A5016681513- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Effects of Exercise
- Gastric Cancer Management and Outcomes
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Colorectal and Anal Carcinomas
- Lung Cancer Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Hormonal Regulation and Hypertension
- Cardiovascular Function and Risk Factors
- Cardiac Fibrosis and Remodeling
- Cardiac Arrest and Resuscitation
- ECG Monitoring and Analysis
- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Heart Failure Treatment and Management
- Advancements in Semiconductor Devices and Circuit Design
- Soft tissue tumors and treatment
- Congenital heart defects research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Metastasis and carcinoma case studies
Hirosaki University
2014-2024
Nippon Medical School
2020
Otsuka (Japan)
2020
University of Alabama at Birmingham
2016-2018
To clarify the influence of hypertension and blood pressure (BP) control on thromboembolism major hemorrhage in patients with nonvalvular atrial fibrillation, a post hoc analysis J-RHYTHM Registry was performed.A consecutive series outpatients fibrillation enrolled from 158 institutions. Of 7937 patients, 7406 (70.8% men, 69.8±10.0 years) were followed for 2 years or until an event occurred. Hypertension defined as systolic BP ≥140 mm Hg, diastolic ≥90 history hypertension, and/or...
Although contact force (CF)-guided circumferential pulmonary vein isolation (CPVI) for paroxysmal atrial fibrillation (PAF) is useful, AF recurrence at long-term follow-up still remains to be resolved. The purpose of this study was assess safety and efficacy CF-guided CPVI compare residual conduction gaps during outcome between the conventional (non-CF-guided) CPVI.We studied 50 consecutive PAF patients undergoing by a ThermoCool EZ Steer catheter (conventional group, mean age 61 ± 10 years)...
Background:Wearable cardioverter-defibrillators (WCD) have been available in Japan since April 2014, but their application is still limited.Methods and Results:We report 9 patients with a WCD applied between September 2014. All were at high risk of life-threatening ventricular arrhythmias. During use, 1 patient had sustained tachycardia successful shock delivery; 6 (67%) subsequently underwent implantable cardioverter-defibrillator (ICD) therapy, while 2 no requirement because reduced risk,...
CartoSound™ (CS) module is useful in integrating 3-dimensional (3D) left atrial (LA) image with CT image. Integration method, however, has not been established. We reported the accuracy of LA electroanatomical (EA) and integration by registering roof (LAR) posterior wall (LAPW).The consecutive 56 fibrillation patients undergoing pulmonary vein isolation were studied. In initial 29 patients, before transseptal puncture, 3D CS LAR LAPW was created a mean 10 contour lines between right veins....
The parietal band is one of the muscle bands in right ventricle. This study investigated electrocardiographic and electrophysiological characteristics ablation outcome idiopathic ventricular arrhythmias (VAs) originating from band.We studied 14 patients with VA origins among 294 consecutive QRS morphologies VAs were characterized by a left bundle branch block inferior (n=12) or superior (n=2) axis pattern presence notch middle all cases, precordial transition at ≤lead V3 7 patients, slow...
Background: This study investigated the prevalence, electrocardiographic and electrophysiological characteristics, ablation outcome of idiopathic ventricular arrhythmias (VAs) originating from infundibular muscles (IFMs) in right ventricle consisting parietal band (PB) septal (SB). Methods Results: We studied 19 patients with VA origins PB 14 SB 5 among 294 consecutive ventricle. VAs exhibited left bundle branch block a inferior (n=12) or superior (n=2) axis (n=4) (n=1) pattern,...
Background: Regular exercise improves systolic cardiac dysfunction through Akt cascade-mediated physiological hypertrophy in congestive heart failure. Tissue acidosis impairs cascade, and coupling factor 6 induces tissue via activation of ecto-F1Fo complex. We tested the hypothesis that attenuates induced by its benefit mice. Methods results: Adult wild-type mice (n = 20) 6-overexpressing transgenic were divided into two groups with or without 4-week consisting 90-min swimming twice daily....
Low conduction velocity (CV) in the area showing low electrogram amplitude (EA) is characteristic of reentry circuit atypical atrial flutter (AFL). The quantitative relationship between CV and EA remains unclear. We characterized AFL right atrium (RA), focusing on local bipolar circuit.We investigated 26 RA (10 with typical AFL; 10 incisional 6 nonincisional AFL) using CARTO system. By referring to isochronal propagation maps delineated during AFL, points activated faster were selected...
Abstract Introduction Preferential conduction from an origin to breakout sites can occur during ventricular arrhythmias (VAs) originating the left papillary muscles (LVPMs). The purpose of this study was investigate incidence, electrophysiological characteristics, and relevance radiofrequency catheter ablation (RFCA) such a preferential demonstrated by pace mapping. Methods results We studied 34 consecutive patients undergoing RFCA 40 LVPM VAs. Among 78 QRS morphologies these VAs, mapping...
By using a noncontact mapping system, adenosine triphosphate (ATP)-sensitive atrial tachycardia (ATP-AT) originating from the atrioventricular (AV) node vicinity was successfully ablated at entrance to slow conduction zone indicated by manifest entrainment technique. We aimed prospectively validate efficacy of combination CARTO electroanatomical and in ablating this ATP-AT. Of 27 AT patients January 2013 March 2014, 6 with sustained ATP-AT were studied (age, 67±13 years; cycle length, 350±95...
Background Blood pressure (BP) variability has reportedly been a risk factor for various clinical events. To clarify the influence of BP visit‐to‐visit on adverse events in patients with nonvalvular atrial fibrillation, post hoc analysis J‐RHYTHM Registry was performed. Methods and Results Of 7406 outpatients fibrillation from 158 institutions, 7226 (age, 69.7±9.9 years; men, 70.7%), whom measured 4 times or more (14.6±5.0 times) during 2‐year follow‐up period until occurrence an event,...
Pulsed field ablation (PFA), a novel treatment for atrial fibrillation (AF), has yet to be evaluated in Japanese cohort.
Background Cavotricuspid isthmus‐dependent counterclockwise atrial flutter (typical AFL) is characterized by negative saw‐tooth morphology wave (F‐wave) in the inferior leads, which classified as type 1 with purely F‐wave without positive terminal deflection (PTD), 2 small PTD, and 3 broad PTD. The determinants of these morphological differences remain to be elucidated. Methods Results Of 72 patients (58 males, 65 ± 13 years) typical AFL, 19 were 53 types 3. We created an electroanatomic map...
During ventricular pacing, a fusion of atrial activation may occur owing to the simultaneous retrograde conduction atrioventricular (AV) node and accessory pathway (AP), potentially leading an inaccurate mapping AP insertion site.We tested hypothesis that landiolol, ultra-short-acting intravenous β1-blocker, could dissociate activation.We conducted prospective before-and-after study investigate effect landiolol on via AV AP. We enrolled 21 consecutive patients with orthodromic reciprocating...
Postpacing interval (PPI) measured after entrainment pacing describes the distance between site and reentrant circuit. However, influential features to PPI remain be elucidated.This study included 22 cases with slow/fast atrioventricular (AV) nodal tachycardia (AVNRT), 14 orthodromic AV reciprocating (AVRT) using an accessary pathway, typical atrial flutter (AFL), 18 other macroreentrant (atypical AFL). Rapid at a cycle length (PCL) 5% shorter than (TCL) was done from on or close reentry...
Abstract Background The Medtronic implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy with (CRT‐D) device is equipped the OptiVol fluid status monitoring system, which continuously measures intrathoracic impedance provides an early warning of thoracic retention, indicative decompensated heart failure (HF). accuracy telediagnosis HF this system still remains to be elucidated. Methods We studied 82 chronic patients implanted a ICD/CRT‐D (mean age 66±12 years, 62...