A5047129641- Dendrimers and Hyperbranched Polymers
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Polymer Surface Interaction Studies
- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Metal complexes synthesis and properties
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Computational Drug Discovery Methods
- Antimicrobial agents and applications
- MicroRNA in disease regulation
- Bone Tissue Engineering Materials
- Silk-based biomaterials and applications
- Nanocomposite Films for Food Packaging
- biodegradable polymer synthesis and properties
- Photodynamic Therapy Research Studies
- Nanocluster Synthesis and Applications
Korea Institute of Science and Technology
2018-2025
Korea University of Science and Technology
2019-2025
Korean Association Of Science and Technology Studies
2019-2025
Bio-Medical Science (South Korea)
2019-2025
Sorbonne Université
2025
Inserm
2025
Korea University
2019
Institute of Biophysics and Cell Engineering
2015-2018
Currently, RNAi based approaches for cancer treatment involving short double stranded RNA molecules (siRNA) are under vigorous scrutinization. Due to numerous biological obstacles, siRNA delivery into target cells requires protective escort. On the other hand, combining of siRNA-mediated gene silencing and action conventional chemotherapeutics can propose additional enhancement anticancer activity. In present study, we investigated a cocktail able downregulate anti-apoptotic genes (BCL-xL,...
Coordination of ruthenium arene fragments on carbosilane dendrimers' surface greatly increases their antitumor properties. Newly synthetized dendrimers are water-soluble, monodisperse and stable. Since good carriers drugs genes, the presence in structure makes them promising candidates for new drug delivery systems with improved potential. Carbosilane more toxic to cancer cells than normal cells. Results several vitro studies applied here indicate that induce apoptosis promyelocytic leukemia HL-60
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