who non-frail at followed up for 3 months. They categorized into PHN group non-PHN based on occurrence neuropathic during follow-up. Diverse scales frailty, nutritional status, anxiety,...
Guillain-Barré syndrome (GBS) is an acute autoimmune peripheral neuropathy driven by autoantibodies and classical complement pathway activation. Despite treatments with intravenous immunoglobulin or plasma exchange, GBS remains characterized variability in recovery high incidence of residual disabilities. This randomized, double-blind, placebo-controlled Phase 1 trial evaluated the safety, tolerability, pharmacokinetics ANX005, a novel therapeutic targeting cascade. Patients recent-onset...
Abstract Background and objectives Frozen shoulder is a common painful disease of the joint characterized by structural changes in joint, restricting both active passive activities. Proprioceptive neuromuscular facilitation (PNF) effectively improved maintained range motion; however, it not clear whether can improve structure patients with frozen shoulder. This pilot study used magnetic resonance imaging (MRI) observation to assess improvement local upon PNF treatment elucidate target based...
This study addresses the low water productivity (WP) of traditional flood irrigation (FI) and mismatch between wet zone surface drip (SDI) root activity layer fragrant pear. A fixed field experiment was conducted in Xinjiang, northwest China 2021 − 2023. The designed as a two-factor, completely randomized trial with three lateral depths Subsurface (SSDI) gradients set at 20 cm (D1), 30 (D2) 40 (D3) gradients: W1 (3750 m³ ha−1); W2 (5250 W3 (6750 ha−1), using SDI ha−1) FI (9750 controls....
Tuesday, April 25April 25, 2023Free AccessA Phase 2 Open-Label Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous ANX005 in Patients with, or at Risk of, Manifest Huntington’s Disease (HD) (S32.009)Rajeev Kumar, Daniel Claassen, Ann Mongan, Benjamin Hoehn, Ping Lin, Ellen Cahir-Mcfarland, Chenying Guo, Vladislav Volman, Lori Taylor, Priya Chandra, Ted Yednock, Henk-Andre KroonAuthors Info & AffiliationsApril 2023 issue100...
The Epley maneuver is useful for the otoconia to return from long arm of posterior semicircular canal into utricle. To move out short and utricle, we need different maneuvers.To diagnose short-arm type BPPV treat them with bow-and-yaw maneuver.171 cases were diagnosed as based on a positive Dix-Hallpike maneuver. We first attempted patients then performed again. If repeated gave negative results, patient considered have been cured by maneuver; otherwise, probably long-arm existed treated...
Intercellular adhesion molecule 1 (ICAM-1) plays prominent roles in mediating cell-cell which also facilitates B cell activation and differentiation with the help from CD4
Located deep in the temporal bone, semicircular canal is a subtle structure that requires spatial coordinate system for measurement and observation. In this study, 55 eyeball models were obtained by segmentation of MRI data. The was established taking top common crus bottom as horizontal plane. First, plane equation according to centerline canals. Then, parameters equation, normal vectors obtained. Finally, average unit vector each calculating value vectors. standard left posterior canal,...
Internet gaming disorder (IGD) can seriously impair an individual's physical and mental health. However, unlike the majority of those suffering from substance addiction, individuals with IGD may recover without any professional intervention. Understanding brain mechanisms natural recovery provide new insight into how to prevent addiction implement more targeted interventions.Sixty were scanned by using a resting-state fMRI assess region changes associated IGD. After 1 year, 19 no longer met...
Abstract The management of surgical instruments is related to the safety and efficiency operations, a information system (SIIMS) has been developed. aim current study explore application value SIIMS in sports medicine specialty. A set self-developed for surgeries was applied study. verified by comparing instrument manipulation before after its application, with accidents, repair rate, scrap rate use as indicators. Through SIIMS, incidence accidents decreased from 3.7 times 1.8 (P = 0.02),...
<h3>Background</h3> ANX005 is a humanized monoclonal antibody designed to inhibit C1q. <h3>Aims</h3> Report final results of ANX005-HD-01: Phase 2 study patients with or at risk manifest HD. <h3>Methods/Techniques</h3> Eligible (CAP>400) received intravenous every weeks (wk) through wk22 (NCT04514367). Endpoints were assessed on-treatment wk24, off-treatment follow-up wk36 (n=23). Primary objectives included safety/tolerability, pharmacokinetics (PK), and C1q, C4a, NfL levels (CSF...
Abstract Background Toe dorsiflexion is considered to be an important cause of plantar fasciitis, and the deep peroneal nerve (DPN) only innervating ankle joint toe dorsiflexion. We hypothesized that blocking DPN at lower part tibia can reduce toes rest in motion, thereby reducing fascia tension, will not affect patient's normal activities. Methods Under ultrasound guidance, a block was performed 2 cm above joint. Blocking twice week for two consecutive weeks. The VAS pain scores movement...
Focusing on the influencing factors of operation and processing process reusable medical devices, management problems devices are analyzed from processes device assembly, packaging, handover, inventory information recording. In specific practice designing intelligent control system in different periods addition, disinfection, transfer, transportation, distribution, recycling to scrapping integrated into service system. Through changes treatment, this study comprehensively explores innovative...
Objective:To study the characteristics and clinical value of spontaneous nystagmus in patients with peripheral vestibular dysfunction.Method:Sixty cases acute unilateral dysfunction were studied.All diagnozed as neuritis(VN) . The relationship between SN disease duration,DP UW analyzed.Result:SN was present in49 patients(81.7%)and absent remaining 11(18.3%).The intensity ranged from 0.5°/s-20.4°/s had negative correlation duration(r=-0.478，P<0.01). divided into 3 groups (mild,medium severe)...
This research aims to assess the essential variables that delineate implementation of radiotherapy in clinical pathway breast cancer patients from Stages 0 II. The evaluation focuses on a sample 8602 collected by SEER program 2007 2012 Atlanta. We developed logistic regression model measure level concordance for occurrence after lumpectomy surgery. calculated accuracy estimate model's measure. Our study determined multiple factors, encompassing surgery type, age, stage, and if was...
Abstract This retrospective study explored the changes in biomarkers indicators and prognosis COVID-19 patients with mental disorders (n = 60) from author’ Hospital between 2/13/2020 4/15/2020. Significant differences before after negative conversion were observed lymphocytes, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte aspartate aminotransferase, albumin, albumin/globulin direct bilirubin, alkaline phosphatase, uric acid, high-density lipoprotein cholesterol, ApoA1 (all P <...