A5068165513- SARS-CoV-2 and COVID-19 Research
- Mosquito-borne diseases and control
- SARS-CoV-2 detection and testing
- Invertebrate Immune Response Mechanisms
- Insect symbiosis and bacterial influences
- Viral Infections and Outbreaks Research
- Marine animal studies overview
- Viral gastroenteritis research and epidemiology
- Genomics and Phylogenetic Studies
- Marine Biology and Ecology Research
- COVID-19 epidemiological studies
- Microbial Community Ecology and Physiology
- Marine and coastal plant biology
- Malaria Research and Control
- Physiological and biochemical adaptations
- Vector-Borne Animal Diseases
- Genetic diversity and population structure
- Insect Resistance and Genetics
- Plant and animal studies
- Amphibian and Reptile Biology
- Evolution and Paleontology Studies
- Coral and Marine Ecosystems Studies
- Respiratory viral infections research
- Fossil Insects in Amber
- Methane Hydrates and Related Phenomena
Universidade Estadual de Campinas (UNICAMP)
2019-2024
Queen Mary University of London
2024
Global Development Network
2024
Fundação Oswaldo Cruz
2021-2023
Universidade Federal do Rio de Janeiro
1991-2020
Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular
2020
Instituto Butantan
2018
GISAID is a global data science initiative and the primary source of genomic associated metadata all influenza viruses, Respiratory Syncytial Virus (RSV) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pandemic causing disease 2019 (COVID-19).GISAID's publicly accessible sharing platform enables collaboration over 42,000 participating researchers from 198 nations generators 3,500 institutions across globe.Since first wholegenome sequences were made available by China CDC...
We propose a novel, non-discriminatory classification of monkeypox virus diversity. Together with the World Health Organization, we named three clades (I, IIa and IIb) in order detection. Within IIb, cause current global outbreak, identified multiple lineages (A.1, A.2, A.1.1 B.1) to support real-time genomic surveillance.
Abstract Genomic sequencing is essential to track the evolution and spread of SARS-CoV-2, optimize molecular tests, treatments, vaccines, guide public health responses. To investigate global SARS-CoV-2 genomic surveillance, we used sequences shared via GISAID estimate impact intensity turnaround times on variant detection in 189 countries. In first two years pandemic, 78% high-income countries sequenced >0.5% their COVID-19 cases, while 42% low- middle-income reached that mark. Around 25%...
Abstract The emergence of SARS-CoV-2 variants concern has prompted the need for near real-time genomic surveillance to inform public health interventions. In response this need, global scientific community, through unprecedented effort, sequenced and shared over 10 million genomes GISAID, as May 2022. This extraordinarily high sampling rate provides a unique opportunity track evolution virus in real-time. Here, we present outbreak.info , platform that currently tracks 40 combinations PANGO...
The timely release of SARS-CoV-2 first genomic sequences allowed the identification etiologic agent and development diagnostic protocols. Genomic sequencing was a crucial step in generating data for driving laboratory response detections since start COVID-19 pandemic. Because all progression achievements that genetic sequence represents public health response, Pan American Health Organization (PAHO) collaboration with countries’ laboratories, started implementation network strengthening...
Cetaceans are a group of aquatic mammals with the largest body sizes among living animals, including giant representatives such as blue and fin whales. To understand genetic bases gigantism in cetaceans, we performed molecular evolutionary analyses on five genes (GHSR, IGF2, IGFBP2, IGFBP7, EGF) from growth hormone/insulin-like factor axis, four (ZFAT, EGF, LCORL, PLAG1) previously described related to size species evolutionarily close pigs, cows, sheep. Our dataset comprised 19 seven which...
The Anopheles genus is a member of the Culicidae family and consists approximately 460 recognized species. composed 7 subgenera with diverse geographical distributions. Despite its huge medical importance, consensus has not been reached on phylogenetic relationships among subgenera. We assembled comprehensive dataset comprising COI, COII 5.8S rRNA genes used maximum likelihood Bayesian inference to estimate phylogeny divergence times six out seven Our analysis reveals monophyletic group...
Abstract The emergence of SARS-CoV-2 variants concern has prompted the need for near real-time genomic surveillance to inform public health interventions. In response this need, global scientific community, through unprecedented effort, sequenced and shared over 11 million genomes GISAID, as May 2022. This extraordinarily high sampling rate provides a unique opportunity track evolution virus in real-time. Here, we present outbreak.info, platform that currently tracks 40 combinations PANGO...
Abstract Sea turtles are the only extant chelonian representatives that inhabit marine environment. One key to successful colonization of this habitat is adaptation different energetic demands. Such requirement intrinsically related mitochondrial ability generate energy through oxidative phosphorylation (OXPHOS) process. Here, we estimated Testudines phylogenetic relationships from 90 complete genomes and tested adaptive evolution 13 protein-coding genes sea determine how natural selection...
Abstract The manatee family encompasses three extant congeneric species: Trichechus senegalensis (African manatee), T. inunguis (Amazonian and manatus (West Indian manatee). fossil record for manatees is scant, few phylogenetic studies have focused on their evolutionary history. We use full mitogenomes of all species to infer the divergence dates biogeographical histories these effect natural selection mitogenomes. complete mitochondrial genomes (16,851 bp), (16,882 comprise 13...
Abstract Background The blood-feeding behavior evolved multiple times in Insecta lineages and it represents an excellent opportunity to study patterns of convergent molecular evolution regarding this habit. In insects the expansion some gene families is linked with behavior, but a wide comparing these among different still missing. Here we gathered genomic data from six independently-evolved hematophagous lineages, aiming identify expansions and/or contractions insects. Results We found four...
Scorpion venoms are composed of several substances with different pharmacological activities. Neurotoxins exert their effects by targeting ion channels resulting in toxic to mammals, insects and crustaceans. Tb II-I, a fraction isolated from Tityus bahiensis scorpion venom, was investigated for its ability induce neurological immune-inflammatory effects. Two putative β-sodium channel toxins were identified this fraction, Tb2 II 4, the latter having been completely sequenced mass...
The phylogeography of the holoplanktonic chaetognath Flaccisagitta enflata was investigated in Tropical Western Atlantic (TWA). Considering cosmopolitan range this species and fact that its entire life cycle is planktonic, central hypothesis study F. exhibits connectivity due to high dispersal capacity, forming a panmictic population among sites. evaluated areas included neritic (Port Recife-PR, Tamandaré - TA) oceanic (Fernando de Noronha Archipelago-FN, Rocas Atoll-RA, Guará seamount-GS...
The multispecies coalescent (MSC) has been increasingly used in phylogenomic analyses due to the accommodation of gene tree topological heterogeneity by taking into account population-level processes, such as incomplete lineage sorting. In this sense, phylogeny insect species, which are characterized their large effective population sizes, is suitable for a coalescent-based analysis. Furthermore, studies so far recovered short internal branches at early divergences life, indicating fast...
The genus Plocamium encompasses seaweeds that are widely distributed throughout the world’s oceans, with brasiliense found along tropical and subtropical coasts of Western Atlantic. This wide distribution can lead to structured populations due environmental differences (e.g., light levels or temperature), restricted gene flow, presence cryptic species. Abiotic variation also affect expression, which consequently leads in protein profile. study aimed analyze genetic proteomic profiles P....
Abstract Arbovirus surveillance of wild-caught mosquitoes is an affordable and sensitive means monitoring virus transmission dynamics at various spatial-temporal scales, emergence re-emergence during epidemic interepidemic periods. A variety molecular diagnostics for arbovirus screening (known as xeno-monitoring) are available, but most provide limited information about diversity. PCR-based coupled with metatranscriptomics increasingly pipeline integrating complete viral genome sequencing...