Hui Wen

ORCID: 0000-0002-8719-1238
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About
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Research Areas
  • Schizophrenia research and treatment
  • Electroconvulsive Therapy Studies
  • Paranormal Experiences and Beliefs
  • Mental Health Treatment and Access
  • Tryptophan and brain disorders
  • Fibroblast Growth Factor Research
  • Mental Health Research Topics
  • Growth Hormone and Insulin-like Growth Factors
  • Bipolar Disorder and Treatment
  • Apelin-related biomedical research
  • Transcranial Magnetic Stimulation Studies
  • Spaceflight effects on biology
  • Circadian rhythm and melatonin
  • Bariatric Surgery and Outcomes
  • Renal and related cancers
  • Adrenal Hormones and Disorders
  • Cancer, Stress, Anesthesia, and Immune Response
  • Pelvic floor disorders treatments
  • Family Caregiving in Mental Illness
  • Pharmacovigilance and Adverse Drug Reactions
  • Parkinson's Disease Mechanisms and Treatments
  • Stroke Rehabilitation and Recovery
  • Epigenetics and DNA Methylation
  • Neural and Behavioral Psychology Studies
  • Cardiac electrophysiology and arrhythmias

Songjiang District Central Hospital
2024-2025

Shanghai Jiao Tong University
2006-2024

Shanghai Mental Health Center
2014-2024

Southwest University
2023

Sichuan University
2023

West China Hospital of Sichuan University
2023

Mianyang Third People's Hospital
2019

Kidney stones, a common urological disease, may involve the brain-kidney axis in their formation, though specific mechanism remains unclear. This study aimed to investigate effects of blue light on relevant metabolic indicators and oxidative stress status rats with kidney stones through axis. A rat model was established by administering 1% ethylene glycol 2% ammonium chloride. Subsequently, intervention applied, outcomes were compared those control group normal rats. Our findings revealed...

10.1038/s41598-025-85586-y article EN cc-by-nc-nd Scientific Reports 2025-01-30

<title>Abstract</title> <bold>Purpose</bold>: This study aims to analyze the preferences of patients with 20-25 mm kidney stones in Songjiang District, Shanghai, for two treatment options: flexible ureteroscopy lithotripsy (FURL) and percutaneous nephrolithotomy (PNL), as well factors influencing these preferences. Additionally, it seeks compare outcomes surgical methods. <bold>Methods</bold>: A retrospective analysis was conducted on 173 who underwent intervention (ranging from 20 25...

10.21203/rs.3.rs-6237736/v1 preprint EN 2025-04-03

Importance Bipolar mania is a common disabling illness. Electroconvulsive therapy (ECT) an effective treatment for patients with severe mania, though it limited by the risk of cognitive adverse effects. Magnetic seizure (MST) as alternative to ECT bipolar has not yet been reported. Objective To compare effectiveness and effects MST in mania. Design, Setting, Participants This randomized clinical trial was conducted at Shanghai Mental Health Center from July 1, 2017, through April 26, 2021....

10.1001/jamanetworkopen.2024.7919 article EN cc-by-nc-nd JAMA Network Open 2024-04-29

Abstract Aims Patients with severe mental disorders in low-resource settings have limited access to services, resulting overwhelming caregiving burden for families. In extreme cases, this has led the long-term restraining of patients their homes. China underwent a nationwide initiative unlock and provide continued treatment. This study aims quantify household economic families after unlocking treatment, identify factors associated increased due schizophrenia. Methods A total 264 subjects...

10.1017/s2045796019000775 article EN cc-by Epidemiology and Psychiatric Sciences 2019-12-16

Psychosocial stressors may worsen psychotic symptoms in schizophrenia, while social support could protect against the effects of stress schizophrenia. Hypothalamus-pituitary-adrenal axis dysfunction has been associated with Hair cortisol concentrations (HCC) allow assessment cumulative secretion over preceding 3 months. The relationship between HCC, psychosocial stressors, support, and clinical characteristics schizophrenia needs to be explored. One hundred nine patients 86 healthy controls...

10.3389/fpsyt.2020.572656 article EN cc-by Frontiers in Psychiatry 2020-09-24

Impaired social functions contribute to the burden of schizophrenia patients and their families, but predictive tools functioning prognosis specific factors are undefined in Chinese clinical practice. This article explores a machine learning tool identify whether will achieve significant functional improvement after 3 months atypical antipsychotic monopharmacy finds defined risk using multicenter study.A study on (AAP) treatment with (SALT-C) was conducted from July 2011 August 2018. Data...

10.2147/ndt.s280757 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2021-03-01

Background Repetitive transcranial magnetic stimulation (rTMS) is now an established, safe, and effective treatment for adults with depression. However, specific research in rTMS use elderly patients acute depression scarce. Objective The aim of the present study was to investigate efficacy add-on a clinical sample older experiencing phase Method This examined 114 (54 [aged ≥60] 60 18–59]) who were drug free at baseline. They treated least 10 sessions 4 weeks along 1 antidepressant. Symptoms...

10.1097/yct.0000000000000648 article EN Journal of Ect 2020-01-16

We report on a case of female patient who had serious side effects from treatment with clozapine and chlorpromazine the appeared to have withdrawal reaction cessation clozapine. During process she was misdiagnosed as having malignant syndrome. This highlights importance clinicians being able distinguish syndrome reactions, be familiar prevention methods for both.我们报告一名女性患者在抗精神病药物过程中 使用氯氮平和氯丙嗪出现严重的不良反应,随后患者 氯氮平的突然停药后出现撤药反应。在处理过程中曾 误诊为恶性综合征,因此临床医生需要识别恶性综合 征及撤药反应,熟悉处理及预防方法。.

10.11919/j.issn.1002-0829.216048 article EN PubMed 2016-08-25

Abstract Background Previous observational studies have found an association between vitamin D and stress urinary incontinence(SUI), but it remains controversial the causal relationship is unknown. In present study, we investigated incontinence through a Mendelian randomization study. Methods Summary statistics for 25(OH)D SUI were obtained from genome-wide (GWAS). To explore potential them, MR analysis was applied. The effects mainly estimated using standard inverse variance weighting (IVW)...

10.21203/rs.3.rs-3857165/v1 preprint EN cc-by Research Square (Research Square) 2024-01-22

<title>Abstract</title> <bold>Objective</bold> The study aimed to investigate the protective effects of resveratrol against NSAIDs drug-related intestinal injury in rats by regulating expression Ang II, as well mitigating oxidative stress and inflammatory reactions mucosa. <bold>Method</bold> 60 male Sprague-Dawley were randomly assigned five groups. control group received a daily gavage saline (1 ml/100 g/d) standard plain-air environment. rest housed hypoxic chamber, aspirin at dosage 200...

10.21203/rs.3.rs-4607078/v1 preprint EN Research Square (Research Square) 2024-07-15

<title>Abstract</title> Kidney stones, a common disease in urology, are formed by multiple factors, among which the brain-kidney axis may play an important role occurrence and development of kidney although specific mechanism remains to be elucidated. This study aims investigate effects blue light on relevant metabolic indicators oxidative stress status rats with stones through axis. To this end, we established rat model intervened light, comparing it normal rats. We found that compared...

10.21203/rs.3.rs-4972575/v1 preprint EN Research Square (Research Square) 2024-10-04

Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare and aggressive tumor characterized by pathogenic alterations in the fumarate hydratase ( FH) gene. Clear (clear common (RCC) associated with von Hippel-Lindau VHL) gene variations. Here, we reported case of bilateral RCCs. A 60-year-old man was admitted to hospital 3.6 cm × 3.3 mass right kidney 2.8 2.3 nodule left kidney. Pathologically, showed nested growth pattern cells clear cytoplasm FH positive...

10.1177/10668969231195072 article EN International Journal of Surgical Pathology 2023-09-16

10.1016/s1006-7191(06)60027-6 article EN Acta Metallurgica Sinica (English Letters) 2006-04-01

Multiple neurotrophic factors, including vascular endothelial growth factor (VEGF), fibroblast (FGF)-2, nerve (NGF) and insulin-like factor(IGF)-1, have been shown to play important roles in the pathophysiology of mood disorders. However, insufficient clinical data supporting importance these factors disorders, especially manic episode, made inconclusive make a connection between disorder. This study intended investigate possible peripheral biomarkers serum episode bipolar We aimed whether...

10.1016/s0924-9338(14)77996-9 article EN European Psychiatry 2014-01-01
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