A5101859366- Lung Cancer Treatments and Mutations
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Neonatal Respiratory Health Research
- Cardiovascular Health and Disease Prevention
- Occupational exposure and asthma
- Cardiac Ischemia and Reperfusion
- Occupational and environmental lung diseases
- Chemical Synthesis and Analysis
- Real-time simulation and control systems
- Cellular Mechanics and Interactions
- Respiratory Support and Mechanisms
- Healthcare and Venom Research
- Curcumin's Biomedical Applications
- Mechanical Circulatory Support Devices
- Electrospun Nanofibers in Biomedical Applications
- Exercise and Physiological Responses
- Medicinal Plants and Bioactive Compounds
- Circular RNAs in diseases
- Alcohol Consumption and Health Effects
- Cloud Data Security Solutions
- HER2/EGFR in Cancer Research
- Advanced Sensor and Control Systems
- Eicosanoids and Hypertension Pharmacology
- Hemostasis and retained surgical items
Shaanxi Provincial People's Hospital
2022
Xinyu University
2014-2022
The First People's Hospital of Zhaoqing
2021
Guangdong Food and Drug Vocational College
2012-2018
Shenyang Agricultural University
2018
Xi'an Jiaotong University
2018
Chengdu Third People's Hospital
2013-2017
Chongqing Medical University
2016-2017
North China Electric Power University
2014
Zhongnan Hospital of Wuhan University
2008
Epithelial to mesenchymal transition (EMT) in alveolar epithelial cells (AECs) has been widely observed patients suffering interstitial pulmonary fibrosis. In vitro studies have also demonstrated that AECs could convert into myofibroblasts following exposure TGF-β1. this study, we examined whether EMT occurs bleomycin (BLM) induced fibrosis, and the involvement of bronchial (BECs) EMT. Using an α-smooth muscle actin-Cre transgenic mouse (α-SMA-Cre/R26R) strain, labelled vivo. We performed a...
Lack of specific and efficient therapy leads to the high mortality rate acute lung injury (ALI) respiratory distress syndrome (ARDS). Losartan is a potent pharmaceutical drug for ALI/ARDS. However, protective effects mechanisms losartan remain incompletely known. This study evaluates on ALI/ARDS further investigates possible these effects. Mice received i.p. injections AT1 inhibitor (15 mg/kg), or control vehicle, half hour after cecal ligation puncture (CLP). Plasma TNF-α, IL-1β, IL-6...
Pulmonary fibrosis (PF) is a life-threatening interstitial lung disease. In this study, we tried to reveal the model of action between high-mobility group box 1 (HMGB1) and α-smooth muscle actin (α-SMA) protective role gefitinib in pulmonary induced by administration bleomycin aerosol mice. For mechanism tissues were harvested two weeks after modeling detect coexpression HMGB1 α-SMA immunohistochemistry immunofluorescence staining. Protein-DNA interactions analyzed using pulldown assay study...
Breast carcinomas show a trend toward bone metastasis that is prevalent worldwide. Celecoxib (CX) and minocycline hydrochloride (MH) have both been widely used in treating breast cancer; however, their combined effects on the osseous of cancer not yet studied. In present study, cells were injected into back femoral nude mice, CX MH intraperitoneally administered every other day at doses 30 40 mg/kg/day, respectively, for days. Tumor weights volumes significantly lower tumor inhibition rate...
Reperfusion therapy is the most crucial strategy for rescuing ischemic myocardium and reducing infarction size. Cyclosporine A (CsA) can protect against reperfusion-induced myocardial necrosis. However, clinical effects of CsA on (MI) remain uncertain. This study investigated reperfusion injury (RI) in MI. We searched included articles regarding randomized controlled trials investigating effect patients with MI from PubMed, EMBASE, Cochrane Library databases an analysis. then performed...
Abstract Background: Rheumatoid arthritis (RA) is a chronic articular synovial inflammatory disease. The precise etiology underlying the pathogenesis of RA remains unknown. We aimed to investigate inhibitory effect curcumin analog FM0807 (curcumin salicylate monoester, 2-hydroxy-, 4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxo-1,6-heptadien-1-yl]-2-methoxyphenyl ester) on experimental and its possible mechanisms action. Method: Rats with Freund’s complete adjuvant (FCA)-induced (AIA)...
Hemostatic materials are generally applied in surgical operations for cancer, but their effects on the growth and recurrence of tumors unclear. Herein, three commonly used naturally derived hemostatic materials, gelatin sponge, Surgicel (oxidized regenerated cellulose), biopaper (mixture sodium hyaluronate carboxymethyl chitosan), were cocultured with A549 human lung adenocarcinoma cells vitro. Furthermore, performance tumorigenicity cells observed after subcutaneous implantation into...
This study investigated the effects of polysaccharides from root Codonopsis pilosula (PCP) on physical fatigue induced by forced swimming in mice. The mice were divided into five groups, i.e., one control group and four PCP-treated groups. was given distilled water groups different doses PCP (100, 200, 400, 800 mg/kg). After 28 days, anti-fatigue assessed using test, exhaustive times, blood lactic acid (BLA), serum urea nitrogen (SUN), liver glycogen muscle measured. data showed that could...
This paper is based on the security of application software operating system as breakthrough point, aiming at problems Linux system. The mandatory access control, rules and mechanisms policy are emphatically analyzed, including configuration process in detail to ensure
In this paper, we discuss the applications of UC/OS-II and DSP(digital signal processor) in area harmonic analyzing. research, FFT algorithm is employed, realization on DSP discussed. The whole system based operation system, which coordinate all tasks about system. DSP+ARM improve reliability real time quality. hardware design software are proposed with flow chart part routine codes shown.
Objective To investigate the effect of down-regulating epidermal growth factor receptor (EGFR) expression on Bleomycin induced pulmonary fibrosis in mice.Methods Forty 4 ～6 week aged C57BL/c male mice were randomly divided into control,bleomycin,bleomycin plus EGFR RNAi groups and negative control group.Bleomycin group treated with bleomycin (3 mg/kg) by endotracheal injection day 0,control PBS.And received EGRF siRNA intratracheal administration.RNAi administration.Mice sacrificed 10 days...