A5102747320- CRISPR and Genetic Engineering
- Vibration Control and Rheological Fluids
- Photosynthetic Processes and Mechanisms
- Algal biology and biofuel production
- Antioxidant Activity and Oxidative Stress
- Pulmonary Hypertension Research and Treatments
- Cancer-related molecular mechanisms research
- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Structural Engineering and Vibration Analysis
- Seismic Performance and Analysis
- Plant Gene Expression Analysis
- Semiconductor materials and devices
- Elevator Systems and Control
- Plant Molecular Biology Research
- Insect Resistance and Genetics
- Plant Stress Responses and Tolerance
- Circular RNAs in diseases
- Entomopathogenic Microorganisms in Pest Control
- Anaerobic Digestion and Biogas Production
- Green IT and Sustainability
- Nanomaterials and Printing Technologies
- Frequency Control in Power Systems
- Inflammasome and immune disorders
- Transplantation: Methods and Outcomes
Harbin Medical University
2022-2024
Chengdu Third People's Hospital
2024
Southwest Jiaotong University
2024
Northeast Agricultural University
2018-2024
Ministry of Agriculture and Rural Affairs
2024
Harbin Institute of Technology
2007-2023
Jilin Agricultural University
2021-2022
Daqing City People's Hospital
2022
Center for Life Sciences
2017
Shanghai Chengtou (China)
1982
Abstract Background Pyroptosis is a form of programmed cell death involved in the pathophysiological progression hypoxic pulmonary hypertension (HPH). Emerging evidence suggests that N6-methyladenosine (m6A)-modified transcripts long noncoding RNAs (lncRNAs) are important regulators participate many diseases. However, whether m6A modified lncRNAs can regulate pyroptosis HPH remains unexplored. Methods The expression levels FENDRR artery endothelial cells (HPAECs) were detected by using...
Background: Circular RNAs (circRNAs) have been implicated in pulmonary hypertension progression through largely unknown mechanisms. Pulmonary artery endothelial cell (PAEC) dysfunction is a hallmark the pathogenesis of hypertension. However, specific role circular PAEC injury caused by hypoxia remains unclear. Methods: In this study, using Western blotting, RNA pull down, Dual-luciferase reporter assay, immunohistochemistry, and immunofluorescence, we identified novel derived from...
Chinese cabbage (Brassica rapa L. ssp. pekinensis) is a widely cultivated and economically important vegetable crop with typical leaf curvature. The TCP (Teosinte branched1, Cycloidea, Proliferating cell factor) family proteins are plant-specific transcription factors (TFs) play roles in many plant biological processes, especially the regulation of In this study, 39 genes encoding TFs detected on whole genome B. rapa. Based phylogenetic analysis TCPs between Arabidopsis thaliana Brassica...
Excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) is the main cause hypoxic hypertension (PH), and mitochondrial homeostasis plays a crucial role. However, specific molecular regulatory mechanism function in PASMCs remains unclear.
The type III CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated genes) systems are bacterially encoded adaptive immune for defense against invading nucleic acids. They accomplish this task through the coordinated cleavage of substrates single-stranded RNA and DNA (ssDNA ssRNA) by Csm (type III-A) or Cmr III-B) effector complexes. ssRNA is complementarily bound to CRISPR (crRNA). However, structural basis DNase RNase activation nucleoprotein complex...
Abstract CD36 may defect on platelets and/or monocytes in healthy individuals, which was defined as deficiency. However, we did not know the correlation between molecular and protein levels completely. Here, aim to determine polymorphisms of gene, RNA level, plasma. The individuals were sequenced by Sanger sequencing. Bioinformational analysis used HotMuSiC, CUPSAT, SAAFEC-SEQ, FoldX. detection performed qPCR, flow cytometry, ELISA. In this study, found c.1228_1239 del ATTGTGCCTATT (allele...
Tomato is one of the most popular and nutritious vegetables worldwide, but their production quality are threatened by various stresses in environment which they grown. Thus, resistance tolerance tomatoes to biotic abiotic should be improved. Aldo-keto reductases (AKR) a superfamily NAD(P)(H)-dependent oxidoreductases that play multiple roles stress defenses detoxification reactive oxygen species (ROS) clearance pathways. Here, 28 identified AKR family genes were genome-wide, characteristics,...
Three-dimensional integrated packaging with through-silicon vias (TSV) can meet the requirements of high-speed computation, high-density storage, low power consumption, and compactness. However, higher density increases heat dissipation problems, such as severe internal storage prominent local hot spots. Among bulk materials, diamond has highest thermal conductivity (≥2000 W/mK), thereby prompting its application in high-power semiconductor devices for dissipation. In this paper, we report...
Astaxanthin is a natural carotenoid with strong antioxidant activity. In this paper, the effects of carbon source, corn steep liquor, distiller grains, and initial pH on growth astaxanthin production Phaffia rhodozyma D3 were evaluated. The optimal medium composition was 32 g/L glucose, 12 liquor as nitrogen 6.7. cultured in shake flask under these optimized conditions, biomass 6.47 g/L, astaxanthin/OD475 15.16, content 1.41 mg/g. further increased to 4.70 mg/g by combination TiO2...
Abstract BACKGROUND Astaxanthin is a carotenoid with strong antioxidant property. In addition, it has anti‐cancer, anti‐tumor, anti‐inflammatory and many other functions. The micro‐organisms that mainly produce astaxanthin are Haematococcus pluvialis Phaffia rhodozyma . Compared H , P shorter fermentation cycle easier to control culture conditions, but the yield of in low. This article studied how improve production RESULTS results showed when 10 mL L −1 soybean oil was added medium,...
Utilizing the integration by parts rule, a simple and general computational method is proposed for solving quasi-steady parallel plate flow problems most types of fluids can be handled this method, such as Newtonian fluid, Power-law Bingham Herschel-Bulkley fluid. The rate-pressure gradient relation flows derived based on an abstract piecewise constitutive equation. Moreover, rate directly expressed in terms equation so high efficiency achieved. As application example new magnetorheological...
Abstract Background The phenotypic transition of pulmonary artery smooth muscle cells (PASMCs) is a central pathological alteration in remodeling that contributes to hypertension (PH). specific role long noncoding RNAs (lncRNAs), especially super enhancer (SE)-driven lncRNAs, the transformation PASMCs induced by hypoxia remains unclear. objective this study determine mechanistic enhancer-driven LncRNA UNC5B-AS1 and hypoxia-induced vascular remodeling. Methods lncRNA regulated super-enhancers...
In this paper, the response time of one magnetorheological fluid (MR) damper with maximum damping force 250kN was tested. Experimental results show that, when electric current increase, is about 0.1 to 0.3s; decrease and not zero, 0.2 0.3s, higher change induce longer time. also 0.6 0.7s, which much than expected. Further experiment if subtracting coil, 60 70ms, 140 150ms.