Li Huang

ORCID: 0000-0002-8826-8663
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About
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Research Areas
  • Gestational Diabetes Research and Management
  • Pregnancy and preeclampsia studies
  • Birth, Development, and Health
  • Breastfeeding Practices and Influences
  • Folate and B Vitamins Research
  • Air Quality and Health Impacts
  • Neonatal Respiratory Health Research
  • Infant Nutrition and Health
  • Pediatric health and respiratory diseases
  • Diet and metabolism studies
  • Climate Change and Health Impacts
  • Selenium in Biological Systems
  • Pregnancy and Medication Impact
  • Reproductive System and Pregnancy
  • Smoking Behavior and Cessation
  • Heavy Metal Exposure and Toxicity
  • Air Quality Monitoring and Forecasting
  • Iron Metabolism and Disorders
  • Nutritional Studies and Diet
  • Vitamin D Research Studies
  • Obesity, Physical Activity, Diet
  • Cancer-related molecular mechanisms research
  • Fluoride Effects and Removal
  • Thallium and Germanium Studies
  • Frailty in Older Adults

Sichuan University
2023-2025

Affiliated Hospital of Southwest Medical University
2025

Huazhong University of Science and Technology
2011-2024

Chengdu University of Traditional Chinese Medicine
2024

Tongji Hospital
2023

Ningbo University
2023

Chongqing Maternal and Child Health Hospital
2021

Wuhan University
2019-2020

Zhengzhou University
2020

303 Hospital of People's Liberation Army
2014

A growing number of epidemiologic studies have estimated associations between type 2 diabetes mellitus and exposure to metals. However, on the internal assessments metal gestational (GDM) are limited in scope inconsistent outcomes.This investigation aimed explore urinary nickel (Ni), arsenic (As), cadmium (Cd), antimony (Sb), cobalt (Co), or vanadium (V) early pregnancy subsequent risk GDM Chinese pregnant women.The study population included 2090 women with singleton from Tongji Maternal...

10.1016/j.envint.2019.105370 article EN cc-by-nc-nd Environment International 2019-12-18

The association between iron supplementation and gestational diabetes mellitus (GDM) is still inconclusive, this has not been extensively studied in relation to plasma ferritin the early second trimester. We aimed prospectively examine independent combined associations of concentrations supplement use with GDM. 2117 women from Tongji Maternal Child Health Cohort Wuhan, China. Plasma around 16 weeks' gestation was measured by ELISA kits information on collected questionnaires. GDM diagnosed a...

10.1093/ajcn/nqab162 article EN publisher-specific-oa American Journal of Clinical Nutrition 2021-04-22

The multi-center randomized phase 3 NHL-004 study compared etoposide, dexamethasone and pegaspargase (ESA) versus methotrexate, (MESA) regimen, combined with sandwiched radiotherapy, in newly diagnosed early-stage nasal natural killer/T-cell lymphoma (NKTCL). Here we report the long-term outcomes (median follow-up, 64 months) biomarker analysis. 256 eligible patients aged 14-70 years were randomly assigned (1:1) to ESA or MESA arm. 5-year progression-free survival (PFS) rates 80.3% 74.9%...

10.3324/haematol.2025.287513 article EN cc-by-nc Haematologica 2025-04-10

Abstract Vitamin D deficiency has been reported to be associated with respiratory tract infection (RTI). However, evidence regarding the effects of vitamin supplementation on susceptibility infants RTI is limited. In this prospective birth cohort study, we examined whether reduced risk in 2,244 completing follow‐up from 6 months age. The outcome endpoint was first episode paediatrician‐diagnosed or age when no event occurred. Infants receiving supplements at a daily dose 400–600 IU were...

10.1111/mcn.12987 article EN cc-by Maternal and Child Nutrition 2020-03-05

Current results regarding the effect of folic acid (FA) supplement use on gestational hypertension (GH) and preeclampsia are limited inconsistent. We aimed to investigate whether FA was associated with GH preeclampsia. Participants from Tongji Maternal Child Health Cohort information periconceptional diagnosis GH/preeclampsia were included (n=4853). Robust Poisson regression used assess association Among 4853 participants in this study, 1161 (23.9%) 161 (3.3%) women diagnosed preeclampsia,...

10.1161/hypertensionaha.119.14621 article EN Hypertension 2020-05-11

Investigators in previous studies have drawn inconsistent conclusions regarding the relationship between relatively low exposure to fine particulate matter (particulate with an aerodynamic diameter ≤2.5 μm (PM2.5)) and risk of gestational diabetes mellitus (GDM), while association high PM2.5 GDM has not been well studied. We investigated during pregnancy blood glucose levels Chinese women. The present study was conducted from August 2013 May 2016 among 3,967 pregnant women Tongji Maternal...

10.1093/aje/kwaa056 article EN American Journal of Epidemiology 2020-04-10

Compliance with dietary guidelines among pregnant women can positively influence not only their own health but also the of babies. Measuring compliance requires professional skills in nutrition and counseling. In China, few simple effective techniques assess quality women, especially rural areas. We aimed to establish a new assessment technique, "Chinese Dietary Guidelines Index for Pregnant Women (CDGCI-PW)" association between maternal risks pregnancy complications.The CDGCI-PW consists 13...

10.3390/nu13030829 article EN Nutrients 2021-03-03

Antimony (Sb) has been associated with type 2 diabetes in previous studies. However, the role of Sb incidence Gestational mellitus (GDM) remains unclear.We investigated association between exposure during early pregnancy and risk GDM.We performed a prospective study 2093 pregnant women from Tongji Maternal Child Health Cohort (TMCHC). concentrations were measured urine samples by ICP-MS. The urinary concentration GDM was assessed using robust Poisson regression model after adjustment for...

10.1016/j.envint.2018.11.072 article EN cc-by-nc-nd Environment International 2018-12-05

Manganese (Mn) intake has been found to be linked with risk of type 2 diabetes. However, the role Mn in development gestational diabetes mellitus (GDM) remains investigated. This prospective study included pregnant women from Tongji Maternal and Child Health Cohort. A total 2327 participants plasma specimens before 20 weeks were included. Among women, 9.7% (225/2327) diagnosed GDM. After adjustment, third highest quartile levels had 1.31-fold (RR, 2.31 [1.48, 3.61]) 2.35-fold 3.35 [2.17,...

10.1021/acs.est.2c03330 article EN Environmental Science & Technology 2022-10-10

Anoikis is a distinct type of programmed cell death and unique mechanism for tumor progress. However, its exact function in gastric cancer (GC) remains unknown. This study aims to investigate the anoikis-related lncRNA (ar-lncRNA) prognosis GC immunological infiltration. The ar-lncRNAs were derived from RNA sequencing data associated clinical information obtained Cancer Genome Atlas. Pearson correlation analysis, differential screening, LASSO Cox regression utilized identify typical with...

10.3390/bioengineering11090893 article EN cc-by Bioengineering 2024-09-05

To examine the causal associations of diet-derived circulating antioxidants with knee osteoarthritis (OA), hip OA, and rheumatoid arthritis (RA) within two-sample Mendelian randomization (MR) framework.Independent single-nucleotide polymorphisms (SNPs) significantly associated levels (retinol, β-carotene, lycopene, vitamin C E) were extracted as genetic instruments. Summary statistics instruments RA obtained from corresponding genome-wide association studies (GWASs). The inverse-variance...

10.3389/fmed.2023.1147365 article EN cc-by Frontiers in Medicine 2023-06-21

Abstract We aimed to assess protein nutrition status during pregnancy by maternal plasma total (MTP) levels in urban pregnant women and explore the association between trimester‐specific MTP risk of preterm birth (PTB). A prospective design was conducted 3,382 mother‐newborn pairs with second‐trimester information 3,478 third‐trimester information. Multiple Cox proportional hazard regression multiple linear were used analyse associations PTB as well gestational duration, respectively. Nearly...

10.1111/mcn.13043 article EN Maternal and Child Nutrition 2020-08-20

<h3>Objectives</h3> To examine the relationship between prenatal nitrogen dioxide (NO<sub>2</sub>) exposure and foetal growth in a prospective cohort of 1001 Chinese women. <h3>Methods</h3> The maternal NO<sub>2</sub> levels were estimated using land-use regression models based on home address. biparietal diameter (BPD), head circumference (HC), abdominal (AC), femur length (FL) weight (EFW) evaluated via ultrasonography. multiple linear model was used to adjust for confounders, mixed-effect...

10.1136/oemed-2016-103980 article EN Occupational and Environmental Medicine 2017-01-06

Abstract The high overall plant-based diet index (PDI) is considered to protect against type 2 diabetes in the general population. However, whether PDI affects gestational mellitus (GDM) risk among pregnant women still unclear. We evaluated association between and GDM based on a Chinese large prospective cohort – Tongji Maternal Child Health Cohort. Dietary data were collected at 13–28 weeks of pregnancy by validated semi-quantitative FFQ. was obtained assigning plant food groups positive...

10.1017/s0007114521000234 article EN British Journal Of Nutrition 2021-01-20
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