A5100348118- Anesthesia and Pain Management
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Enhanced Recovery After Surgery
- Gastric Cancer Management and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Pain Mechanisms and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Lipoproteins and Cardiovascular Health
- Pain Management and Opioid Use
- Cardiac, Anesthesia and Surgical Outcomes
- Pediatric Pain Management Techniques
- Musculoskeletal synovial abnormalities and treatments
- Pharmaceutical Economics and Policy
- Nausea and vomiting management
- Olfactory and Sensory Function Studies
- Musculoskeletal pain and rehabilitation
- Colorectal Cancer Surgical Treatments
- Bariatric Surgery and Outcomes
- Head and Neck Anomalies
- Music Therapy and Health
- Berberine and alkaloids research
- Body Contouring and Surgery
- Biological and pharmacological studies of plants
- Health, Environment, Cognitive Aging
Shanghai Institute of Hematology
2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Zhongshan Hospital
2024
Fudan University
2024
Sun Yat-sen University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2024
University of Hong Kong
2024
Peking Union Medical College Hospital
2019-2024
Chengdu University of Traditional Chinese Medicine
2021-2023
Daiichi Sankyo (United States)
2013-2022
Painful diabetic neuropathy (PDN) is a common complication of diabetes mellitus and adversely affects the patients' quality life. Evidence has accumulated that PDN associated with hyperexcitability peripheral nociceptive primary sensory neurons. However, precise cellular mechanism underlying remains elusive. This may result in lacking effective therapies for treatment PDN. The phenolic glucoside, gastrodin, which main constituent Chinese herbal medicine Gastrodia elata Blume, been widely...
Brain-derived neurotrophic factor (BDNF) is one of the proteins that contributes to survival, growth, maintenance neurons, and plays important roles in pathophysiology depression. It has been reported depression closely associated with pathogenesis acne vulgaris disease. But, there no report serum BDNF levels patients vulgaris. The study aimed determine potential association between depressive symptoms young adults vulgaris.In this analytical cross-sectional study, were measured peripheral...
Background and purpose — The ENLIVEN trial showed that, after 25 weeks, pexidartinib statistically significantly reduced tumor size more than placebo in patients with symptomatic, advanced tenosynovial giant cell (TGCT) for whom surgery was not recommended. Here, we detail the effect of on patient-reported physical function stiffness ENLIVEN. Patients methods This a planned analysis outcome data from ENLIVEN, doubleblinded, randomized phase 3 adults TGCT treated or placebo. Physical assessed...
Abstract Background The double-blind, randomized, placebo-controlled phase 3 study of orally administered PLX3397 in patients with pigmented villonodular synovitis or giant cell tumor the tendon sheath (ENLIVEN) showed that pexidartinib provides a robust objective response adults tenosynovial tumors (TGCT) not amenable to improvement surgery. Based on these results, 2019, received accelerated approval United States this population as breakthrough therapy under an orphan drug designation....
Coronary heart disease (CHD) is a major public health problem in the United States. It has been well recognized that patients with prior CHD are at very high risk for recurrent CHD. Statins have recommended as an effective treatment secondary prevention of CHD.To (1) determine proportion who received outpatient statin therapy after hospitalization and (2) identify factors associated initiation use.Using MedStat MarketScan 1999-2003 databases, hospitalizations (ICD-9-CM codes 410.xx-414.xx,...
Staphylococcus aureus is an opportunistic pathogen. Due to the widespread use and abuse of antibiotics, various drug-resistant strains S. have emerged, with methicillin-resistant (MRSA) being most prevalent. Bacterial biofilm a significant contributor bacterial infection drug resistance. Consequently, formation has emerged as therapeutic strategy. In this study, chemical constituents, antimicrobial antibiofilm properties tannins isolated from Penthorum chinense Pursh (TPCP) were...
In the social context of “Educational Involution”, educational expectations parents have a potential influence on development children. High parental create anxiety, which in turn results rise involvement and eventually promotes growth progress The current study administered an electronic questionnaire to 891 young children four provinces China. included Parental Educational Expectations Scale, Anxiety Involvement Child Development Scale. This used SPSS 27.0 for statistical data analysis...
Background: Persistent treatment with lipid-lowering therapies is important for achieving optimal clinical outcomes. To date, no study has evaluated the real-world use of colesevelam and factors associated persistent treatment. Objective: The primary objective this was to examine patient demographic characteristics in practice. Methods: In retrospective cohort study, adult patients hypercholesterolemia, an initial order between January 2004 December 2011, a low-density lipoprotein...
The study aimed to investigate the predictive value of dynamic contrast-enhanced ultrasound (DCE-US) in differentiating small-duct (SD) and large-duct (LD) types intrahepatic cholangiocarcinoma (ICC). This retrospectively enrolled 110 patients with pathologically confirmed ICC lesions who were subject preoperative (CEUS) examinations between January 2022 February 2023. Patients further classified according subtype: SD-type LD-type, an optimal model was established validated using above pilot...
e16103 Background: Surgery combined with perioperative therapy was recommended as standard treatment for patients locally advanced esophagogastric junction (EGJ) adenocarcinoma, but the survival rate still poor. Immunotherapy has shown antitumor activity and an acceptable safety profile in EGJ cancer. The aim of this study to evaluate efficacy neoadjuvant Serplulimab concurrent chemoradiotherapy previously untreated resectable adenocarcinoma. Methods: Eligible EGJ(Siewert Type II III,...
Objective To analyze the effectiveness and safety of laparoscopic sleeve gastrectomy (LSG) in treating obesity its co-morbidities.Methods The clinical data obese patients undergoing LSG Peking Union Medical College Hospital from August 2012 to 2017 were retrospectively analyzed. Medium-term outcome measures included excess weight loss (%EWL),co-morbidity improvement,and complications.Results Seventy-five comprising 28 men[ body mass index(BMI):(47.3±7.5)kg/m 2) ] 47 women [BMI (41.1±7.0)...
OPINION article Front. Psychiatry, 15 April 2022Sec. Anxiety and Stress Disorders https://doi.org/10.3389/fpsyt.2022.854857