A5115602279- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Vaccine Coverage and Hesitancy
- Thermography and Photoacoustic Techniques
- Influenza Virus Research Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Liver Disease and Transplantation
- Virology and Viral Diseases
- Acute Kidney Injury Research
- Neurological and metabolic disorders
- Muscle and Compartmental Disorders
- Dialysis and Renal Disease Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Lipoproteins and Cardiovascular Health
- Genetic factors in colorectal cancer
- Virtual Reality Applications and Impacts
- Reproductive System and Pregnancy
- Solid State Laser Technologies
- Cervical Cancer and HPV Research
- Viral Infections and Outbreaks Research
- Rabies epidemiology and control
- Vascular Malformations Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
National Yang Ming Chiao Tung University
2007-2025
Taipei Veterans General Hospital
2011-2025
Shijiazhuang Yiling Pharmaceutical (China)
2024
Hangzhou First People's Hospital
2024
Westlake University
2024
Hangzhou Center for Disease Control and Prevention
2023-2024
Nanjing University of Chinese Medicine
2022-2024
Beijing Tian Tan Hospital
2023-2024
Capital Medical University
2023-2024
National Clinical Research Center for Digestive Diseases
2023-2024
Qimai Feiluoping decoction (QM), a Traditional Chinese Medicine formula, has been included in rehabilitation program for functional disorders of discharged COVID-19 patients. QM proved to effectively improve the clinical symptoms and imaging signs PF convalescent patients.This study explore pharmacological effect against from perspectives imaging, pathological staining, molecular mechanisms, identify possible active components.Micro-CT immunohistochemical staining were investigated verify...
Background: Pulmonary function tests offer crucial parameters for evaluating lung health and predicting clinical outcomes. Hyperlipidemia, a prevalent metabolic disorder, has been linked to declining pulmonary function. Statins are an essential therapy lowering lipid levels in hyperlipidemia. Objectives: This study aims investigate the therapeutic potential of statins mitigating decline Design: is retrospective cohort study. Methods: Out 8286 patients who underwent spirometry testing from...
Summary Background and objective To observe the outcomes of AKI following multiple wasp stings. Design, setting, participants, & measurements Eighty-one patients (mean age ± SD, 45.5±14.7 years; 55 men 26 women; mean Acute Physiology Chronic Health Evaluation II score, 16.85±2.78) with stings between 1997 2011 were retrospectively analyzed. Data on their demographic characteristics, initial modalities renal replacement therapy (RRT), urine output, serum creatinine, bilirubin, myoglobin,...
The seasonal influenza vaccine coverage remains suboptimal among children even though guardians expressed high willingness to vaccinate their children. This study aimed determine the association between hesitancy and uptake facilitate vaccination; thus, bridging gap. A cross-sectional design, using stratified cluster random sampling, was conducted of 0–59-month-old Chinese from July October in 2019. structural equation model applied explore interrelationships factors including hesitancy,...
10-year atherosclerotic cardiovascular disease (ASCVD) risk scores were useful for predicting large vessel disease, but the relationships between them and cerebral small (CSVD) unclear. Our study aimed to evaluate associations of ASCVD with CSVD its magnetic resonance imaging (MRI) markers.
Seasonal influenza vaccine coverage remains low in China due to possible hesitancy (IVH) and practical issues. We sought investigate IVH its determinants among children's guardians the elderly for a better understanding of situation future intervention.We performed two cross-sectional studies identify profiles using stratified cluster random sampling an eastern province 2019.Of 1564 522 elders, 43.2% (95%CI: 40.4-46.0%) 33.5% elders 29.5-37.6%) had IVH. 'From rural area' (odds ratio: 1.36),...
The expression of tetraspanin CD9 was found on blastocysts in mice and endometrium epithelial cells human bovine. However, it remains unknown how is involved the precise dialogue between embryo uterus during early pregnancy. This study designed to investigate functional roles implantation with monoclonal antibody against protein (anti-CD9 mAb) antisense oligonucleotide gene (AS-CD9). Our results showed that intrauterine injection anti-CD9 mAb day 4 pregnancy significantly increased number...
Loxoprofen (LOXO) is a non-steroidal anti-inflammatory drug. Repeated oral administrations induce gastrointestinal side effects. Patches are promising alternative.The aim of this study was to investigate the effects organic amines on skin permeation LOXO and finally design patch with comparable profile pharmacodynamic commercial LOXONA® plaster.The were assessed by flux values from isopropyl myristate (IPM), using horizontal diffusion cell rabbit skin. FTIR spectroscopy used confirm ion-pair...
Avian paramyxovirus serotype 4 (APMV-4) is found sporadically in wild birds worldwide, and it an economically important poultry pathogen. Despite the existence of several published strains, very little known about distribution, host species, transmission APMV-4 strains. To better understand relationships among these factors, we conducted surveillance domestic six provinces China suspected being intercontinental flyways sites interspecies transmission. was 9,160 representing seven 1,461 live...
Acute kidney injury (AKI) caused by bee stings is common, with characteristics of acute onset, severe illness, and high mortality. Melittin, a major component venom, has been considered to play key role in sting related AKI. This study aims illustrate whether melittin could lead apoptosis renal tubular epithelial cells (RTECs) investigate its mechanism.In vivo, 45 mice were randomly divided into the group (n=30, injected tail vein according total dose 4.0 ug/g weight) control (n=15, same...
Pipeline transportation plays a key role in energy security and economic development, the accurate localization of leak points significantly reduces environmental pollution losses. This article proposes pipeline method based on ensemble empirical modal decomposition algorithm with Hilbert spectrum analysis (EEMD-HT) leakage-grading resolution strategy. The classifies leakage level by adaptive pressure threshold uses acoustic signal as basis for localization. At same time, strategy is...
Previous studies have reported that senolytic drugs can reverse obesity-mediated accumulation of senescent cells in the ovary and protect against cisplatin-induced ovarian injury by removing cells. Early intervention with ABT-263 has been shown to mitigate aging. However, it remains unknown whether treatment could rejuvenate aged reproductively old females. Therefore, current study was aimed investigate advanced age ameliorate age-related decline function. Fourteen 16-month-old mice a...
Pulmonary fibrosis (PF) is one of the pathologic changes in COVID-19 patients convalescence, and it also a potential long-term sequela severe patients. Qimai Feiluoping decoction (QM) traditional Chinese medicine formula recommended national medical program for convalescent patients, PF its indications. Through clinical observation, QM was found to improve symptoms pulmonary function reduce degree To further explore pharmacological mechanisms possible active components anti-PF effect,...
Background: Cirrhosis-related acute-on-chronic liver failure (ACLF) is associated with high morbidity and mortality rates. Prognostic models of ACLF have been developed; however, few studies focused on the occurrence ACLF. This study aimed to identify factors that predict development ACLF, hepatic encephalopathy (HE), infection in patients cirrhosis. Methods: Patients cirrhosis were enrolled, serum levels calcitriol, Cluster Differentiation 26 (CD206), macrophage-inducible lectin receptor...
We demonstrate high-power 355 nm ultraviolet (UV) picosecond (ps) laser using a type I phase-matching nonlinear optical crystal of La(2)CaB(10)O(19) (LCB), which possesses the characteristic non-hygroscopicity. The third harmonic generation was successfully achieved from two types 1064 ps fundamental lasers. maximum output power 7.81 W UV obtained with pump 35.2 (80 MHz repetition rate, 10 pulse width) conversion efficiency 22.2%. experimental results show that LCB is promising candidate for...
We prepared octreotide (OCT)-modified curcumin plus docetaxel micelles to enhance active targeting and inhibit tumor metastasis by destroying vasculogenic mimicry (VM) channels. Soluplus was applied as an amphiphilic material form via film dispersion. The cytotoxic effects, cellular targeting, inhibitory effects on were systematically evaluated in vitro using A549 cells, vivo antitumor xenograft tumor-bearing mice. In assays indicated that the OCT-modified showed robust cytotoxicity cells...
Abstract This study aimed to examine hTERC gene in different grades of cervical intraepithelial neoplasia (CIN) and cancer, the association between high risk-human papillomavirus (HR-HPV) infection. Patients who underwent cancer screening at Second Affiliated Hospital Kunming Medical University October 2010 December 2011 were enrolled. All patients liquid-based cytology test hybrid capture 2 (HC2) for HPV detection. was examined using fluorescence situ hybridization (FISH). Cervical...
Residents play an important role as teachers of junior colleagues and medical students. Clinical teaching also helps residents in clinical learning. However, the skills required for to be competent are rarely described systemically. Beyond widely adopted six core competencies postgraduate training by Accreditation Council Graduate Medical Education (ACGME), should further developed, milestones clearly defined serve better references resident programs. Twenty members, including five experts...