A5004241837- Dendrimers and Hyperbranched Polymers
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Protein Interaction Studies and Fluorescence Analysis
- Nanoparticle-Based Drug Delivery
- Nerve injury and regeneration
- Polymer Surface Interaction Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- DNA and Nucleic Acid Chemistry
- Computational Drug Discovery Methods
- Virus-based gene therapy research
- MicroRNA in disease regulation
- Luminescence and Fluorescent Materials
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- HIV Research and Treatment
- Advanced Polymer Synthesis and Characterization
- Advanced Nanomaterials in Catalysis
- Click Chemistry and Applications
- Immunotherapy and Immune Responses
- Neurological Disorders and Treatments
- Metal complexes synthesis and properties
- Protein Structure and Dynamics
- Chemical Synthesis and Analysis
- Lipid Membrane Structure and Behavior
Institute of Biophysics and Cell Engineering
2016-2025
National Academy of Sciences of Belarus
2011-2025
Minsk Institute of Management
2021
University of Łódź
2005-2013
Republican Scientific and Practical Center of Neurology and Neurosurgery
2013
Universidad de Alcalá
2007
Hospital General Universitario Gregorio Marañón
2007
Abstract Dendrimers provide many exciting opportunities for potential biomedical applications. However, owing to their positively charged surfaces, poly(propyleneimine) (PPI) dendrimers show toxic and haemolytic activities. One of the methods masking peripheral cationic groups is modify them using carbohydrate residues. In this study, three types fourth generation PPI dendrimers‐uncoated (PPI‐g4), approximately 35% maltotriose (Mal‐III)‐coated (PPI‐g4‐OS), 90% Mal‐III‐coated (PPI‐g4‐DS) were...
Abstract The application of nanotechnology in biological and medical fields have resulted the creation new devices, supramolecular systems, structures, complexes, composites. Dendrimers are relatively nanotechnological polymers with unique features; they globular shape, a topological structure formed by monomeric subunit branches diverging to sides from central nucleus. This review analyzes main features dendrimers their applications biology medicine regarding cancer treatment. that include...
Research concerning new targeting delivery systems for pharmacologically active molecules and genetic material is of great importance. The aim the present study was to investigate potential fourth generation (P4) cationic phosphorus-containing dendrimers bind fluorescent probe 8-anilino-1-naphthalenesulfonate (ANS), anti-neoplastic drug cisplatin, anti-HIV siRNA siP24 its capability deliver green protein gene (pGFP) into cells. interaction between P4 ANS (as model drug) investigated. binding...