Ashley Duplessis
- SARS-CoV-2 and COVID-19 Research
- Immune responses and vaccinations
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
Heinrich Heine University Düsseldorf
2021
Düsseldorf University Hospital
2021
Abstract Background Tracing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission chains is still a major challenge for public health authorities, when incidental contacts are not recalled or perceived as potential risk contacts. Viral sequencing can address key questions about SARS-CoV-2 evolution and may support reconstruction viral networks by integration molecular epidemiology into classical contact tracing. Methods In collaboration with local we set up an...
Abstract Viral genome sequencing can address key questions about SARS-CoV-2 evolution and viral transmission. Here, we present an integrated system of genomic surveillance in the German city Düsseldorf, combining a) sequencing, b) genetically based identification infection clusters population, c) analysis hospital outbreaks, d) integration public health authority contact tracing data, e) a user-friendly dashboard application as central data platform. The generated (n = 320 genomes) showed...