- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Bone and Dental Protein Studies
- Mechanical Circulatory Support Devices
- Vaccine Coverage and Hesitancy
- Ideological and Political Education
- Influenza Virus Research Studies
- Cardiac Arrest and Resuscitation
- HIV, Drug Use, Sexual Risk
- COVID-19 Clinical Research Studies
- Health disparities and outcomes
- Viral Infections and Outbreaks Research
- Cardiac Ischemia and Reperfusion
- Connexins and lens biology
- Enhanced Recovery After Surgery
- Nanoparticles: synthesis and applications
- EFL/ESL Teaching and Learning
- Geochemistry and Elemental Analysis
- Protein Hydrolysis and Bioactive Peptides
- Insect and Arachnid Ecology and Behavior
- dental development and anomalies
- COVID-19 and Mental Health
- Data-Driven Disease Surveillance
- Global trade and economics
- Infant Nutrition and Health
Fudan University
2019-2024
Tianjin Foreign Studies University
2024
Jinan City People's Hospital
2023
Shandong First Medical University
2023
Shaanxi Normal University
2018-2023
Institute of Zoology
2018-2023
Xi'an International Studies University
2023
State Key Laboratory of Pollution Control and Resource Reuse
2021-2022
Nanjing University
2009-2022
Changsha University of Science and Technology
2012-2022
Intense nonpharmaceutical interventions were put in place China to stop transmission of the novel coronavirus disease 2019 (COVID-19). As intensifies other countries, interplay between age, contact patterns, social distancing, susceptibility infection, and COVID-19 dynamics remains unclear. To answer these questions, we analyze survey data for Wuhan Shanghai before during outbreak contact-tracing information from Hunan province. Daily contacts reduced seven- eightfold distancing period, with...
Microplastics are widespread in freshwater environments, their biological effects and combined of other pollutants have attracted extensive attention. In this study, we investigated the adsorption properties heavy metals onto polystyrene (PS) microplastics as well bioavailability toxicity by hydroponic wheat seedlings experiment. Results showed that PS (0.5 µm, 100 mg/L) had no significant effect on growth, photosynthesis, reactive oxygen species (ROS) content. However, could adsorb copper...
COVID-19 vaccination is being conducted in over 200 countries and regions to control SARS-CoV-2 transmission return a pre-pandemic lifestyle. However, understanding when non-pharmaceutical interventions (NPIs) can be lifted as immunity builds up remains key question for policy makers. To address this, we built data-driven model of China. We estimated that, prevent the escalation local outbreaks widespread epidemics, stringent NPIs need remain place at least one year after start vaccination....
Abstract East Asia is as a principal hotspot for emerging zoonotic infections. Understanding the likely pathways their emergence and spread requires knowledge on human-human human-animal contacts, but such studies are rare. We used self-completed interviewer-completed contact diaries to quantify patterns of these contacts 965 individuals in 2017/2018 high-income densely-populated area China, Shanghai City. Interviewer-completed recorded more social (19.3 vs. 18.0) longer duration (35.0 29.1...
Corporate green innovation is an effective way to achieve energy conservation and emission reduction. Enterprises’ willingness pursue increasingly affected by external factors. By using a quasi-natural experiment of China’s Stock Connect program, we investigate the impact stock market liberalization on corporate innovation. We find that increases enterprises’ innovation, especially for state-owned enterprises. also plays stronger role in promoting invention patents enterprises whose managers...
ABSTRACT Background Human contact patterns are a key determinant driving the spread of respiratory infectious diseases. However, relationship between and seasonality as well their possible association with diseases is yet to be clarified. Methods We investigated temperature human using data collected through cross‐sectional diary‐based survey in Shanghai, China, December 24, 2017, May 30, 2018. then developed compartmental model influenza transmission informed by derived seasonal trends...
Cancer survival among adolescents and young adults (AYAs) was previously reported as showing little or no improvement compared to younger older counterparts. The role of the HIV/AIDS epidemic in AYA deficit has not been evaluated.Using cancer registry data from Surveillance, Epidemiology, End Results program (SEER 9), we examined sex-specific 5-year relative trends for children (0-14 years old), AYAs (15-39 (40 older) diagnosed with during 1973-2009 followed through end 2014. analysis...
China has experienced a COVID-19 wave caused by Omicron XBB variant starting in April 2023. Our aim is to conduct retrospective analysis exploring the dynamics of outbreak under counterfactual scenarios that combine use vaccines, antiviral drugs, and nonpharmaceutical interventions.
Abstract Background Assessing the measles immunity profile is critical for developing effective nationwide or region-wide supplementary immunization activities (SIAs). This study aims to assess population levels in China and investigate factors contributing age-specific heterogeneities. Methods We conducted a cross-sectional population-based serological southern between June October 2021. determined mean antibody concentration seroprevalence by age over time, along with their associated...
Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction that occurs secondary to infection in the body without overt central nervous system (CNS) infection. SAE frequently encountered critically ill patients intensive care units and can be detected up 50-70% of septic patients. Previous studies have demonstrated inflammatory cytokine release oxidative stress injury are major pathophysiological mechanisms However, there no effective strategies for treatment SAE. Insulin has...
Abstract Background Extra-Corporeal Membrane Oxygenation (ECMO) therapy is associated with high risk of neurologic injury. But the mechanism injury during and/or after ECMO still unclear. Recent animal experiments confirmed that treatment increases immune inflammatory response. The aim this study to investigate effect VV- on response cerebral tissues and neurological impairment. Methods 18 porcine were randomly divided into control, sham group (n = 6/group). was run 24 h in group, serum...
Pulmonary changes in veno-venous extracorporeal membrane oxygenation (VV-ECMO) are rarely determined. We compared the contribution of VV-ECMO and cannulation based on observation pulmonary inflammatory reaction parenchymal construction a porcine model low tidal volume (VT) ventilation. also evaluated effect adding continuous renal replacement therapy (CRRT) to ECMO circuit, because CRRT is known reduce systemic cytokine release induced by VV-ECMO. A total 18 pigs undergoing low-VT...
Abstract Background To allow a return to pre-COVID-19 lifestyle, virtually every country has initiated vaccination program mitigate severe disease burden and control transmission. However, it remains be seen whether herd immunity will within reach of these programs. Methods We developed data-driven model SARS-CoV-2 transmission for China, population with low prior from natural infection. The is calibrated considering COVID-19 history the estimated transmissibility Delta variant. Three...
The coronavirus disease 2019 (COVID-19) pandemic and the measures taken by authorities to control its spread have altered human behavior mobility patterns in an unprecedented way. However, it remains unclear whether population response a COVID-19 outbreak varies within city or among demographic groups. Here, we utilized passively recorded cellular signaling data at spatial resolution of 1 km × for over 5 million users epidemiological surveillance collected during severe acute respiratory...
ABSTRACT Objective The outbreak of novel coronavirus disease 2019 (COVID-19) imposed a substantial health burden in mainland China and remains global epidemic threat. Our objectives are to assess the case fatality risk (CFR) among COVID-19 patients detected China, stratified by clinical category age group. Methods We collected individual information on laboratory-confirmed cases from publicly available official sources December 29, February 23, 2020. explored factors associated with...
Abstract Amelotin is expressed and secreted by ameloblasts in tooth development, but amelotin distribution during enamel development not clear. In this report, we first investigated expression developing teeth immunohistochemistry. was detected the matrix at secretion maturation stages of development. also observed Tomes' processes on apical ends secretory ameloblasts. We then compared gene with those amelogenin, enamelin, ameloblastin mandibles postnatal mice RT‐PCR. The as early day 0...
Abstract Hypercatabolism is common under septic conditions. Skeletal muscle the main target organ for hypercatabolism, and this phenomenon a vital factor in deterioration of recovery patients. In skeletal muscle, activation ubiquitin-proteasome system plays an important role hypercatabolism status. Insulin anticatabolic hormone previous evidence suggests that insulin administration inhibits various steps system. However, whether can alleviate degradation protein by inhibiting condition...
Social contact patterns significantly influence the transmission dynamics of respiratory pathogens. Previous surveys have quantified human social patterns, yielding heterogeneous results across different locations. However, significant gaps remain in understanding rural areas China. We conducted a pioneering study to quantify Anhua County, Hunan Province, China, from June October 2021, when there were minimal coronavirus disease-related restrictions area. Additionally, we simulated epidemics...