- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Reproductive System and Pregnancy
- COVID-19 and healthcare impacts
- Neonatal Respiratory Health Research
- SARS-CoV-2 and COVID-19 Research
- Porphyrin Metabolism and Disorders
- Medical Imaging and Pathology Studies
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Systemic Lupus Erythematosus Research
- Iron Metabolism and Disorders
- Congenital Diaphragmatic Hernia Studies
- Reproductive Physiology in Livestock
- Folate and B Vitamins Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Monoclonal and Polyclonal Antibodies Research
- Smoking Behavior and Cessation
- Tracheal and airway disorders
- Erythrocyte Function and Pathophysiology
- Infant Nutrition and Health
- Clostridium difficile and Clostridium perfringens research
- Reproductive Biology and Fertility
- Infant Development and Preterm Care
- Antifungal resistance and susceptibility
Universidade da Coruña
2023-2024
Complexo Hospitalario Universitario A Coruña
2018-2023
University of Siena
2021
Hospital Materno-Infantil
2021
Hospital Universitario de Móstoles
2009-2010
Hospital Universitario 12 De Octubre
2000-2005
Research Institute Hospital 12 de Octubre
1999-2005
Hospital Clínico San Carlos
2005
Universidad Complutense de Madrid
2000
The SARS-CoV-2 infection has widely spread to become the greatest public health challenge date, COVID-19 pandemic. Different fatality rates among countries are probably due non-standardized records being carried out by local authorities. Spanish case-fatality rate is 11.22%, far higher than those reported in Asia or other European countries. A multicentre retrospective study of demographic, clinical, laboratory and immunological features 584 hospitalized patients their outcomes was...
Abstract: HLA‐G is expected to play an important role during fetal development. Recently, a healthy individual homozygous for the HLA‐G*0105N allele has been described, suggesting that expression was not essential survival. We now report studies of one family with five siblings , who had normally delivered; three these were females also normal deliveries. In addition, cDNA fully sequenced, and G1 membrane anchored protein cannot be translated since after codon 130 cytosine deletion (exon 3)...
Abstract Background One hundred fifty million contagions, more than 3 deaths and little 1 year of COVID-19 have changed our lives health management systems forever. Ageing is known to be one the significant determinants for severity. Two main reasons underlie this: immunosenescence age correlation with comorbidities such as hypertension or dyslipidaemia. This study has two aims. The first obtain cut-off points laboratory parameters that can help us in clinical decision-making. second analyse...
ABSTRACT Background SARS-CoV-2 infection has widely spread to the hugest public health challenge date, COVID-19 pandemic. Different fatality rates among countries are probably due non-standardized records being carried out by local authorities. Spanish case-fatality rate is 11.94%, far higher those reported in Asia or other European countries. A multicenter retrospective study was performed of demographic, clinical, laboratory and immunological features 574 hospitalized patients their...
Abstract The major histocompatibility complex (MHC)‐F class Ib locus shows a limited polymorphism, and the function of its mainly intracellular protein is not clear. We have identified human leucocyte antigen (HLA)‐F orthologous DNA sequences in Pongidae order to study MHC‐F gene evolution products' function. HLA‐F cDNA transcripts are found chimpanzee new primate species studied (bonobo, gorilla orangutan). Analyses predicted amino acid their comparison with other proteins show that may be...
Abstract Background and Aims: It has been postulated that the HFE C282Y mutation (linked to human leukocyte antigen [HLA]‐A3‐B7 haplotype) is not only responsible for hereditary hemochromatosis; HLA class I alleles would also contribute disease pathogenesis. In addition, H63D linked HLA‐A29‐B44 be pathogenetic, particularly in Mediterranean Basin throughout world. However, sporadic porphyria cutanea tarda (s‐PCT) these mutations. present work, we have studied mutations genes test hypotheses....