- Biofuel production and bioconversion
- Catalysis for Biomass Conversion
- Cancer Genomics and Diagnostics
- Thermochemical Biomass Conversion Processes
- Lignin and Wood Chemistry
- Genetics, Bioinformatics, and Biomedical Research
- Health and Medical Research Impacts
- Biodiesel Production and Applications
- Advanced Cellulose Research Studies
- Catalysis and Hydrodesulfurization Studies
- Genetic Mapping and Diversity in Plants and Animals
- Plant Pathogens and Resistance
- interferon and immune responses
- GABA and Rice Research
- Microbial Fuel Cells and Bioremediation
- Cancer-related molecular mechanisms research
- Plant Pathogens and Fungal Diseases
- Plant-Microbe Interactions and Immunity
- Plant Stress Responses and Tolerance
- Microbial Metabolic Engineering and Bioproduction
- Electrochemical sensors and biosensors
- Algal biology and biofuel production
- Drug Solubulity and Delivery Systems
- Enzyme Catalysis and Immobilization
- Rice Cultivation and Yield Improvement
Xuzhou Medical College
2015-2025
University of Maryland, College Park
2025
Park University
2025
First People's Hospital of Jingzhou
2025
Yangzhou University
2025
Guangdong Academy of Sciences
2022-2024
Rice Research Institute
2018-2024
Guangdong Academy of Agricultural Sciences
2018-2024
Johns Hopkins University
2009-2024
Ministry of Agriculture and Rural Affairs
2022-2024
Abstract The INDUCER OF CBF EXPRESSION (ICE)–C-REPEAT BINDING FACTOR/DRE FACTOR1 (CBF/DREB1) transcriptional pathway plays a critical role in modulating cold stress responses Arabidopsis thaliana. Dissecting crucial upstream regulatory signals or components of the ICE-CBF/DREB1 cascade will enhance our understanding plant cold-tolerance mechanisms. Here, we show that jasmonate positively regulates to freezing Arabidopsis. Exogenous application significantly enhanced tolerance with without...
To understand the effect of torrefaction severity on structure changes hemicellulose, cellulose, lignin and their subsequent catalytic fast pyrolysis (CFP) behavior, lignin, cellulose was performed in a tubular reactor with different reaction temperatures (210–300 °C) residence times (20–60 min). The experimental results show that rank order thermal stability during > hemicellulose. torrefied hemicelulose, were subsequently catalytic-fast-pyrolyzed over HZSM-5 semi-batch pyroprobe reactor....
Age-associated central arterial wall stiffness is linked to extracellular matrix remodeling, including fibrosis and vascular calcification. Angiotensin II induces both metalloproteinase 2 (MMP2) calpain-1 expression activity in the wall. However, role of MMP2 activation remodeling remains unknown. Dual histo-immunolabeling demonstrates colocalization within old rat smooth muscle cells. Overexpression transcripts, protein levels, activity, part, by increasing ratio membrane type 1 MMPs tissue...
Aerobic photocatalysis generates ROS to oxidise HMF into DFF and FDCA with co-production of H 2 O that potentially induce over-oxidation. Anaerobic enables ambient oxidation simultaneous HER, or hydrogenation BHMF.
Angiotensin II (Ang II) signaling, including matrix metalloproteinase type (MMP2) activation, has been linked to an age-associated increase in migration capacity of vascular smooth muscle cells (VSMC), and other proinflammatory features arterial aging. Calpain-1 activation is required for MMP2 expression fibroblasts induced cardiomyocytes by Ang II. The consequences engagement calpain-1 with its substrates, however, governing the status within wall, remains unknown.The present findings...
Advancing age induces aortic wall thickening that results from the concerted effects of numerous signaling proteins, many which have yet to be identified. To search for novel proteins associated with thickening, we performed a comprehensive quantitative proteomic study analyze young (8 months) and old (30 rats identified 50 significantly change in abundance aging. One protein, milk fat globule protein epidermal growth factor 8 (MFG-E8), increases 2.3-fold aorta. Transcription translation...
An accumulation of milk fat globule EGF-8 protein (MFG-E8) occurs within the context arterial wall inflammatory remodeling during aging, hypertension, diabetes mellitus, or atherosclerosis. MFG-E8 induces VSMC invasion, but whether it affects proliferation, a salient feature inflammation, is unknown. Here, we show that in rat vivo, PCNA and Ki67, markers cell cycle activation, increase with age between 8 30 months. In fresh early passage isolated from old aortae, an CDK4 PCNA, acceleration S...
Age-associated arterial remodeling involves wall collagen deposition and elastin fragmentation, as well an increase in pressure. This is linked to proinflammatory signaling, including transforming growth factor-β1, monocyte chemoattractant protein 1, proendothelin activated by extracellular matrix metalloproteinases (MMPs) orchestrated, part, the transcriptional factor ets-1. We tested hypothesis that inhibition of MMP activation can decelerate age-associated proinflammation its attendant...
Mediator of IRF3 activation (MITA), also known as stimulator interferon genes (STING), plays a vital role in the innate immune responses to cytosolic dsDNA. The trafficking MITA from ER perinuclear vesicles is necessary for its downstream molecules, which lead production interferons and pro-inflammatory cytokines. However, exact mechanism remains elusive. Here, we report that transmembrane emp24 protein transport domain containing 2 (TMED2) potentiates DNA virus-induced signaling....