A5103170506- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Eosinophilic Esophagitis
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Neonatal Respiratory Health Research
- Pediatric health and respiratory diseases
- Autoimmune Bullous Skin Diseases
- Contact Dermatitis and Allergies
- Immunodeficiency and Autoimmune Disorders
- Vitamin K Research Studies
- RNA modifications and cancer
- Identification and Quantification in Food
- Infant Health and Development
- Celiac Disease Research and Management
- Leech Biology and Applications
- Neurogenetic and Muscular Disorders Research
- Child Nutrition and Feeding Issues
- Enzyme function and inhibition
- Congenital Anomalies and Fetal Surgery
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gastrointestinal motility and disorders
University of British Columbia
2015-2024
British Columbia Children's Hospital
2014-2024
Dalhousie University
2022-2023
ENT and Allergy
2022
National Institute of Allergy and Infectious Diseases
2022
Women and Children’s Health Research Institute
2016
University of Alberta
2016
Child and Family Research Institute
2015
BackgroundAlthough oral immunotherapy (OIT) for food allergy is a reasonable treatment option, barriers to this procedure's implementation have not been extensively evaluated from patient perspective.ObjectiveWe the patients face during OIT administration, including anxiety and taste aversion, role of health care professionals, especially dietitians.MethodsA survey in Canada United States involved families currently enrolled programs.ResultsOf responses 379 participants, fear reaction was...
Allergic rhinitis (AR) is a prevalent disease in Canada that affects both children and adults. Several guidelines for the management of AR have been published by professional allergy societies worldwide. However, there are regional differences clinical AR, regulatory approval some pharmacotherapies varies among countries. Thus, six research questions specific to treatment were identified this focused practice parameter. Reviews literature since 2016 conducted obtain evidence-based support...
Abstract Background Current management of food protein-induced enterocolitis syndrome (FPIES) involves strict avoidance the offending for 12–18 months, followed by oral challenge (OFC) under physician supervision. OFCs are resource-intensive and there is a lack universal standardized protocol FPIES. Prolonged may increase risk IgE-mediated allergy, particularly in atopic patients. Food ladders have shown success promoting accelerated tolerance patients with allergy. Our case series evaluated...
COVID-19 vaccination has been associated with anaphylaxis and hypersensitivity reactions. Infectious disease physicians allergists in the Canadian Special Immunization Clinic (SIC) Network developed guidance for evaluating patients adverse events following immunization (AEFI) including suspected hypersensitivity. This study evaluated management event recurrence subsequent vaccinations.
The coronavirus disease 2019 (COVID-19) pandemic has led to the deprioritization of non-emergency services, such as oral food challenges and initiation immunotherapy (OIT) for food-allergic children. Recent studies have suggested that home-based peanut OIT could be a safe effective option low-risk peanut-allergic In period between September 1, 2020, January 31, 2021, nine preschoolers with history mild allergic reactions underwent OIT. Eight them (88.9%) completed build-up phase at home in...
An understanding of how patient characteristics such as age, baseline peanut-specific IgE, and atopic comorbidities may influence potential safety outcomes during peanut oral immunotherapy (P-OIT) could aid in shared decision making between clinicians families.This study explored the relationship reactions P-OIT using a large sample size to better understand risk factors influencing safety.Data were obtained from Food Allergy Immunotherapy (FAIT) registry, which collects real-world OIT data...
Previous studies support the effectiveness of sesame oral immunotherapy (S-OIT) in patients >4 years old using maintenance doses 1200 mg protein. However, tahini is often not palatable to children, and high-maintenance may be possible for preschoolers. We studied safety outcomes preschoolers with allergy who underwent low-dose S-OIT 200 Preschoolers allergy, a history objective reaction sesame, either positive skin prick test result (wheal diameter ≥3 mm) or sesame-specific IgE level ≥0.35...
Abstract Most Canadian food allergy data has focused on Health Canada’s priority allergens. This study describes which non-priority (emerging) allergens were most commonly reported by parents and categorized/confirmed allergists. A secondary aim was to describe severity of allergic reactions emerging Parents experienced their child (< 18 years) occurred in the past 12 months, allergists them according likelihood IgE-mediated allergy. Of 68 eligible patients completing survey,...
Background. In the fall of 2014, a North American outbreak enterovirus D68 resulted in significant number pediatric hospital admissions for respiratory illness throughout America. This study characterized clinical presentation and risk factors severe course children admitted to British Columbia Children's Hospital during 2014 outbreak. Methods. Retrospective chart review patients with confirmed EV-D68 infection BCCH symptoms 2014. Past medical history, presentation, management, was collected...
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KEY POINTS A 23-year-old pregnant woman (gravida 2, abortion/miscarriage 1, para 0) with a history of anxiety (treated citalopram) and cocaine use (stopped before pregnancy) no family swelling presented to hospital at 9 weeks gestation. She reported episodic abdominal pain
Oral immunotherapy (OIT) is an increasingly utilized management strategy for IgE-mediated food allergy. Despite promising efficacy and effectiveness, there still a lack of data surrounding the reasons discontinuation OIT. The primary reason stated in literature adverse gastrointestinal effects. Social factors contributing to OIT have not been well reported. We hypothesize that social considerations are significant contributors treatment discontinuation.