A5061808375- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Dermatologic Treatments and Research
- Central Venous Catheters and Hemodialysis
- Photodynamic Therapy Research Studies
- Sympathectomy and Hyperhidrosis Treatments
- Intracranial Aneurysms: Treatment and Complications
- Aortic aneurysm repair treatments
- Coronary Interventions and Diagnostics
- Vascular Procedures and Complications
- Infectious Aortic and Vascular Conditions
- Nanoplatforms for cancer theranostics
- Acute Myocardial Infarction Research
- Porphyrin and Phthalocyanine Chemistry
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Angiogenesis and VEGF in Cancer
- Acute Ischemic Stroke Management
- Vascular anomalies and interventions
- Retinal Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Nietzsche, Schopenhauer, and Hegel
- Photoacoustic and Ultrasonic Imaging
Worcestershire Royal Hospital
2011-2023
Société Française de Cardiologie
2022
Worcestershire Acute Hospitals NHS Trust
2004-2020
National Health Service
2020
Heart of England NHS Foundation Trust
2017
University of Birmingham
2017
Cheltenham General Hospital
1996-2002
North Middlesex Hospital
1994-1999
University College London
1994-1999
Gloucestershire Royal Hospital
1998
anterior accessory saphenous vein ankle brachial index adjustable compression garments ambulatory phlebectomy Ambulatory Selective Varicose Ablation under Local anaesthesia Aberdeen Vein Questionnaire arteriovenous fistula body mass cyanoacrylate adhesive closure Clinical Etiological Anatomical Pathophysiological (classification) catheter directed foam sclerotherapy common femoral conservative haemodynamic treatment of venous incompetence in outpatients (= French acronym for ‘Cure...
Venous disease is the most common cause of leg ulceration. Although compression therapy improves venous ulcer healing, it does not treat underlying causes hypertension. Treatment superficial reflux has been shown to reduce rate recurrence, but effect early endovenous ablation on healing remains unclear.
One-year outcomes from the Early Venous Reflux Ablation (EVRA) randomized trial showed accelerated venous leg ulcer healing and greater ulcer-free time for participants who are treated with early endovenous ablation of lower extremity superficial reflux.To evaluate clinical cost-effectiveness reflux in patients ulceration.Between October 24, 2013, September 27, 2016, EVRA enrolled 450 (450 legs) ulceration less than 6 months' duration reflux. Initially, 6555 were assessed eligibility, 6105...
Colour duplex ultrasonographic imaging has largely replaced venography in the assessment of lower-limb venous disorders. This is a study use management patients with chronic ulceration community ulcer clinics. Patients leg and an ankle: brachial pressure index 0.85 or greater were studied. Assessment competence both deep superficial systems affected unaffected legs was performed using colour imaging. Reflux defined as reverse flow for than 1 s after manual calf compression. One hundred...
Although the management of atherosclerotic disease by use balloon angioplasty is widespread, treatment limited restenosis in 30% to 50% cases. Fibrocellular intimal hyperplasia, main cause restenosis, arises from proliferation and migration medial smooth muscle cells (SMC) into layer. Factors leading hyperplasia are incompletely understood, drugs have universally failed influence clinical restenosis. Photodynamic therapy (PDT), light activation photosensitizing generate cytotoxic mediators,...
Abstract Background Photodynamic therapy (PDT) reduces neointimal hyperplasia and negative remodelling following balloon injury in small large animal models. This clinical study investigated the role of adjuvant PDT femoral percutaneous transluminal angioplasty (PTA). Methods Eight PTAs seven patients (two women) with a median age 70 (range 59–86) years were performed PDT. All had previously undergone conventional at same site which resulted symptomatic restenosis or occlusion between 2 6...
To assess the outcome after transthoracic endoscopic sympathectomy (TES) for upper limb hyperhidrosis.Prospective cohort study.District general hospital.Consecutive patients undergoing TES hyperhidrosis over a fifteen month period.One-stage bilateral TES.Change in quality of life as shown by Short Form-36 health assessment questionnaire.Sixteen (11 women and 5 men, median age 26 years) underwent operation without complications. At follow-up 6.2 months, symptomatic improvement was found 32...
Background Venous ulceration is a common and costly health-care issue worldwide, with poor healing rates greatly affecting patient quality of life. Compression bandaging has been shown to improve reduce recurrence, but does not address the underlying cause, which often superficial venous reflux. Surgical correction reflux reduces ulcer recurrence; however, effect early endovenous ablation on unclear. Objectives To determine clinical effectiveness cost-effectiveness compression therapy...
Intraoperative thrombolysis was attempted in 31 acutely ischaemic legs after operative arteriography had demonstrated residual distal thrombus or occlusion following balloon-catheter thromboembolectomy. There were 30 patients, 16 men and 14 women, aged 43-82 (median 73) years. The indication for operation severe ischaemia with sensorimotor loss 25 limbs, failed percutaneous three acute graft three. A total of 21 perfemoral, 11 perpopliteal four embolectomies initially performed. Following...
Abstract Background Treatment of superficial venous reflux in addition to compression therapy accelerates leg ulcer healing and reduces recurrence. The aim this study was evaluate the costs cost-effectiveness early versus delayed endovenous treatment patients with ulcers. Methods This a within-trial cost-utility analysis 1-year time horizon using data from EVRA (Early Venous Reflux Ablation) trial. compared deferred ablation for truncal ulcer. outcome measure cost per quality-adjusted...
Objectives Venous thromboembolism is a potentially fatal complication of superficial endovenous treatment. Proper risk assessment and thromboprophylaxis could mitigate this hazard; however, there are currently no evidence-based or consensus guidelines. This study surveyed UK Republic Ireland vascular consultants to determine areas consensus. Methods A 32-item survey was sent via the Vascular Endovascular Research Network (phase 1). These results generated 10 statements which were...
Background Thermal ablation, usually performed with tumescent local anaesthesia (TLA), is the preferred method for varicose veins treatment. Tumescent always cited; however, little detail of procedure presented in publications. This retrospective audit clinical practice aims to provide detailed information on an important aspect endovenous practice. Methods Patients who underwent three types endothermal treatment (Venefit, Radiofrequency Induce Therapy and Endovenous Laser Ablation) a single...