A5103120010- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Blood transfusion and management
- Adrenal and Paraganglionic Tumors
- Anesthesia and Sedative Agents
- Pituitary Gland Disorders and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Anesthesia and Pain Management
- Thermal Regulation in Medicine
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Hormonal Regulation and Hypertension
- Anesthesia and Neurotoxicity Research
- Nausea and vomiting management
- Pain Mechanisms and Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cancer survivorship and care
- Enhanced Recovery After Surgery
- Thermoregulation and physiological responses
- Neurogenetic and Muscular Disorders Research
- Drug-Induced Adverse Reactions
- Music Therapy and Health
- Airway Management and Intubation Techniques
- Surgical site infection prevention
- Pain Management and Treatment
Peking Union Medical College Hospital
2016-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
Academy of Medical Sciences
2019-2023
Academia Sinica
2019-2022
Shanghai Sixth People's Hospital
2021
Shanghai Jiao Tong University
2021
United States Government Accountability Office
2014
Development Fund
2014
BACKGROUND: Patients with lung cancer often experience reduced functional capacity and quality of life after surgery. The current study investigated the impact a short-term, home-based, multimodal prehabilitation program on perioperative in patients undergoing video-assisted thoracoscopic surgery (VATS) lobectomy for nonsmall cell (NSCLC). METHODS: A randomized controlled trial was conducted 73 patients. group (n = 37) received 2-week intervention before surgery, including aerobic resistance...
Inadvertent intraoperative hypothermia (core temperature <36°C) is a frequently preventable complication with several adverse consequences. Our study aimed to determine the overall incidence of inadvertent and its risk factors associated clinical outcomes in this national survey China.We conducted cross-sectional 30 days postoperative follow-up from November 2014 through August 2015. A total 3132 eligible patients underwent general anesthesia were randomly selected 28 hospitals nationwide...
Introduction Pheochromocytoma/paraganglioma (PPGL) resection remains a high-risk surgical procedure owing to severe haemodynamic instability, which can lead myocardial injury after non-cardiac surgery (MINS). MINS is the most common and easily overlooked cardiovascular complication results in increased postoperative mortality prolonged inpatient hospitalisation. We aimed develop validate predictive model for patients undergoing laparoscopic PPGL resection. Methods analysis The PPGL-MINS...
Inadvertent intraoperative hypothermia (core temperature < 36 °C) is a common but preventable adverse event. This study aimed to determine whether active warming reduced bleeding in patients undergoing major operations: open thoracic surgery and hip replacement surgery. The was pilot, prospective, parallel two-arm randomized controlled trial. Eligible were randomly allocated two groups: passive (PW), with application of cotton blanket (thermal insulation), or (AW), forced-air system. primary...
Inadvertent intraoperative hypothermia (core temperature <36 °C) is a frequent but preventable complication of general anesthesia. Accurate risk assessment individual patients may help physicians identify at for and apply preventive approaches, which include active warming. This study aimed to develop validate risk-prediction model hypothermia. Two independent observational studies in China, the Beijing Regional Survey China National Survey, were conducted 2013 2014, respectively, determine...
HR7056 is a new benzodiazepine, showing more faster acting onset and recovery than currently available short-acting sedatives. To avoid inadequate anesthesia predict return of cognition, allowing for immediate neurological evaluation, pharmacokinetics pharmacodynamics were characterized in Chinese healthy subjects. We report on modeling the data simulations dosage regimens future study. Up to 63 subjects evaluated, using Bispectral Index (BIS) Modified Observer’s Assessment...
Ever-increasing noncardiac surgeries are performed in patients aged 80 years or over with coronary artery disease (CAD). The objective of the study was to explore incidence and risk factors perioperative cardiac complications (PCCs) for oldest-old CAD undergoing surgery, which have not been evaluated previously.A total 547 patients, years, a history who underwent surgery were enrolled this retrospective study. Perioperative clinical variables extracted from electronic medical records...
Abstract Background Preoperative anxiety is associated with increased use of anesthetics and poorer postoperative outcomes. However, the prevalence preoperative has not been characterized in Chinese patients. In this study, we aimed to estimate overall adult patients explore sociodemographic clinical factors China. Methods This study was a multicenter cross‐sectional conducted at 32 tertiary referral centers China from September 1 October 31, 2020. Adult scheduled for elective surgery were...
Objectives. There have been no fully validated tools for the rapid identification of surgical patients at risk intraoperative hypothermia. The objective this study was to validate performance a previously established prediction model in estimating hypothermia prospective cohort. Methods. In observational study, consecutive adults scheduled elective surgery under general anesthesia were enrolled prospectively tertiary hospital between September 4, 2020, and December 28, 2020. An score...
Background and Objectives The safety of laparoscopic resection very large pheochromocytomas is unclear, preoperative preparation may benefit from refinement. This retrospective study was designed to determine the correlation between tumor size perioperative characteristics by evaluating data patients who underwent pheochromocytomas. Methods A total 253 were grouped according their diameter: diameter ≥8 cm, Glarge (G lg ) ( n = 30); 6 8 Gmedium md 57); <6 Gsmall sm 166). compared among...
Prehabilitation has been shown to have a positive effect on the postoperative recovery of functional capacity in patients undergoing video-assisted thoracoscopic surgery (VATS) lobectomy. The optimal way implement prehabilitation programs, such as forms prehabilitation, duration, intensity, and methods improve compliance, remained be studied. This for Thoracic Surgery Study will compare effectiveness multimodal aerobic training-only programs lobectomy.This randomized pragmatic trial...
BACKGROUND: It remains unclear whether the benefits of performing perioperative allogeneic red blood cell (RBC) transfusion outweigh risks postoperative wound infection. The aim this study was to assess impact RBC as well dose–response relationship on infections in surgical patients a large cohort. METHODS: As retrospective observational study, national Hospital Quality Monitoring System database used retrieve information about in-hospital without limitations types People’s Republic China...
Fluid management during major gynecologic oncology surgeries faces great challenges due to the distinctive characteristics of patients with malignancies as well features surgical procedure. Intraoperative goal-directed fluid therapy (GDFT) has been proven be effective in reducing postoperative complications among colorectal surgeries; however, efficacy GDFT not fully studied malignancy surgeries. This study aimed discuss influence practice undergoing surgery.This was a controlled...
This study sought to evaluate the diagnostic accuracy of peri-operative diaphragm ultrasound in assessing post-operative residual curarization (PORC).Patients undergoing non-thoracic and non-abdominal surgery under general anaesthesia were enrolled from July 2019 October at Peking Union Medical College Hospital. A train-of-four ratio (TOFr) lower than 0.9 was considered as gold standard for PORC. Diaphragm parameters included diaphragmatic excursion (DE) thickening fraction (DTF) during...
Multimodal analgesia (MMA) is a critical component of enhanced recovery after surgery (ERAS). However, little research revealed its intraoperative implementation by anesthesiologists, who are on the front line defending against surgical pain. Therefore, objective our study to assess adherence anesthesiologists MMA comprehensively. A retrospective was conducted involving patients undergoing lung resection, knee arthroplasty, and radical mastectomy from pre/post-implementation year (Jan 1,...
Abstract Background Perioperative acute kidney injury (AKI) has been one of the leading causes morbidity and mortality for surgical patients. Pheochromocytoma is a rare, catecholamine-secreting neuroendocrine neoplasm characterized by typical long-term hypertension that needs resection. Our objective was to determine whether intraoperative mean arterial pressures (MAPs) less than 65 mmHg are associated with postoperative AKI after elective adrenalectomy in patients pheochromocytoma. Methods...
BACKGROUND: The aim of this study was to explore the associations preoperative sarcopenia (muscle mass depletion) and myosteatosis quality attenuation) with incidence postinduction hypotension (PIH) postoperative complications among patients undergoing major gynecologic surgery. METHODS: Based on a previous prospective surgical registry patients, we included an available abdominal computed tomography (CT) scan performed within 3 months before cross-sectional muscle density at third lumbar...
Background Anaphylactic reactions during anesthesia and operation are common life threatening. Follow-up investigation is necessary for avoiding potential re-exposure of the patients to offending drugs. The purpose this study was assess cellular allergen stimulation test (CAST) as a diagnostic instrument in immunoglobulin E (IgE)- non-IgE-mediated anaphylactic reactions. Methods This included 25 who developed perioperative 10 subjects that tolerated anesthetics other drugs period from...