Maria C. van Hooff
A5032787060- Liver Diseases and Immunity
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Drug Transport and Resistance Mechanisms
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatitis Pathology and Treatment
- Cancer, Lipids, and Metabolism
Erasmus MC
2021-2024
BackgroundTacrolimus has been associated with recurrence of primary biliary cholangitis (PBC) after liver transplantation (LT), which in turn may reduce survival. This study aimed to assess the relation between type calcineurin inhibitor (CNI) and long-term outcomes following LT patients PBC.MethodsSurvival analyses were used association immunosuppressive drugs graft or patient survival among adult PBC dataset European Liver Transplant Registry. Patients who received a donation brain death...
We aimed to externally validate the performance of RETREAT score in a European population.This single center retrospective cohort study enrolled all consecutive patients with HCC who underwent LT between 1989 and 2019. The was assessed overall population after stratification being within or beyond Milan criteria based on explant pathology report. Recurrence probabilities were estimated by using Kaplan-Meier method compared log-rank test.We studied 203 patients; 42 pathology. median follow-up...
INTRODUCTION: Treatment of primary biliary cholangitis (PBC) can improve the GLOBE score. We aimed to assess association between changes in score (ΔGLOBE) and liver transplantation (LT)–free survival patients with PBC who were treated ursodeoxycholic acid (UDCA). METHODS: Among UDCA-treated within Global cohort, ΔGLOBE (ΔGLOBE 0–1 : during first year UDCA, 1–2 second year) risk LT or death was assessed through Cox regression analyses. RESULTS: Overall, 3,775 included; 3,424 (90.7%) female,...
This study aims to assess the health-related quality of life (HRQoL) in a Dutch population patients with primary biliary cholangitis (PBC) relation prognosis and need for second line-therapy, based on both objective disease parameters patients' perspectives.In this cross-sectional multicenter study, HRQoL was assessed by using PBC-40 according clinical perspectives treatment prognosis.In total, 178/269 (66%) responded; mean age 61.2 (SD 9.9) years 165 (92.7%) women. The domain scores did not...
Introduction: AFP and the RETREAT score are currently used to predict HCC recurrence after LT. However, superior discriminating models needed for low populations. The aim of this study is investigate predictive value PIVKA-II on recurrence-free survival LT in a population microvascular invasion explant. Methods: A retrospective cohort including all consecutive patients transplanted between 1989 2019 Erasmus MC University Medical Center Rotterdam, Netherlands, was used. levels were determined...
Patients with primary biliary cholangitis (PBC) have an impaired health-related quality of life (HRQoL). Practice guidelines recommend evaluating the HRQoL in all patients PBC. The aim this study was to assess reliability and validity our Dutch translation PBC-40, a PBC-specific measure HRQoL.The PBC-40 translated into following standardised forward-backward procedures. Participants received RAND-36 (a validated version 36-Item Short Form Health Survey) through postal mail. PBC-27 is...