A5019286155- Genomics and Chromatin Dynamics
- Biochemical Analysis and Sensing Techniques
- Plant Molecular Biology Research
- RNA modifications and cancer
- Insect Utilization and Effects
- Epigenetics and DNA Methylation
- Agriculture Market Analysis Ukraine
- Regulation of Appetite and Obesity
- Olfactory and Sensory Function Studies
- Papaya Research and Applications
- Silkworms and Sericulture Research
- Insect Resistance and Genetics
- Nutrition, Genetics, and Disease
- Neurobiology and Insect Physiology Research
University of Michigan–Ann Arbor
2022-2024
Sungkyunkwan University
2024
Highlights•Sucrose consumption showed specific and selective effects on the peripheral taste system•Dietary sugar lowered chorda tympany responses to sucrose number of PLCβ2+ cells•Responses other sensory qualities modalities were largely unaffected•We observed that phenotypes restored after was removed from dietSummaryElevated is associated with an increased risk for metabolic diseases. Whereas evidence humans, rodents, insects suggests dietary modifies sweet sensation, understanding nerve...
Appropriate ingestion of salt is essential for physiological processes such as ionic homeostasis and neuronal activity. Generally, low concentrations elicit attraction, while high aversive responses. Here, we observed that sugar neurons in the L sensilla
Diet profoundly influences brain physiology, but how metabolic information is transmuted into neural activity and behavior changes remains elusive. Here, we show that the enzyme O-GlcNAc Transferase (OGT) moonlights on chromatin of D. melanogaster gustatory neurons to instruct in accessibility transcription underlie sensory adaptations a high-sugar diet. OGT works synergistically with Mitogen Activated Kinase/Extracellular signal Regulated Kinase (MAPK/ERK) rolled its effector stripe (also...
ABSTRACT The Arc genes — which include Drosophila Arc1 and Arc2 ( dArc ) evolved from Ty3 retrotransposons encode proteins that form virus-like capsids. These capsids enable a novel of intercellular communication by transferring RNAs between cells. However, the specific neuronal circuits brain processes signaling regulates remain unknown. Here, we show loss both in melanogaster enhances associative learning an appetitive conditioning paradigm, where flies associate odor with sugar rewards....
Abstract Diet profoundly influences brain physiology, but how nutritional information is transmuted into neural activity and behavior changes remains elusive. Here we show that the metabolic enzyme O-GlcNAc Transferase (OGT) moonlights on chromatin of D. melanogaster gustatory neurons to instruct in accessibility transcription underlie sensory adaptations a high sugar diet. OGT works synergistically with Mitogen Activated Kinase/Extracellular signal Regulated Kinase (MAPK/ERK) rolled its...