A5102857782- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Lipoproteins and Cardiovascular Health
- Chronic Kidney Disease and Diabetes
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Cardiac Fibrosis and Remodeling
- Vascular Procedures and Complications
- Atrial Fibrillation Management and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutrition and Health in Aging
- Cardiovascular Disease and Adiposity
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Respiratory Support and Mechanisms
- Eicosanoids and Hypertension Pharmacology
- Infectious Aortic and Vascular Conditions
- Cardiac Valve Diseases and Treatments
- Blood properties and coagulation
- Signaling Pathways in Disease
- Cardiac Ischemia and Reperfusion
West China Hospital of Sichuan University
2014-2024
Sichuan University
2014-2024
West China Second University Hospital of Sichuan University
2014
Background. After myocardial infarction, anti-inflammatory macrophages perform key homeostatic functions that facilitate cardiac recovery and remodeling. Several studies have shown lactate may serve as a modifier influences phenotype of macrophage. However, the therapeutic role sodium in infarction (MI) is unclear. Methods. MI was established by permanent ligation left anterior descending coronary artery followed injection saline or lactate. Cardiac function assessed echocardiography. The...
Abstract Stromal cell‐derived factor‐1 (SDF‐1) is a well‐characterized cytokine that protects heart from ischaemic injury. However, the beneficial effects of native SDF‐1, in terms promoting myocardial repair, are limited by its low concentration myocardium. Annexin V (AnxA5) can precisely detect dead cells vivo. As massive cardiomyocytes die after MI, we hypothesize AnxA5 be used as an anchor to carry SDF‐1 In this study, constructed fusion protein consisting and domains. The receptor...
The role of triglyceride (TG) in secondary prevention patients with coronary artery disease (CAD) was debated. In the present study, we assessed association between admission TG levels and long-term mortality risk CAD patients.
Abstract Background A new 4‐tired classification of left ventricular hypertrophy ( LVH ) based on LV concentricity and dilation has been proposed; however, the association between categorization geometry outcomes in patients with coronary artery disease CAD is still unknown. Methods All 2297 included underwent echocardiographic examination prior to discharge. Left mass LVM was calculated, end‐diastolic volume EDV indexed by body surface area BSA ). Study cohort divided into five groups...
We try to analyse the effect of renal functions on death in CAD patients with different body compositions. A retrospective analysis was conducted 2989 consecutive confirmed by coronary angiography were enrolled and grouped into two categories: basically preserved function (PRF) (eGFR ≥60 ml/min) obviously reduced (RRF) <60 ml/min). The influence insufficiency mortality detected every tertile composition, including mass index (BMI), fat (BF) lean (LMI). end points all-cause mortality. mean...
MARCH5 is a critical regulator of mitochondrial dynamics, apoptosis and mitophagy. However, its role in cardiovascular system remains poorly understood. This study aimed to investigate the endothelial cell (ECs) injury involvement Akt/eNOS signalling pathway this process. Rat models myocardial infarction (MI) human cardiac microvascular cells (HCMECs) exposed hypoxia (1% O2 ) were used study. expression was significantly reduced ECs MI hearts hypoxia. Hypoxia inhibited proliferation,...
Premature ovarian failure (POF) appears to be a complex disease entity with several underlying etiopathogenic contributions including the possibility of multiple distinctly different autoimmune mechanisms, in which inflammatory autoimmunity targeted ovarian-specific germline antigens (e.g., zona pellucida proteins or Mater) differentiation/regulatory factors (e.g. inhibin-alpha) were regarded as one most crucial factors. Platelet-activating factor (PAF) and PAF class oxidized phospholipids...
Objectives Although inappropriate left ventricular mass has been associated with clustered cardiac geometric and functional abnormalities, its predictive value in patients coronary artery disease is still unknown. This study examined the association of clinical outcomes angina pectoris normal ejection fraction. Participants methods Consecutive diagnosed whose fraction was were recruited from 2008 to 2012. Inappropriate determined when ratio actual predicted one exceeded 150%. The primary...
The purpose of this study was to discuss the present situation discharge medications in coronary artery disease (CAD) patients with different levels renal function and assess potential impact these on prognosis patient population. A retrospective cohort conducted. From July 2008 Jan 2012, consecutive CAD confirmed by angiography West China Hospital were enrolled grouped into 3 estimated glomerular filtration rate (eGFR) categories: ≥60, 30 60, <30 mL/min/1.73 m2. endpoints all-cause...