A5092309810- Medical Imaging and Analysis
- Gut microbiota and health
- Respiratory Support and Mechanisms
- Clostridium difficile and Clostridium perfringens research
- Artificial Intelligence in Healthcare and Education
- Otolaryngology and Infectious Diseases
- Cardiac electrophysiology and arrhythmias
- Pressure Ulcer Prevention and Management
- Cardiovascular Function and Risk Factors
- Nosocomial Infections in ICU
- Pharmaceutical studies and practices
- Pharmacogenetics and Drug Metabolism
- Statistical Methods in Clinical Trials
- Planarian Biology and Electrostimulation
- Spine and Intervertebral Disc Pathology
- Tryptophan and brain disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Innovations in Medical Education
- Diabetic Foot Ulcer Assessment and Management
- Gastrointestinal motility and disorders
- Medical and Biological Sciences
- Mycobacterium research and diagnosis
- Plant and Fungal Interactions Research
- Infectious Diseases and Tuberculosis
Affiliated Hospital of Guizhou Medical University
2023-2025
Guiyang Medical University
2024-2025
Shandong University
2024-2025
Shanghai Jiao Tong University
2022-2024
Guizhou University
2023
Shenzhen Institutes of Advanced Technology
2021
Bacterial infections pose a significant threat to human health. Catalytic antibacterial nanoparticles that generate reactive oxygen species (ROS) are emerging, as promising therapeutic approach in treating bacterial infection by boosting the innate immune defenses. However, interaction between cells and these catalytic remains poorly understood. Here, using rodent models of infection, we test antimicrobial properties ultrasound-responsive piezo-catalytic (piezoNP). We show piezoNPs strongly...
Septic thrombophlebitis of the internal jugular vein (IJV), known as Lemierre’s syndrome, is a rare complication secondary to infections in head and neck. Cholesteatoma middle ear complicated with syndrome rarely observed clinical practice. Currently, treatment controversy centers on whether anticoagulation therapy necessary for IJV distant metastatic emboli induced by syndrome. A 46-year-old female patient cholesteatoma underwent modified radical mastoidectomy tympanoplasty surgery...
Among healthy Chinese subjects, two capsules of dabigatran etexilate were tested for bioequivalence. Fifty subjects recruited each the fasting and postprandial trials in a randomized, two-sequence, open-label, four-cycle, fully replicated trial design single 150 mg dose either test or reference formulation states. The blood concentration at different time points after administration was determined by high-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS). bioequivalence...
Sepsis is a life-threatening multiple-organ injury caused by disordered host immune response to microbial infection. However, the correlation between gut microbiota dysbiosis and indicators remains unexplored. To address this gap in knowledge, we carried out 16 S rDNA sequencing, analyzed clinical fecal samples from children with sepsis (n = 30) control 25), obtained indicators, including T cell subtypes (CD3+, CD3+CD4+, CD3+CD8+, CD4/CD8), NK cells, cytokines (IL-2, IL-4, IL-6, IL-10, TNF-α...
Coronary heart disease (CHD) and atrial fibrillation (AF) exhibit a close relationship, yet the existing body of research predominantly relies on observational study methodologies, posing challenges in establishing causal relationships. The objective our is to investigate linkages between coronary atherosclerosis (CAAs), angina pectoris, myocardial infarction (MI), AF.
The gut microbial composition has been linked to metabolic and autoimmune diseases, including arthritis. However, there is a dearth of knowledge on the bacteriome, mycobiome, virome in patients with gouty arthritis (GA).We conducted comprehensive analysis multi-kingdom microbiome 26 GA 28 healthy controls, using whole-metagenome shotgun sequencing their stool samples.Profound alterations were observed patients. We identified 1,117 differentially abundant bacterial species, 23 fungal 4,115...
<title>Abstract</title> <bold>Purpose:</bold> This study evaluated and compared the clinical support capabilities of ChatGPT-4.0 ChatGPT-4.0-mini in diagnosing treating lumbar disc herniation (LDH) with radiculopathy. <bold>Methods:</bold> Twenty-one questions (across 5 categories) from NASS Clinical Guidelines were input into ChatGPT-4.0-mini. Five orthopedic surgeons assessed their responses using a 5-point Likert scale for accuracy completeness, 7-point safety. Flesch Reading Ease scores...
Purpose The impact of genetic polymorphisms in the ABCB1 and CES1 genes on dabigatran plasma concentrations remains a subject debate, purpose this study was to quantitatively assess effects esters healthy Chinese subjects employed population pharmacokinetic (PopPK) approach. Methods In total, 1,926 (PK) samples from 123 individuals who were given 150 mg orally during fasting state or postprandially analyzed using PopPK model. A two-compartment model with first-order absorption found...
Abstract An integrated course system centered on organs and systems became a mainstream model among the medical schools in China especially those Shanghai Jiao Tong University School of Medicine. International students attended courses independently. Here we will just put focus basic “Molecules, Cells Tissues” for international students. This research mainly focused factors affecting implementation course, including before enrollment after enrollment. The included Chinese language level...
Background: High prevalence and mortality of sepsis have been widely reported in pediatric intensive care units (PICUs) around the world. Till now, there's a lack national epidemiological data Mainland China. We carried out this study to reveal prevalence, therapeutic interventions, clinical outcomes other characteristics PICUs China.Methods: In cross-sectional study, point was conducted on 12 days from December 2018 November 2019 (from 9 AM third Wednesday every month next Thursday) 53...
Abstract Background: Fecal microbiota transplantation (FMT), a procedure in which fecal material is transferred from donor to recipient, has been increasingly used as treatment restore healthy gut microbiota. There substantial difference the composition of between young and aged hosts, but little known about whether age matching FMT recipient affects restoration long-term maintenance. In present investigation, we aimed study establishment resilience transplanted recipients. Results: We...