A5062354191- Toxoplasma gondii Research Studies
- Autophagy in Disease and Therapy
- Cytomegalovirus and herpesvirus research
- Animal health and immunology
- Herpesvirus Infections and Treatments
- Rabbits: Nutrition, Reproduction, Health
- Aquaculture disease management and microbiota
- Anatomy and Medical Technology
- Polyamine Metabolism and Applications
- Sperm and Testicular Function
- IL-33, ST2, and ILC Pathways
- Bone Tumor Diagnosis and Treatments
- Cell death mechanisms and regulation
- Apelin-related biomedical research
- Probiotics and Fermented Foods
- Plasma Diagnostics and Applications
- Aquatic Invertebrate Ecology and Behavior
- Animal Nutrition and Physiology
- Infant Nutrition and Health
- Adipose Tissue and Metabolism
- Vector-borne infectious diseases
- Surgical Simulation and Training
- Reproductive Physiology in Livestock
- Invertebrate Immune Response Mechanisms
- Vitamin K Research Studies
University of Perugia
2014-2023
To investigate the ovulatory mechanisms triggered by raw semen (RS) in rabbits, we examined expression of nerve growth factor (NGF)—a supposed ovulation-inducing (OIF)—and cognate receptors anterior pituitary, ovary, and cervix as well plasma NGF luteinizing hormone (LH) concentrations. Six does/group were sham-inseminated with sterile saline (PBS), naturally mated (NM), inseminated RS alone or after lumbar anesthesia (ARS), treatment COX inhibitors (CIRS). Immunohistochemistry revealed...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder for which the current medical therapy not completely effective. Bovine colostrum (BC) biological fluid rich in bioactive molecules that may have beneficial effects on several gastrointestinal disorders. The objectives of this study were to assess preventive BC supplementation mouse model 2,4,6 trinitrobenzene sulfonic acid (TNBS)-induced colitis using multidisciplinary approach. Specifically, following parameters evaluated:...
Abstract Toxoplasma gondii infects a broad range of hosts and can establish chronic infections with the formation brain cysts. Infected animals show altered risk behaviour which has been suggested to increase capture probability hosts, thus enhance parasite transmission. It proposed that ability cysts secrete tyrosine hydroxylase could mediate these behavioural alterations. We tested involvement secreted hydroxylase, coded by AaaH2 gene, in development alterations mouse behaviour, generating...
This study investigated the effects of a short-term administration bovine colostrum (BC) in TNBS model induced colitis. Colitis was by treatment after seven days BC (BC group, n = 12) or saline (control mice. Clinical signs, histopathological characteristics, expression levels Toll-like receptor 4 (TLR4), pro- and anti-inflammatory cytokines, microbial composition were assessed. well tolerated did not induce any histological damage clinical symptoms. After treatment, group showed reduction...
To gain access to the intracellular cytoplasmic niche essential for their growth and replication, apicomplexan parasites such as Toxoplasma gondii rely on timely secretion of two types apical organelles named micronemes rhoptries. Rhoptry proteins are key host cell invasion remodeling, however, molecular mechanisms underlying tight control rhoptry discharge poorly understood. Here, we report identification functional characterization novel T. thrombospondin-related implicated in exocytosis....
is a protozoan parasite that infects broad spectrum of hosts and can colonize many organs cell types. The ability to reside within wide range different niches requires substantial adaptability diverse microenvironments. Very little known about how this senses various milieus adapts its metabolism survive, replicate during the acute stage, then differentiate chronic stage.
Abstract Toxoplasma gondii is a protozoan parasite that infects broad spectrum of hosts and can colonize many organs cell types. The ability to reside within wide range different niches requires substantial adaptability diverse microenvironments. Very little known about how this senses various milieus adapts its metabolism survive, replicate during the acute stage, then differentiate chronic stage. Most eukaryotes, from yeast mammals, rely on nutrient sensing machinery involving TORC complex...
ABSTRACT To gain access to the intracellular cytoplasmic niche essential for their growth and replication, apicomplexan parasites such as Toxoplasma gondii rely on timely secretion of two types apical organelles named micronemes rhoptries. Rhoptry proteins are key host cell invasion remodelling, however, molecular mechanisms underlying thight control rhoptry discharge poorly understood. Here, we report identification functional characterization novel T. thrombospondin-related implicated in...