A5100614499- Respiratory Support and Mechanisms
- Infant Development and Preterm Care
- Neonatal Respiratory Health Research
- Intensive Care Unit Cognitive Disorders
- Congenital Diaphragmatic Hernia Studies
- Anesthesia and Sedative Agents
- Traditional Chinese Medicine Studies
- Systemic Lupus Erythematosus Research
- Anesthesia and Neurotoxicity Research
- Thermal Regulation in Medicine
- Neuroscience of respiration and sleep
- Neonatal and fetal brain pathology
- Pharmacological Effects of Natural Compounds
- Metabolism and Genetic Disorders
- Traditional Chinese Medicine Analysis
- Cardiac Imaging and Diagnostics
- Poisoning and overdose treatments
- Medical Research and Treatments
- Liver Disease and Transplantation
- Mechanical Circulatory Support Devices
- Advanced X-ray and CT Imaging
- Osteoarthritis Treatment and Mechanisms
- Coronary Interventions and Diagnostics
- Neurological Disease Mechanisms and Treatments
- Family and Patient Care in Intensive Care Units
Jilin University
2016-2025
First Hospital of Jilin University
2016-2025
Xiang Yang No.1 People's Hospital
2025
Qilu Hospital of Shandong University
2022-2025
Jinzhou Medical University
2025
Jiangsu University
2013-2024
Affiliated Hospital of Jiangsu University
2024
University of Wollongong
2024
Southwest Medical University
2024
Institute of Geology, China Earthquake Administration
2024
Abstract Hydrogen‐bond organic frameworks (HOFs) with excellent structural and luminescent properties have emerged as a promising material for the construction of fluorescence sensors. However, designing facile, universal high throughput sensor multiplex detection capacity still remains challenging. Herein, one‐component array is constructed that mimics natural gustatory system accurate high‐throughput discrimination identification versatile analytes. HOF single sensing element greatly...
ABSTRACT Pleural effusion is a common respiratory disease worldwide; however, rapid and accurate diagnoses of tuberculosis pleural (TPE) malignancy (MPE) remain challenging. Although extracellular vesicles (EVs) have been confirmed as promising sources biomarkers, little known about the metabolite compositions its subpopulations their roles in diagnosis effusion. Here, we performed metabolomics lipidomics analysis to investigate characteristics two EV derived from by differential...
Nobiletin (NOB) is a flavonoid derived from citrus peel that has potential as an alternative treatment for liver disease. Liver disease primary health concern globally, and there urgent need effective drugs. This review summarizes the pharmacological characteristics of NOB current in vitro vivo studies investigating preventive therapeutic effects on diseases its mechanisms. The findings suggest promising diseases. It improves function, reduces inflammation oxidative stress, remodels gut...
Osteoarthritis (OA) is a degenerative joint disease and major cause of pain disability in older adults. We have previously identified epidermal growth factor receptor (EGFR) signaling as an important regulator cartilage matrix degradation during epiphyseal development. To study its function OA progression, we performed surgical destabilization the medial meniscus (DMM) to induce two mouse models with reduced EGFR activity, one genetic modification (Egfr(Wa5/+) mice) other pharmacological...
Abstract Introduction Multiple studies have shown that diaphragmatic ultrasound can better predict the outcome of weaning in adults. However, there are few focusing on children, leading to a lack sufficient clinical evidence for application children. The purpose this study was investigate predictive value diaphragm outcomes critically ill Methods included 50 cases whose mechanical ventilation (MV) time > 48 h, and all eligibles were divided into either success group ( n = 39) or failure...
Abstract Background Postdischarge immunity and its correlation with clinical features among patients recovered from coronavirus disease 2019(COVID-19) are poorly described. This prospective cross-sectional study explored the inflammatory profiles recovery of COVID-19 at 3 months after hospital discharge. Methods Patients discharged 4 hospitals in Wuhan, asymptomatic (APs) an isolation hotel, uninfected healthy controls (HCs) were recruited. Viral nucleic acid antibody detection, laboratory...
Abstract Squalene is a lipophilic and non‐volatile triterpene with many industrial applications for food, pharmaceuticals, cosmetics. Metabolic engineering focused on optimization of the production pathway suffer from little success in improving titers because limited space cell membrane accommodating product. Extension would be promising approach to overcome storage limitation successful squalene. In this study, Escherichia coli was engineered squalene by overexpression some proteins. The...
Methicillin-resistant Staphylococcus aureus (MRSA) is a refractory pneumonia-causing pathogen due to the antibiotic resistance and characteristics of persisting inside its host cell. Lysostaphin typical bacteriolytic enzyme for degrading bacterial cell walls via hydrolysis pentaglycine cross-links, showing potential combat multidrug-resistant bacteria. However, there are still grand challenges native lysostaphin because poor shelf stability limited bioavailability. To tackle these...
BACKGROUND The International Study Group of Pancreatic Surgery has established the definition and grading system for postpancreatectomy acute pancreatitis (PPAP). There are no machine learning models predicting PPAP following pancreaticoduodenectomy (PD). AIM To explore predictive model PPAP, test its efficacy to guide clinical work. METHODS Clinical data from consecutive patients who underwent PD between 2016 2024 were retrospectively collected. An analysis risk factors was performed,...
ABSTRACT Aims To predict the progression of children with self‐limited epilepsy centrotemporal spikes (SeLECTS) to epileptic encephalopathy spike‐and‐wave activation in sleep (EE‐SWAS). Methods We conducted a retrospective analysis early clinical and electroencephalography (EEG) data. Clinical parameters included demographic epilepsy‐related characteristics. EEG were qualitatively (localization, lateralization, synchrony, non‐Rolandic discharges, nondipole spikes, multiple focal slow‐wave...
Tanshinone IIA is a lipid-soluble pharmacologically active compound extracted from the rhizome of Chinese herb Salvia miltiorrhiza, well-known traditional medicine used for treatment cardiovascular disorders. Previous studies have identified that tanshinone inhibited overexpression miR-1 in hypoxic neonatal cardiomyocytes. This study was designed to examine effects on miR-133 expression under condition. Neonatal rat cardiomyocytes were cultured environment (2% O2+93% N2+5% CO2) at 37°C 24...
Administration of propofol at the time reperfusion has shown to protect heart from ischemia and (I/R) injury. The aim present study was investigate molecular mechanism underling cardioprotective effect against myocardial I/R injury (MIRI) in vivo vitro. Rat induced by ligation left anterior descending (LAD) artery for 30 min followed 2-hr reperfusion. Propofol pretreatment (0.01 mg/g) performed 10 before In vitro MIRI investigated cultured cardiomyocytes H9C2 following hypoxia/reoxygenation...
Climate change and human activities interact to affect the vegetation landscape. We examined interaction of these drivers using multiproxy records, including data on pollen, charcoal, phytoliths, total nitrogen, organic carbon, loss-on-ignition, from a 268-cm sediment profile in Xinjiang, China. By combining with information gained 214 samples surface pollen assemblages north we were able reconstruct late Holocene climate weighted averaging partial least squares regression model. Our results...
Du-Huo-Ji-Sheng-Tang (DHJST) is a traditional Chinese herbal medicine used to treat osteoarthritis. In the present study, therapeutic effect of DHJST on cartilage degradation in rabbit model osteoarthritis was investigated. knee joints rabbits, anterior cruciate ligament transection (ACLT) performed induce experimental At end sixth week, 30 rabbits with ACLT were divided into six groups, control group, group and Osaminethacine (OSA) which followed for another 4 weeks. The other three groups...
Objective: The imaging-guided percutaneous radiofrequency (RF) ablation of adrenal metastases is a relatively new treatment procedure, compared to the more widespread application technique for liver and renal cancers. present study aims evaluate safety efficacy CT-guided RF in cohort patients. Methods: 33 patients with 38 who received between 2012 2015 were retrospectively reviewed. average diameter treated was 3.0 ± 1.6 cm. outcomes, including presence residual tumours, technical success...
Background Glioblastomas (GBMs) represent both the most common and highly malignant primary brain tumors. The subjective visual imaging features from MRI make it challenging to predict overall survival (OS) of GBM. Radiomics can quantify image objectively as an emerging technique. A pragmatic objective method in clinic assess OS is strongly need. Purpose To construct a radiomics nomogram stratify GBM patients into long‐ vs. short‐term survival. Study Type Retrospective. Population...