A5043060412- Oral microbiology and periodontitis research
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Immune Response and Inflammation
- Biosensors and Analytical Detection
- Renal and related cancers
- Cancer Genomics and Diagnostics
- Marine and coastal ecosystems
- Salivary Gland Disorders and Functions
- Glycosylation and Glycoproteins Research
- E-Government and Public Services
- Monoclonal and Polyclonal Antibodies Research
- Immunotherapy and Immune Responses
- Streptococcal Infections and Treatments
- Marine Toxins and Detection Methods
- Genetic factors in colorectal cancer
- Genetic Syndromes and Imprinting
- Cancer, Hypoxia, and Metabolism
- T-cell and B-cell Immunology
- Epigenetics and DNA Methylation
- Biochemical and Molecular Research
- Chemical Synthesis and Analysis
- Heat shock proteins research
- Cell Adhesion Molecules Research
- Colorectal Cancer Screening and Detection
Palm Springs General Hospital
2024
Mass General Brigham
2020-2022
Florida Institute of Technology
2018-2021
Harvard University
2020
Spaulding Rehabilitation Hospital
2020
Anglia Ruskin University
2015
AstraZeneca (United Kingdom)
2012-2013
University of North Dakota
2006-2010
Boston Medical Center
2010
Boston University
2010
Journal Article Analysis of the genomic sequence for autosomal dominant polycystic kidney disease (PKD1) gene predicts presence a leucine-rich repeat: The AMERICAN PKD1 Consortium (APKD1 Consortium) Get access Timothy C. Burn, Burn Search other works by this author on: Oxford Academic PubMed Google Scholar D. Connors, Connors William R. Dackowski, Dackowski Linda Petry, Petry Terence J. van Raay, Raay John M. Millholland, Millholland Marc Venet, Venet Glenn Miller, Miller Ramond Hakim, Hakim...
Goal: The aim of the study herein reported was to review mobile health (mHealth) technologies and explore their use monitor mitigate effects COVID-19 pandemic. Methods: A Task Force assembled by recruiting individuals with expertise in electronic Patient-Reported Outcomes (ePRO), wearable sensors, digital contact tracing technologies. Its members collected discussed available information summarized it a series reports. Results: identified that could be deployed response pandemic would likely...
Background & Aims: The optimal strategy for the detection of hereditary nonpolyposis colorectal cancer (HNPCC) gene carriers remains uncertain. We evaluated whether microsatellite instability (MSI) analysis or MSH2 and MLH1 protein immunostaining tumors will screen individuals efficiently germline testing. Methods: performed a case-series study 114 eligible families enrolled in our high-risk (CRC) registry. Medical history data were collected on probands relatives. MSI was proband tumors,...
The objective of this research was to determine whether gram-negative bacteria frequently isolated from periodontally diseased sites contained polyclonal B-cell activators. Polyclonal activation, which results in nonspecific activation multiple clones analyzed by a hemolysis-in-gel assay designed detect broad range antibody specificities. Extracts numerous bacterial strains, including Bacteroides gingivalis, melaninogenicus subsp. melaninogenicus, B. intermedius, Fusobacterium nucleatum,...
Abstract Purpose: Endosialin/CD248/tumor endothelial marker 1 is expressed in stromal cells, and pericytes various tumors; however, few studies have focused on expression malignant cells. Experimental Design: We studied of endosialin clinical specimens, cell culture, animal models designed an anti-endosialin therapeutic prototype. Results: Fifty human tumor lines 6 normal types culture were assayed by reverse transcription-PCR and/or flow cytometry for endosialin. Cell surface protein was...
COVID-19 has resulted in significant morbidity and mortality worldwide. Lateral flow assays can detect anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) antibodies to monitor transmission. However, standardized evaluation of their accuracy tools aid interpreting results are needed.We evaluated 20 IgG IgM selected from available tests April 2020. We the assays' performance using 56 pre-pandemic negative SARS-CoV-2-positive plasma samples, collected 10-40 days after symptom...
We previously reported the isolation of a 2.5 Mb tumor-suppressing subchromosomal transferable fragment (STF) from human chromosome 11p15 and identification nine known genes four novel within this STF. now report two cDNAs, designated here as TSSC4 TSSC6 (tumor-suppressing STF cDNA 4 6), located encode predicted proteins 329 290 amino acids, respectively, with no close similarity to proteins. are both in center 1 imprinted domain, which contains TSSC3, TSSC5, p57(KIP2), KVLQT1, ASCL2, IGF2...
Cellular responses of young adults with severe periodontitis (SP) were compared to the cellular a healthy periodontium (HP). Analyses included T‐cell and B‐cell levels, blast transformation, production leukocyte inhibitory factor (LIF), phagocytosis killing by peripheral polymorphonuclear leukocytes (PMN's). The levels T‐ B‐cells virtually identical in HP SP groups. In blastogenesis assays subjects tended respond bacterial extracts more frequently than did although differences frequency not...
Abstract The immunosuppressive activity of glycerol teichoic acid extracts isolated from Streptococcus pyogenes 1-RP41, a group A beta hemolytic streptococcus, has been investigated by measuring the number direct plaque-forming cells and indirect in spleen serum hemolysin titers mice treated with acid. These caused significant suppression both IgM IgG response which was evident at organ level circulating antibody level. Inhibition immune seemed to be function poly(glycerolphosphate) backbone...
Appendiceal mucinous neoplasms (AMNs) are uncommon gastrointestinal tumors characterized by mucus accumulation in the appendix. Patients may complain of acute appendicitis-like symptoms with other alarming features, but approximately half cases AMNs found incidentally on imaging. Early diagnosis and management these important to prevent malignant progression complications such as bowel obstruction pseudomyxoma peritonei. We report a case 28-year-old female who initially presented vomiting...
T he purposes of this study were two‐fold : to compare the DNA probe and enzyme linked immunosorbent assay (ELISA) microbial identification tests correlate levels microorganisms with adult periodontitis. A single plaque sample was taken from each 2 sites in 52 patients. Twelve these patients also sampled during after treatment. The experimental site had clinical indicators disease (bleeding on probing, probing attachment loss ≥ 6 mm) contralateral (control) clinically healthy. total 176...
Inshore-offshore migration occurs frequently in seahorse species either because of prey opportunities or it is driven by reproduction, and variations water temperature may dramatically change migratory behavior physiology. The present study investigated the behavioral physiological responses lined Hippocampus erectus under thermal stress evaluated potential effects different temperatures on its reproduction. results showed that tolerance seahorses was time dependent. Acute (30°C, 2–10 hours)...