A5090008098- Esophageal Cancer Research and Treatment
- Cancer Immunotherapy and Biomarkers
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Mesenchymal stem cell research
- Lung Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Cells and Metastasis
- Colorectal and Anal Carcinomas
- Aquatic Ecosystems and Phytoplankton Dynamics
- Colorectal Cancer Treatments and Studies
- RNA modifications and cancer
- Plant Molecular Biology Research
- Galectins and Cancer Biology
- Hydrogen's biological and therapeutic effects
- Algal biology and biofuel production
- Cancer-related gene regulation
- Liver Disease and Transplantation
- Aldose Reductase and Taurine
- GDF15 and Related Biomarkers
Yangzhou University
2020-2024
Kunming University
2016-2024
Northern Jiangsu People's Hospital
2023
People's Hospital of Yangzhong
2004
Purpose: The present retrospective study aimed to explore the relationship between pancreatitis and pancreatic cancer in population cohort of UK Biobank (UKB) ( https://www.ukbiobank.ac.uk ). Methods: From 500 thousand UKB, according age gender patients with 1:10, matching control without cancer, binary Logistic regression model was used analyze subgroup analyses were identify potential effect modifiers. Results: A total 1538 compared 15 380 controls. In fully adjusted model, had a...
Abstract A growing number of circular RNAs (circRNAs) have been identified and verified in several cancers. However, highly efficient therapeutic methods based on circRNAs lung cancer remain largely unexplored. In the present study, we a novel RNA, hsa_circ_103820, Gene Expression Omnibus (GEO) data. Functionally, overexpression hsa_circ_103820 showed significant inhibitory effects proliferation, migration invasion cells, knockdown played promoting roles. Regarding mechanism, revealed that...
Scope Naringenin (NAR) possesses unique anti‐inflammatory, antiapoptosis effects and various bioactivities; however, its role against radiation‐induced intestinal injury (RIII) remains unclear. This study aims to investigate whether NAR has protective the underlying mechanisms. Methods results C57BL/6J mice are exposed a single dose of 13 Gy X‐ray total abdominal irradiation (TAI), then gavaged with for 7 days. treatment prolongs survival rate, protects crypts villi from damage, alleviates...
Immune checkpoint inhibitors (ICIs) combined with chemotherapy have become the first-line standard treatment for locally advanced or metastatic esophageal squamous cell carcinoma (ESCC). The evidence also demonstrates improved synergistic effects of when delayed administration ICIs. In this study, we conducted a retrospective investigation into efficacy taxol plus platinum (TP) PD-1 ESCC patients.
Purpose: Biliverdin reductase A (BLVRA) is a pleiotropic enzyme that converts biliverdin-IX-alpha into the antioxidant and anti-nitrosative compound, bilirubin-IX-alpha. It related to various diseases, including cancer. overexpressed in many types of cancers promotes cancer development metastasis, but effects BLVRA colorectal have not been researched at present. This study was aimed investigate biliverdin vivo vitro experiments its possible mechanism. Methods: The clinical samples CRC...
The PhiC31 integration system allows for targeted and efficient transgene expression by recognizing pseudo attP sites in mammalian cells integrating the exogenous genes into open chromatin regions of active chromatin. In order to investigate regulatory patterns gene region integration, this study utilized Ubiquitous Chromatin Opening Element (UCOE) activating RNA (saRNA) modulate structure promoter vector. analysed effects DNA methylation nucleosome occupancy changes integrated on levels....
Paris polyphylla var. yunnanensis , a well-known Chinese medicinal herb, shows unique physiological trait characterized by the cyclic opening and closing of its anthers after pollen maturation. The aim this study was to explore implications phenomenon on breeding. RNA sequencing coupled with methylation used scrutinize compare gene expression profiles alterations in seeds during anther closing, along cold exposure. Genes enriched within Kyoto Encyclopedia Genomes (KEGG) pathways were...
1. Willett J, Achenbach S, Pinto FJ, Poppas A, Elkind MSV. The tobacco endgame-eradicating a worsening epidemic. Eur Heart J. 2021;42(32):3044-3048. doi:10.1093/eurheartj/ehab245 CrossRef Google Scholar
Radiation enteritis is the most common and serious complication of abdominal or pelvic radiation therapy. Mesenchymal stem cells (MSCs), as well cell protection agents, inhibit apoptosis promote proliferation injured tissues. 3 human umbilical cords MSCs (UCMSCs) were injected into tail vein peritoneal cavity a rat model enteritis. The temporary protective effect was assessed by identification donor cells, detection cellular immune parameters inflammatory cytokine levels, quantitation...
Abstract In order to explore the role of inorganic and organic nitrogen on physiological process Scenedesmus quadricauda , we studied influence two compounds, ammonium alanine growth, characteristics. Chlorophyll a maximal photochemical quantum yield PSII (Fv/Fm), maximum electron transport rate (ETRmax) Saturating Light intensity (I k ) were measured by Phyto-PAM under concentration 0.5, 1.0, 2.0, 5.0, 10, 20, 50 mg/L. Results indicated that was lowest in 0.5 mg/L mg/L, it highest value 5...
Abstract WWTR1, a gene related to the TGF-β signaling pathway, has been elucidated be involved in oncogenesis multiple studies. There is, however, no research on its link immune infiltration colon cancer. The TCGA database identified which is lowly expressed cancer patients compared normal subjects. Meanwhile, with GEO and database, we produced Kapan-Meier curve, revealed that high WWTR1 expression had poor prognosis. We discovered of was associated clinical stage, pathological T-stage,...
In regard to Gao et al. To the Editor: We read with interest systematic review and network meta-analysis by al.1Gao Z. Huang S. Wang al.Efficacy safety of immunochemotherapy, immunotherapy, chemotherapy, targeted therapy as first-line treatment for advanced metastatic esophageal cancer: a meta-analysis.Lancet Reg Health Western Pac. 2023; 38100841Google Scholar comparing efficacy cancer. Since immune checkpoint inhibitors (ICIs) combined either fluorouracil + cisplatin (fluorouracil-based...
Objectives: This study aimed to systematically evaluate the correlation between cognitive function and brain imaging findings in patients with hepatic encephalopathy (HE). Methods: We searched PubMed, China National Knowledge Infrastructure, Wanfang databases obtain literature on diagnosis of HE via from establishment March 20, 2023. Two researchers independently screened literature, extracted data, evaluated risk bias included studies. RevMan v. 5.3 software was used meta-analysis. Results:...