A5068083508- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Neurotransmitter Receptor Influence on Behavior
- Adrenal Hormones and Disorders
- Vitamin C and Antioxidants Research
- Sepsis Diagnosis and Treatment
- COVID-19 and Mental Health
- Hepatitis C virus research
- Nutritional Studies and Diet
- Natural Compounds in Disease Treatment
- Digital Mental Health Interventions
- Cannabis and Cannabinoid Research
- Pharmacological Receptor Mechanisms and Effects
- Osteoarthritis Treatment and Mechanisms
- Monoclonal and Polyclonal Antibodies Research
- Viral Infections and Outbreaks Research
- Liver Disease Diagnosis and Treatment
- Vitamin K Research Studies
- Hepatitis B Virus Studies
- Ferroptosis and cancer prognosis
- Healthcare professionals’ stress and burnout
- Mosquito-borne diseases and control
- Biological Activity of Diterpenoids and Biflavonoids
- Blood Pressure and Hypertension Studies
Nanjing University
2025
Purple Mountain Laboratories
2025
Hefei University
2025
Wuyi University
2025
University of British Columbia
2023-2024
Nanjing Medical University
2024
Jiangsu Province Hospital
2024
New York Academy of Sciences
2023
John Wiley & Sons (Germany)
2023
Moss Landing Marine Laboratories
2023
Abstract Background The clinical outcomes of COVID-19 patients in Hubei and other areas are different. We aim to investigate the epidemiological characteristics patient with Hunan which is adjacent Hubei. Methods In this double-center, observational study, we recruited all consecutive laboratory confirmed from January 23 February 14, 2020 two designated hospitals province, China. Epidemiological data patients’ electronic medical records were collected compared between mild, moderate...
Advanced and recurrent ovarian cancer has a poor prognosis is frequently resistant to numerous therapeutics; thus, safe effective drugs are needed combat this disease. Previous studies have demonstrated that triptolide (TPL) exhibits anticancer sensitization effects against cisplatin (DDP)‑resistant both in vitro vivo by inducing apoptosis; however, the involvement of autophagy induced TPL carcinoma remains unclear. In present study, results revealed facilitate SKOV3/DDP cell death. The...
Abstract We use a magnetron sputtering system to grow tantalum film on sapphire substrate with niobium buffer layer at room temperature. The is in $\alpha$-phase, which preferred for superconducting quantum devices. fabricate heavy fluxonium qubit this niobium-buffered film, demonstrates good performance. Forbidden transitions and sideband transition phenomena between specific energy levels are observed. Due the design parameters, described herein exhibits high anharmonicity while...
In recent years, significant progress has been made in the field of superconducting quantum circuits, particularly improving complexity processors for large-scale computing and simulation tasks. To enable execution information processing tasks on circuits containing millions qubits, it is essential to minimize thermal effects control measurement lines, ensuring that circuit components are qubits not significantly thermally excited. Recent studies have shown a quadrature-biased electro-optic...
Abstract Hyperalgesia, which often occurs in people suffering from alcohol use disorder, may drive excessive drinking and relapse. Emerging evidence suggests that the lateral habenula (LHb) play a significant role this condition. Previous research endocannabinoid signaling (eCBs) is involved drug addiction pain, LHb contains core components of eCBs machinery. We report here our findings rats subjected to chronic ethanol vapor exposure. detected substantial increase endocannabinoid-related...
Almost 40% of patients with kidney renal clear cell carcinoma (KIRC) advanced cancers eventually develop to metastases, and their 5-year survival rates are approximately 10%. Aberrant DNA methylations significantly associated the development KIRC. The aim our present study was identify suitable ferroptosis- immune-related (FI) biomarkers correlated aberrant improve prognosis diagnosis KIRC.ChAMP DESeq2 in R (3.6.2) were used screen differentially expressed methylation probes genes,...
Abstract In China, according to the ‘Technical Operating Procedures for Blood Stations (2019 Edition),’ blood stations are authorized utilize Chemiluminescence Immunoassay (CLIA) detect pathogen markers linked with transfusion-transmissible infections. However, currently, there is no approved CLIA reagent screening of blood-borne diseases in specifically detection Hepatitis B surface antigen. The objective this research project conduct a comprehensive evaluation performance Wantai...
Hypertension is a major risk factor for cardiovascular diseases in China; hence, identifying good serum markers might provide cost benefits terms of reducing morbidity rates. In this population-based case-control study, participants were recruited from five districts Hunan province, and 416 cases matched with an equal number controls. Markers related to elevated blood pressure assessed: Body Mass Index, total cholesterol, triglycerides, fasting glucose, creatinine. Three potential...
Abstract Background Novaferon, a novel protein drug approved for the treatment of chronic hepatitis B in China, exhibits potent antiviral activities. We aimed to determine anti-SARS-CoV-2 effects Novaferon vitro, and conducted randomized, open-label, parallel group study explore COVID-19. Methods In laboratory, inhibition on viral replication cells infected with SARS-CoV-2, SARS-CoV-2 entry into healthy was determined. Antiviral were evaluated COVID-19 patients plus Lopinavir/Ritonavir, or...
The current study aimed to explore the effects of microRNA (miR)‑145 on inflammatory response and oxidative stress (OS) in high glucose (HG)‑induced cardiomyocytes, as well specific mechanism underlying this action. H9c2 cells were treated with 33 mmol/l (HG group) or cotreated 24.5 mannitol 5.5 (hypertonic group), expression levels miR‑145 ADP ribosylation factor 6 (ARF6) detected. transfected pcDNA3.1‑ARF6, mimics corresponding negative controls prior assessment cell survival rate. Levels...
This study aimed to assess the efficacy of individual-donation nucleic acid testing (ID-NAT) in detecting occult hepatitis B virus infection (OBI) among anti-HBc positive blood donors, compared minipool (MP-NAT).The present analyzed data from Shandong Blood Center China during period January 2018 June 2022, where HBsAg-negative donors were screened using 6-sample (6-sample MP NAT) method. NAT-positive samples underwent subsequent and anti-HBs testing. Approximately 5000 that passed mixing...
Epithelial ovarian cancer (EOC) is a fatal gynecological malignancy with limited therapeutic options. Previous research has demonstrated that Tripterygium glycosides (GTW) can enhance effectiveness of cisplatin (DDP) chemotherapy against EOC. However, the underlying mechanism GTW alleviating EOC still remains unclear. In this article, an ID8 cell-derived xenograft mouse model was established to evaluate anti-tumor efficacy combined DDP. Consistent previous findings, results suggested DDP...