A5046461909- Cutaneous Melanoma Detection and Management
- Nonmelanoma Skin Cancer Studies
- Cancer and Skin Lesions
- Cancer Genomics and Diagnostics
- Nail Diseases and Treatments
- Immunotherapy and Immune Responses
- Skin Protection and Aging
- Cutaneous lymphoproliferative disorders research
- Melanoma and MAPK Pathways
- Genetic and rare skin diseases.
- vaccines and immunoinformatics approaches
- Bacterial Genetics and Biotechnology
- Cancer-related Molecular Pathways
- Cancer Risks and Factors
- MicroRNA in disease regulation
- melanin and skin pigmentation
- Autoimmune Bullous Skin Diseases
- Bacteriophages and microbial interactions
- CAR-T cell therapy research
- Dermatological and Skeletal Disorders
- Biocrusts and Microbial Ecology
- Parasitic infections in humans and animals
- Occupational and environmental lung diseases
- Antimicrobial Peptides and Activities
- Yersinia bacterium, plague, ectoparasites research
San Gallicano Hospital
2011-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2004-2025
University of Pisa
2025
Cancer Genetics (United States)
2023
Columbia University
2023
University of Milan
2019
Istituti Fisioterapici Ospitalieri
2016
Institute of Biostructure and Bioimaging
2012
In-Q-Tel
2006
Istituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro
2004
Most dermoscopic algorithms to diagnose melanoma were established more than 10 years ago and have been tested primarily on clear-cut melanomas excised melanocytic naevi.To assess the diagnostic performance of pattern analysis seven-point checklist lesions that reflect current clinical setting, compared with a revised lower threshold for excision.Eight experienced dermatologists viewed images 100 melanomas, naevi monitored naevi. Each lesion was evaluated by scored as naevus, or be excised....
To assess the outcome on management recommendations of a comparative approach vs morphologic in evaluating dermoscopic images lesions from series patients with multiple nevi.In 2-step study, 6 experienced dermoscopists were asked to provide (excision or follow-up) for nevi based lesions. In first step, participating evaluated individual only structure (morphologic approach). second same grouped by patient, allowing participants evaluate context other patient (comparative approach).Academic...
Eccrine poroma can mimic benign and malignant melanocytic non-melanocytic lesions. To date, little is known about the dermoscopic features of this condition. Seven histopathologically proven cases eccrine were examined using dermoscopy by three independent dermatologists. Both glomerular hairpin vessels observed in 71% cases, whereas linear irregular 43% cases. A white-to-pink halo surrounding multiple pink-white structureless areas also frequently found (in 86% respectively). Three...
There is growing interest in the environmental impact of surgical procedures, yet more information needed specifically regarding liver transplantation. This study aims to quantify total greenhouse gas emissions, or carbon footprint, associated with adult whole-size transplantation from donors after brain death, including relevant back-table graft preparation. The footprint was calculated retrospectively using a bottom-up approach. approach sums volumes energy consumption (kWh), volatile...
Pregnancy-associated melanoma affects both maternal and fetal health. This study aims to demonstrate how a specialized center multidisciplinary approach can provide the best outcomes. From January 2006 September 2023, bicentric observational was conducted at Plastic Surgery Department of Policlinico Umberto I, Sapienza University Rome, Regenerative San Gallicano Dermatological Institute IRCCS, Italy. Out 6800 cases, twenty pregnant women were selected: thirteen underwent only wide local...
<i>Background:</i> The dermoscopic patterns of pigmented skin tumors are influenced by the body site. <i>Objective:</i> To evaluate clinical and features associated with vulvar lesions. <i>Methods: </i>Retrospective analysis images χ<sup>2</sup> test was used to association between data histopathological diagnosis. <i>Results:</i> A total 42 (32.8%) melanocytic 86 (67.2%) nonmelanocytic lesions were analyzed. Nevi significantly...
Abstract Background Dermatofibroma is a common skin neoplasm that usually easy to recognize, but in some cases its differentiation from melanoma and other tumours may be difficult. Objective To describe the dermoscopic features of dermatofibromas, with special emphasis on characteristics atypical patterns, calculate pattern frequency according patients age gender, anatomical site histopathological subtype. Methods Two groups were consecutively seen, one dermatofibromas surgically excised...
The occurrence of cancer in pregnant women is not a common phenomenon and the real incidence malignant melanoma during this period unknown. Many authors reported poor prognosis with compared non-pregnant women's tumour. Several retrospective reviews worsened found that progesterone oestrogen receptors can be detected tissue. Other data are conflict these opinions; several studies demonstrated timing disease diagnosis pregnancy did appear to influence risk mortality. In our report, we...
Vulvar melanosis is a benign pigmented lesion that may clinically mimic melanoma. Whereas the dermoscopic features of other skin lesions have been extensively described, little known about vulvar melanosis.A retrospective study was conducted on 87 with histopathologically proved melanosis. We describe and define, for first time to our knowledge, ringlike pattern, found in 28 melanotic (32%), characterized by multiple round oval structures, white tan, dark brown, well-defined regular borders....
Background: Cutaneous melanoma arises from skin melanocytes and has a high risk of metastatic spread. Despite better prevention, earlier detection, the development innovative therapies, incidence mortality increase annually. Major clinical factors for include fair skin, an increased number nevi, presence dysplastic family history melanoma. However, several external inducers seem to be associated with susceptibility such as environmental exposure, primarily unprotected sun experience, alcohol...
BackgroundTacrolimus has been associated with recurrence of primary biliary cholangitis (PBC) after liver transplantation (LT), which in turn may reduce survival. This study aimed to assess the relation between type calcineurin inhibitor (CNI) and long-term outcomes following LT patients PBC.MethodsSurvival analyses were used association immunosuppressive drugs graft or patient survival among adult PBC dataset European Liver Transplant Registry. Patients who received a donation brain death...
Patients with a high total nevus count (TNC) merit total-body examination, but simple strategy to identify these high-risk individuals is essentially missing. The aim of this study was investigate the correlation between number melanocytic nevi on both arms and TNC, evaluate patient variables that may have an effect association. In multicenter, cross-sectional study, 2175 patients were examined mean arm in relation TNC calculated. A value fewer than 10 found lower 51 greater 19 scored 50....
CDKN2A and CDK4 are the only known high-penetrant genes conferring proneness to cutaneous melanoma. The locus consists of four exons encodes several alternate transcripts, two which p16(INK4a) p14(ARF), originate from different open reading frames. Exon 1alpha is specific for p16(INK4a), while exon 1beta characterizes p14(ARF). Most mutations located in 2, variations have been identified rare melanoma-prone pedigrees. In a previous study, we investigated 155 Italian melanoma cases, including...
Basal cell carcinoma (BCC) is the most common cancer affecting Caucasians and, due to its large size or poor condition of patient, it can be difficult treat with conventional therapies: in these cases photodynamic therapy methyl aminolevulinate (MAL-PDT) may represent a good option. A retrospective non-comparative follow-up study was performed test response giant and BCC MAL-PDT. Twelve patients 14 (> = 5 cm) (4-5 were treated MAL-PDT; they evaluated 6 months after end treatment define...