Jun Chen

ORCID: 0000-0002-8623-7732
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About
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Research Areas
  • Lipid metabolism and biosynthesis
  • Plant biochemistry and biosynthesis
  • Amino Acid Enzymes and Metabolism
  • Insect symbiosis and bacterial influences
  • Genetic Mapping and Diversity in Plants and Animals
  • Peroxisome Proliferator-Activated Receptors
  • Legume Nitrogen Fixing Symbiosis
  • Genomics and Phylogenetic Studies
  • Plant tissue culture and regeneration
  • Plant and animal studies
  • Cardiac Ischemia and Reperfusion
  • Agricultural Systems and Practices
  • Cancer, Lipids, and Metabolism
  • Plant-Microbe Interactions and Immunity
  • Insect Resistance and Genetics
  • Cholesterol and Lipid Metabolism
  • Nitric Oxide and Endothelin Effects
  • Biochemical Acid Research Studies
  • Biological and pharmacological studies of plants
  • Photosynthetic Processes and Mechanisms
  • Plant Molecular Biology Research
  • Antibiotic Resistance in Bacteria
  • Eicosanoids and Hypertension Pharmacology
  • Insect and Pesticide Research
  • Plant Micronutrient Interactions and Effects

East China University of Technology
2019-2024

Wuhan Polytechnic University
2021

Central South University of Forestry and Technology
2019

Central South University
2019

South China Agricultural University
2018

Institute of Hydrobiology
2017

University of Chinese Academy of Sciences
2017

Huazhong Agricultural University
2017

Academy of Military Medical Sciences
2016

Dartmouth College
1999

Crop and aquatic animal co-culture systems have been used for over 1200 years can very efficiently utilize nutrients materials available in agroecology settings. These are sustainable forms of agriculture, extensively practiced worldwide. Microorganisms play critical roles promoting ecosystem nutrient transformations material circulations. However, the long-term effects this farming system on soil health microbial community stability, addition to their relationships with rice yields, remain...

10.1016/j.geoderma.2022.115745 article EN cc-by-nc-nd Geoderma 2022-02-10

The environmental impacts of genetically modified (GM) plants remain a controversial global issue. To address these issues, comprehensive risk assessments GM is critical for the sustainable development and application transgenic technology. In this paper, significant differences were not observed between microbial metagenomic metabolomic profiles in surface waters Bt rice (T1C-1, line) non-Bt cultivars (Minghui 63 (the isogenic Zhonghua 11 conventional japonica cultivar)). contrast, apparent...

10.1038/s43705-023-00217-9 article EN cc-by ISME Communications 2023-01-23

Acyl-CoA:cholesterol acyltransferase (ACAT) plays important roles in cellular cholesterol homeostasis and is involved atherosclerosis. ACAT-1 protein located mainly the ER. The hydropathy plot suggests that contains multiple transmembrane segments. We inserted either hemagglutinin tag or HisT7 at various hydrophilic regions within human used immunofluorescence microscopy to determine topography of tagged proteins expressed mutant Chinese hamster ovary cells lacking endogenous ACAT. All are...

10.1074/jbc.274.33.23276 article EN cc-by Journal of Biological Chemistry 1999-08-01

Milk in mammals is a key source of lipids for offspring, providing both critical energy and essential fatty acids. For lactating sows, palmitic acid one the most abundant acids milk, 10~12% suckling pig total dietary supply. However, effects exogenous on milk fat synthesis sow mammary glands are not well-known. In this study, we investigated lipogenic genes porcine epithelial cells (pMECs) to explore role mediating triacylglycerols (TAG) synthesis.Porcine were cultured 24 h presence...

10.1186/s12263-018-0606-6 article EN cc-by Genes & Nutrition 2018-07-06

Rapeseed (Brassica napus L.) is one of the most important oil crops almost all over world. Seed-related traits, including content (OC), silique length (SL), seeds per (SS), and seed weight (SW), are primary targets for yield improvement. To dissect genetic basis these 192 recombinant inbred lines (RILs) were derived from two parents with distinct length. High-density linkage map a total 1610.4 cM constructed using 1,329 double-digestion restriction site associated DNA (ddRAD) markers, 107...

10.1270/jsbbs.16116 article EN Breeding Science 2017-01-01

Streptomyces virginiae phenylpyruvate decarboxylase (PPDC) has not been identified before. Two putative branched-chain α-keto acid dehydrogenase subunit genes bkdC and bkdD from S. are similar to halves of other PPDC coding sequences. We cloned characterized them biochemically in this work. The two proteins formed a stable complex attested by pull-down assay, consistent with the finding that their soluble expression was obtained only when they were coexpressed Escherichia coli. subunits...

10.1021/acschembio.7b00307 article EN ACS Chemical Biology 2017-07-18

To study the dilatation characteristics of ATP-sensitive potassium channel (KATP) SUR2B/Kir6.1 subtype opener iptakalim (Ipt) in pulmonary arterioles, and to explore its possible mechanism.Vessels pressure-diameter monitoring perfusion technique was used observe effects Ipt rats fourth arterioles (n=6~8). After were pre-treated with removing endothelium or pre-incubated KATP blocker glibenclamide (Gli), cyclo-oxygenase (COX) inhibitor indomethacin (Indo) nitric oxide synthase (NOS)...

10.13459/j.cnki.cjap.2016.03.013 article EN PubMed 2016-03-08

In rapeseed ( Brassica napus L.), lipid transfer protein (LTP) and seed storage albumin (SSA) gene families are involved in metabolism. Understanding the mechanism of oil biosynthesis has great value to increase production. The LTPs SSA were identified Brassicaceae. divided into six groups according their sequences, all five species Brassicaceae also had same pattern. genes at a higher expression level evenly distributed across except group ii. these two showed different patterns, with most...

10.1139/cjb-2021-0176 article EN Botany 2022-03-30

Abstract The family Orchidaceae, including many medicinal plants, is a famous ornamental plant. While, Dendrobium huoshanense an endangered Orchidaceae species mainly distributed in Huoshan county, Anhui province, China. Here, using the program MITObim v1.7, we assembled complete chloroplast genome sequence of D. , which consists 153,188 bp, and pair inverted repeats (IR) 26,525 bp. also includes one small large single-copy region (SSC LSC) 14,524 bp 85,614 respectively. GC content 40.0%, it...

10.21203/rs.3.rs-1527666/v1 preprint EN cc-by Research Square (Research Square) 2022-04-11

Abstract In this study, the transcriptional regulation of PI3KC3 by three transcript factors (PPARγ, PPARα and STAT3) potential role in mediating lipid accumulation were determined yellow catfish Pelteobagrus fulvidraco . The 5’-deletion assay, overexpression site-mutation assay electrophoretic mobility shift suggested that PPARα, PPARγ STAT3 negatively regulated promoter activity pi3kc3 Moreover, inactivation was directly mediated under fatty acid (FA) treatment. Using primary hepatocytes...

10.21203/rs.3.rs-1166833/v1 preprint EN cc-by Research Square (Research Square) 2021-12-28
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