Liu Jian

ORCID: 0000-0002-8889-172X
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Cancer, Lipids, and Metabolism
  • Bladder and Urothelial Cancer Treatments
  • Cardiac Ischemia and Reperfusion
  • Lipoproteins and Cardiovascular Health
  • Cardiac Fibrosis and Remodeling
  • Gallbladder and Bile Duct Disorders
  • Intracranial Aneurysms: Treatment and Complications
  • Atherosclerosis and Cardiovascular Diseases
  • PARP inhibition in cancer therapy
  • Atrial Fibrillation Management and Outcomes
  • Phytochemistry and Biological Activities
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Inflammation biomarkers and pathways
  • Medicinal Plant Pharmacodynamics Research
  • Bioactive natural compounds
  • Plasma Applications and Diagnostics
  • Body Contouring and Surgery
  • Spinal Fractures and Fixation Techniques
  • Diet and metabolism studies
  • Abdominal vascular conditions and treatments
  • Coronary Interventions and Diagnostics
  • Cholesterol and Lipid Metabolism
  • Bariatric Surgery and Outcomes
  • Cervical and Thoracic Myelopathy

Chinese Academy of Fishery Sciences
2023

Nantong University
2020

Chongqing Medical University
2009-2019

The Affiliated Yongchuan Hospital of Chongqing Medical University
2009-2019

Chengdu Fifth People's Hospital
2019

Hefei University of Technology
2018

Henan Provincial People's Hospital
2013

Cardiovascular Research Foundation
2009

Columbia University Irving Medical Center
2009

Ganzhou People's Hospital
2009

Statins are widely used in patients with cardiovascular diseases. A considerable number of previous studies revealed that the intracellular signaling transforming growth factor (TGF)‑β1 mediated development cardiomyocyte hypertrophy and interstitial fibrosis. However, whether statins can ameliorate ventricular remodeling post‑myocardial infarction via TGF‑β1 pathway remains to be rigorously tested. The left anterior descending artery was ligated induce a rat model myocardial infarction....

10.3892/mmr.2016.5178 article EN cc-by-nc-nd Molecular Medicine Reports 2016-04-25

The stems of Dendrobium huoshanense have long been used to prevent various diseases, including inflammatory diseases. This study was aimed explain the anti-inflammatory effect D. in LPS-induced RAW 264.7 macrophages and discover potential compounds. Results exhibited that ethanol extract could significantly inhibit production NO, TNF-α IL-1β. Based on bioassay guided strategy, four bibenzyls (1–4) were isolated from for first time. Anti-inflammatory assay showed 1–4 remarkably NO...

10.1080/14786419.2018.1489394 article EN Natural Product Research 2018-11-03

Abstract From May 2003 to 2010, a total of 9 patients with severe hemobilia after percutaneous transhepatic cholangial drainage (PTCD) were diagnosed using superselective angiography and cholangiography, then treated interventional procedures. Two hepatic arterio-biliary fistula underwent proximal distal arterial embolization the responsible vessel. Six pseudoaneurysm had occlusion embolization. Another patient biliary-portal vein received biliary fully covered stent placement. The effects...

10.9738/intsurg-d-13-cc194 article EN International Surgery 2013-08-01

Statins exert pleiotropic effects on endothelial cells in addition to lowering cholesterol. 15-Lipoxygenase-1 (ALOX15) has been implicated vascular inflammation and disease. The relationship between atorvastatin ALOX15 was investigated using a rat carotid artery balloon-injury model. Hematoxylin eosin (HE) staining showed that overexpression increased the thickness of intima-media (IMT). Immunohistochemistry western blotting expression cellular adhesion molecules (CAMs) but decreased nitric...

10.1155/2016/6769032 article EN cc-by Mediators of Inflammation 2016-01-01

Laparoscopic bariatric surgery is necessary for obese patients who cannot control body weight through daily diet and exercise, or other non-surgical ways. Three kinds of laparoscopic surgery, namely Roux-en-Y gastric bypass, sleeve gastrectomy, gastrectomy with jejunal are available loss in clinical practice, but their comparative effects unclear. In this study, these were compared to illustrate effects.A case-control study was conducted on 175 participants fulfilled the inclusion criteria...

10.1007/s13300-019-00719-7 article EN cc-by-nc Diabetes Therapy 2019-12-03

Cholesterol has been used as additive in fish feeds due to the reduced use of meal and oil. In order evaluate effects dietary cholesterol supplementation (D-CHO-S) on physiology, a liver transcriptome analysis was performed following feeding experiment turbot tiger puffer with different levels cholesterol. The control diet contained 30% (0% oil) without supplementation, while treatment supplemented 1.0% (CHO-1.0). A total 722 581 differentially expressed genes (DEG) between groups were...

10.1155/2023/2308669 article EN cc-by Aquaculture Nutrition 2023-06-05

<h3>Objectives</h3> 15-Lipoxygenase-1(15-LO) oxidises polyunsaturated fatty acids to a rich spectrum of biologically active metabolites, and its deregulation has been reported involved in the development atherosclerosis. A series studies demonstrated atorvastatin attenuates endothelial dysfunction. But relationship between 15-LO not fully investigated. The goal our study was evaluate whether improvement function by atorvastatin. <h3>Methods</h3> model oxidised low-density lipoprotein...

10.1136/heartjnl-2013-304613.197 article EN Heart 2013-08-01

<h3>Objectives</h3> To investigate the effects of Exendin-4 (Ex-4) on nitric oxide (NO) produced bypig iliac endothelium cells (PIEC) and relationship with intracellular calcium ions change. <h3>Methods</h3> GLP-1receptor (GLP-1R) in PIEC membrane was detected by immunofluorescence. were cultured RPMI 1640 (with calcium)/DMEM (non calcium) nutrient mediumseparately treated various concentrations Ex-4. NO production concentration measured using Griess reaction cell culture supernatants...

10.1136/heartjnl-2012-302920b.11 article EN Heart 2012-10-01
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