A5100453879- COVID-19 epidemiological studies
- Pancreatic and Hepatic Oncology Research
- Carcinogens and Genotoxicity Assessment
- Hepatocellular Carcinoma Treatment and Prognosis
- COVID-19 Clinical Research Studies
- Ovarian cancer diagnosis and treatment
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Neuroendocrine Tumor Research Advances
- SARS-CoV-2 and COVID-19 Research
- Glutathione Transferases and Polymorphisms
- Venous Thromboembolism Diagnosis and Management
- Vascular anomalies and interventions
- Circular RNAs in diseases
- Peripheral Artery Disease Management
- Nosocomial Infections in ICU
- Advanced Text Analysis Techniques
- Educational Technology and Pedagogy
- Cancer-related molecular mechanisms research
- Viral Infections and Outbreaks Research
- MRI in cancer diagnosis
- Vascular Procedures and Complications
- Clinical Laboratory Practices and Quality Control
- Lexicography and Language Studies
- Ultrasound and Hyperthermia Applications
Huashan Hospital
2014-2023
Fudan University
2009-2023
Dalian Naval Academy
2021
Huadong Hospital
2006-2020
Capital Medical University
2017
The First Affiliated Hospital, Sun Yat-sen University
2017
Zhongshan Hospital
2011-2017
Sun Yat-sen University
2017
Beijing Ditan Hospital
2017
Zhengzhou University
2010-2011
COVID-19 vaccination is being conducted in over 200 countries and regions to control SARS-CoV-2 transmission return a pre-pandemic lifestyle. However, understanding when non-pharmaceutical interventions (NPIs) can be lifted as immunity builds up remains key question for policy makers. To address this, we built data-driven model of China. We estimated that, prevent the escalation local outbreaks widespread epidemics, stringent NPIs need remain place at least one year after start vaccination....
To assess the case fatality risk (CFR) of COVID-19 in mainland China, stratified by region and clinical category, estimate key time-to-event intervals.We collected individual information aggregated data on cases from publicly available official sources 29 December 2019 to 17 April 2020. We accounted for right-censoring CFR explored factors mortality. fitted Weibull, gamma, log-normal distributions using maximum-likelihood estimation.We analyzed 82 719 laboratory-confirmed reported including...
High mobility group box 1 (HMGB1) and HMGB2 overexpression has been observed in several human tumor types, is involved cancer progression prognosis. However, the clinicopathological significance of HMGB1 expression bladder carcinoma (BCa), particularly involvement these proteins angiogenesis, remains unclear. In present study, immunohistochemistry real-time polymerase chain reaction (PCR) 64 BCa patients revealed that were overexpressed tissues compared with normal tissues, correlated...
Vinyl chloride monomer (VCM) is a colorless gas under room temperature and has been mostly used to produce polyvinyl (PVC) since the 1970s. It classified by International Agency of Research on Cancer (IARC) as known human carcinogen (Group 1). In this study, genetic damage in VCM workers was evaluated relation their occupational cumulative exposure VCM.Cytokinesis-block micronucleus assay conducted 229 138 controls detect chromosome peripheral blood lymphocytes. The dose (CED) calculated...
ABSTRACT Objective The outbreak of novel coronavirus disease 2019 (COVID-19) imposed a substantial health burden in mainland China and remains global epidemic threat. Our objectives are to assess the case fatality risk (CFR) among COVID-19 patients detected China, stratified by clinical category age group. Methods We collected individual information on laboratory-confirmed cases from publicly available official sources December 29, February 23, 2020. explored factors associated with...
Objective: To evaluate whether polymorphisms in metabolizing enzymes contributed to susceptibility of chromosomal damage induced by vinyl chloride monomer (VCM). Methods: Cytokinesis block micronucleus test was performed on 185 VCM-exposed workers and 41 control subjects detect peripheral lymphocytes. The polymerase chain reaction restriction fragment length polymorphism technique applied GSTT1, GSTM1, GSTP1G/A, CYP2E1G/C, CYP2D6G/C. Poisson regression analysis performed. Results: Sex, age,...
Objective: To evaluate whether base excision repair gene polymorphisms contributed to susceptibility of chromosomal damage induced by vinyl chloride monomer (VCM). Methods: Cytokinesis block micronucleus test was performed on 185 VCM-exposed workers detect in peripheral lymphocytes. The PCR-restriction fragment length polymorphism technique applied TDG, PARP1, and APE1 genes. Univariate multivariate Poisson regression analysis performed. Results: There a 1.198-fold increased frequency for...
Purpose: To evaluate therapeutic efficacy of ultrasound (US)-guided high-intensity focused (HIFU) ablation for treatment needle-track seeding hepatocellular carcinoma (HCC).Materials and methods: Nine patients with HCC were treated as outpatients using US-guided HIFU ablation. The mean size the lesion was 1.8 cm (range 1.1 to 2.6 cm), two lesions located on abdominal wall, seven chest wall. An acoustic power 200 400 W used determined by echo changes after energy exposures, intermittent...
COVID-19 vaccination is being conducted in over 190 countries/regions to control SARS-CoV-2 transmission and return a pre-pandemic lifestyle. However, understanding when non-pharmaceutical interventions (NPIs) can be lifted as immunity builds up remain key question for policy makers. To address it, we built data-driven model of China. We estimated that prevent the escalation local outbreaks widespread epidemics, stringent NPIs need place at least one year after start vaccination. Should...
Objective To investigate the relationship between EphA2, EphrinAl and E-cadherin expressions tumor stage prognosis in pancreatic cancer. Method Ecadherin were detected by immunohistochemistry tissue normal specimens from 48 patients with primary Results The of EphA2 higher carcinoma tissues than (P<0. 05). expression was lower cancer With decreasing histological differentiation, increased significantly 05), while decreased positive stageⅢ Ⅳ Ⅰ Ⅱ (47. 9%vs 6. 25% , P<0. 05;47. 9% vs 8. 3%,...
Verbs are important in semantic understanding of natural language. Traditional verb representations, such as FrameNet, PropBank, VerbNet, focus on verbs' roles. These roles too coarse to represent semantics. In this paper, we introduce patterns semantics, that each pattern corresponds a single the verb. First analyze principles for patterns: generality and specificity. Then propose nonparametric model based description length. Experimental results prove high effectiveness patterns. We...
Objective To establish the target measurement uncertainty(MU) of routine coagulation assay according to External Quality Assessment data (EQA) assay. Methods Beijing Center for Clinical Laboratory (BCCL) established measurementuncertainty assayswith theup-downmethodon basis 93 clinical laboratoriesEQA datain BeijingThese assays includedActivated partial thromboplastine time(APTT), Fibrinogen(FBG), International Normalized Ratio(INR), Prothrombin time(PT), Thrombin time(TT) and...