Fangfei Li

ORCID: 0000-0002-9108-809X
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Research Areas
  • Parkinson's Disease Mechanisms and Treatments
  • Acute Ischemic Stroke Management
  • Ginkgo biloba and Cashew Applications
  • Inflammatory mediators and NSAID effects
  • RNA regulation and disease
  • Reproductive System and Pregnancy
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Vascular Malformations Diagnosis and Treatment
  • Malaria Research and Control
  • Chemotherapy-related skin toxicity
  • Computational Drug Discovery Methods
  • Mosquito-borne diseases and control
  • Venous Thromboembolism Diagnosis and Management
  • Leprosy Research and Treatment
  • Tryptophan and brain disorders
  • Cancer Research and Treatments
  • Sarcoma Diagnosis and Treatment
  • Medical Research and Treatments
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Advanced biosensing and bioanalysis techniques
  • Chemokine receptors and signaling
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Synthesis and Biological Evaluation
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms

Chongqing Cancer Hospital
2018-2024

Chongqing University
2018-2024

Xinqiao Hospital
2021-2022

Army Medical University
2014-2022

First Affiliated Hospital of Jinan University
2022

Capital Medical University
2015-2021

Dalian Medical University
2020

General Hospital of Shenyang Military Region
2020

Shenyang Pharmaceutical University
2018

Hong Kong Baptist University
2016

The minimum inhibitory concentrations (MIC) of a series synthetic inert polypyridylruthenium(II) complexes against four strains bacteria – Gram positive Staphylococcus aureus (S. aureus) and methicillin-resistant S. (MRSA), negative Escherichia coli (E. coli) Pseudomonas aeruginosa (P. aeruginosa) have been determined. results demonstrate that for the dinuclear ruthenium(II) ΔΔ/ΛΛ-[{Ru(phen)2}2{μ-bbn}]4+ {where phen = 1,10-phenanthroline; bbn bis[4(4′-methyl-2,2′-bipyridyl)]-1,n-alkane (n 2,...

10.1039/c1dt10250h article EN Dalton Transactions 2011-01-01

This study aimed to analyze the impact of baseline posterior circulation Acute Stroke Prognosis Early Computed Tomography Score (pc-ASPECTS) on efficacy and safety endovascular therapy (EVT) for patients with acute basilar artery occlusion. The BASILAR was a nationwide prospective registry consecutive symptomatic radiologically confirmed occlusion within 24 hours symptom onset. We estimated effect standard medical alone (SMT group) versus SMT plus EVT (EVT documented pc-ASPECTS noncontrast...

10.1161/strokeaha.120.031371 article EN Stroke 2021-02-11

A series of polypyridyl-ruthenium(II) and -iridium(III) complexes that contain labile chlorido ligands, [{M(tpy)Cl}2{μ-bbn}]2/4+ {Cl-Mbbn; where M = Ru or Ir; tpy 2,2′:6′,2′′-terpyridine; bbn bis[4(4′-methyl-2,2′-bipyridyl)]-1,n-alkane (n 7, 12 16)} have been synthesised their potential as antimicrobial agents examined. The minimum inhibitory concentrations (MIC) bactericidal (MBC) the metal against four strains bacteria – Gram positive Staphylococcus aureus (S. aureus) methicillin-resistant...

10.1039/c3dt32775b article EN Dalton Transactions 2013-01-01

To assess the suitability of deep medullary vein visibility in susceptibility weighted imaging-magnetic resonance imaging studies as a method for diagnosis and evaluation cerebral small vessel disease progression.A total 92 patients with CSVD were enrolled baseline clinical data reviewed retrospectively. Neuroimaging biomarkers including high-grade white matter hyperintensity (HWMH), microbleed (CMB), enlarged perivascular space (PVS), lacunar infarct (LI) identified burden was calculated....

10.3389/fnagi.2020.597799 article EN cc-by Frontiers in Aging Neuroscience 2020-12-01

Abstract Background Clopidogrel is an antiplatelet drug used in the treatment of ischemic stroke. Safety and efficacy clopidogrel has been confirmed CAPRIE, PRoFESS trials. However, these studies focused on patients aged less than 75 years. CYP2C19 polymorphisms resulted individual differences response. Our objective was to determine whether elderly stroke over years would benefit from CYP2C19-genotype-guided strategy for secondary prevention Methods A retrospective analysis or older with...

10.1186/s12883-021-02127-6 article EN cc-by BMC Neurology 2021-03-09

To analyze peripheral blood interleukin 6 (IL-6) methylation status and its clinical significance in patients with systemic lupus erythematosus (SLE).Blood samples from 41 adult SLE, 20 healthy controls were collected. The of IL-6 was determined by specific polymerase chain reaction (MSP). expression detected real-time PCR. Correlations between features or laboratory findings SLE investigated.The could reflect the level mononucleated cells (PBMCs) SLE. Significantly positive correlation...

10.5114/ceji.2014.43724 article EN cc-by-nc-nd Central European Journal of Immunology 2014-01-01

Ischemic stroke is related to inflammation. We investigated leukocyte counts, neutrophil and NLR (neutrophil-to-lymphocyte ratio) explore their prognostic potential determine if high counts before endovascular treatment (EVT) in patients with acute basilar artery occlusion (BAO) are associated worse outcomes at 90 days post-EVT.Leukocyte were determined eligible from the Acute Basilar Artery Occlusion Study (BASILAR). Patients divided into four groups according quartiles. The primary outcome...

10.3389/fnagi.2022.978740 article EN cc-by Frontiers in Aging Neuroscience 2022-09-01

BACKGROUND Pancreatic ductal adenocarcinoma (PDAC) is a common cancer with increasing morbidity and mortality due to changes of social environment. AIM To evaluate the significance serum carbohydrate antigen 19-9 (CA19-9) tumor size pre- post-neoadjuvant therapy (NAT). METHODS This retrospective study was conducted at Chongqing Key Laboratory Translational Research for Cancer Metastasis Individualized Treatment, University Hospital. specifically assessed CA19-9 levels before after NAT....

10.4251/wjgo.v16.i3.798 article EN World Journal of Gastrointestinal Oncology 2024-03-12

10.1016/j.wjam.2018.08.001 article EN World Journal of Acupuncture - Moxibustion 2018-08-28

Objective To investigate the function of CXCR4 and CXCR7 receptors expressed in bone marrow mesenchymal stem cells (BMSCs) membrane surface process cell migration,in order to provide a theoretical basis for trauma repair.Methods C57BL/6 mice were selected collect BMSCs second passage after using adherence culture method.Expressions on detected immunofluorescent staining flow cytometry.In CXCL12-induced chemotaxis BMSCs,the assay was divided into control group (cells seeded serum-free...

10.3760/cma.j.issn.1001-8050.2014.12.17 article EN Zhonghua chuangshang zazhi 2014-12-15

Objective To observe the effect of Tingli-Dazao-Xiefei decoction combined with chemotherapy in treatment lung cancer pleural effusion. Methods A total 90 patients who met inclusion criteria from January to June 2017, were randomly divided into group and control group. All treated intrapleural administration cisplatin once a week, while received additional taking daily. Changes clinical efficacy, traditional Chinese medical (TCM) symptom score Karnofsky observed 4 weeks...

10.3760/cma.j.issn.1673-4246.2018.03.006 article EN Traditional Chinese Medicine 2018-03-30
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