A5112839045- Cardiac Arrest and Resuscitation
- Coronary Interventions and Diagnostics
- Disaster Response and Management
- Trauma and Emergency Care Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Paraquat toxicity studies and treatments
- Emergency and Acute Care Studies
- Acute Kidney Injury Research
- Adipokines, Inflammation, and Metabolic Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Health and Disease Prevention
- Lipoproteins and Cardiovascular Health
- Heme Oxygenase-1 and Carbon Monoxide
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Gout, Hyperuricemia, Uric Acid
- Nitric Oxide and Endothelin Effects
- Cardiac Ischemia and Reperfusion
- Influenza Virus Research Studies
- Animal Disease Management and Epidemiology
- Aortic Disease and Treatment Approaches
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Cardiac Structural Anomalies and Repair
- Ultrasound in Clinical Applications
Nanyang Normal University
2025
Third Xiangya Hospital
2010-2025
Central South University
2012-2025
Sun Yat-sen Memorial Hospital
2025
Sun Yat-sen University
2025
Sichuan University
2015-2024
West China Hospital of Sichuan University
2015-2024
Tianjin Medical University
2024
Second Hospital of Tianjin Medical University
2024
Shanghai Normal University
2024
The treatment of in-stent restenosis (ISR) after drug-eluting stent (DES) implantation remains challenging in current clinical practice.
Pulmonary fibrosis is one of the most common complications paraquat (PQ) poisoning, which demands for more effective therapies. Accumulating evidence suggests adiponectin (APN) may be a promising therapy against fibrotic diseases. In current study, we determine whether exogenous globular APN isoform protects pulmonary in PQ-treated mice and human lung fibroblasts, dissect responsible underlying mechanisms. BALB/C were divided into control group, PQ + low-dose high-dose group. Mice sacrificed...
Abstract Closure of live poultry markets was implemented in areas affected by the influenza virus A(H7N9) outbreak China during winter, 2013–14. Our analysis showed that closing most cities Guangdong and Zhejiang provinces highly effective reducing risk for H7N9 infection humans.
Summary Background and objective To observe the outcomes of AKI following multiple wasp stings. Design, setting, participants, & measurements Eighty-one patients (mean age ± SD, 45.5±14.7 years; 55 men 26 women; mean Acute Physiology Chronic Health Evaluation II score, 16.85±2.78) with stings between 1997 2011 were retrospectively analyzed. Data on their demographic characteristics, initial modalities renal replacement therapy (RRT), urine output, serum creatinine, bilirubin, myoglobin,...
Objective Endolymphatic hydrops is the primary pathological feature of Menière’s disease (MD). An imbalance between endolymphatic fluid production and absorption due to sac (ES) dysfunction may be major cause hydrops. This study aimed identify characterize global protein expression ES in MD patients using microscale proteomics for first time. Methods Liquid chromatography–tandem mass spectrometry was used analyze samples from six acoustic neuroma (AN) (as control) differentially expressed...
Background: Previous studies indicated discrete lifestyle health metrics that benefit cardiovascular are associated with better prognosis in inflammatory bowel disease (IBD), while evidence regarding the comprehensive impact of remains limited. This study aimed to investigate association between overall indicator, Life’s Essential 8 (LE8), and adverse outcomes IBD. Materials methods: We included 3,232 IBD participants recruited from UK Biobank 2006 2010. LE8 encompasses metrics, including...
A novel avian influenza virus, A(H7N9), emerged in China early 2013 and caused severe disease humans, with infections occurring most frequently after recent exposure to live poultry. The distribution of A(H7N9) incubation periods is interest epidemiologists public health officials, but estimation the complicated by interval censoring exposures. Imputation midpoint intervals was used some studies, resulting estimated mean times approximately 5 days. In this study, we period human using data...
Toll-like receptor 4 (TLR4) expression is increased in activated monocytes, which play a critical role the pathogenesis of coronary artery disease (CAD). However, mechanism remains unclear. Regulatory factor X1 (RFX1) transcription regulating epigenetic modifications. In this study, we investigated whether RFX1 and modifications mediated by contributed to overexpression TLR4 monocytes. Compared with those controls, mRNA protein were downregulated was upregulated CD14+ monocytes obtained from...
Because of the rapid development and extensive use nuclear technology, ionizing radiation has become a large threat to human health. Until now, there been no practicable radioprotector for routine clinical application because severe side effects, high toxicity, short elimination half-life. Herein, we develop highly efficient radioprotection strategy using selenium-containing polymeric drug with low toxicity long circulation by removing reactive oxygen species (ROSs). The is prepared...
Objectives To investigate the effect of point‐of‐care ultrasound (POCUS) use by emergency physician (EPs) on diagnosis, treatment, and safety POCUS in patients with aortic dissection (AD) settings. Methods Patients presenting to department West China Hospital Sichuan University suspected AD from July 1, 2016, December 31, 2016 were divided into a control group an (US) group. The was evaluated routine procedures for triage, treatment. In addition, EP examination performed US furtherly...
Cancer stem cells (CSCs) in gastric cancer (GC) have been established recently as key therapeutic targets for the successful treatment of GC. Emerging evidence suggests that both CSCs and should be eradicated to achieve optimal efficacy. In present study, salinomycin, which has reported kill CSCs, was used combination with docetaxel, a chemotherapeutic drug is first-line therapy GC, eradicate GC (SCs) cells. Salinomycin docetaxel were loaded separately into poly(D,L-lactic-co-glycolic...
Endothelial dysfunction participates in the development and progression of salt-sensitive hypertension. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor nitric oxide synthase (NOS). The objectives this study were to investigate impact a high salt diet on PRMT/ADMA/DDAH (protein arginine methyltransferases; dimethylaminohydrolase) pathway Dahl (DS) rats SS-13BN consomic (DR) rats, explore mechanisms that regulate ADMA metabolism independent blood pressure reduction. Plasma levels...
The specific mechanisms underlying paraquat (PQ)-induced lung injury remain unknown, which limits understanding of its cytotoxic potential. Although oxidative stress has been established as an important mechanism PQ toxicity, multiple antioxidants have proven ineffective in attenuating the deleterious effects PQ. Adiponectin, shows anti-oxidative and antinitrative effects, may potential to reduce PQ-mediated injury. present study determined protective action globular domain adiponectin (gAd)...