Li Zeng

ORCID: 0000-0003-0069-1182
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Electrochemical Analysis and Applications
  • Data Mining Algorithms and Applications
  • COVID-19 Clinical Research Studies
  • Lipid Membrane Structure and Behavior
  • Spectroscopy and Quantum Chemical Studies
  • Advanced Photocatalysis Techniques
  • Big Data and Business Intelligence
  • Nanoparticles: synthesis and applications
  • Electrochemical sensors and biosensors
  • Graphene and Nanomaterials Applications
  • 2D Materials and Applications
  • Food Safety and Hygiene
  • Advanced Control Systems Optimization
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Radical Photochemical Reactions
  • SARS-CoV-2 detection and testing
  • User Authentication and Security Systems
  • COVID-19 epidemiological studies
  • Biometric Identification and Security
  • Probabilistic and Robust Engineering Design
  • Fault Detection and Control Systems
  • Cloud Computing and Resource Management
  • Peer-to-Peer Network Technologies
  • Distributed and Parallel Computing Systems

Dongguan University of Technology
2025

China University of Petroleum, Beijing
2025

Qingdao University of Science and Technology
2025

Kunming University
2024

University of Chinese Academy of Sciences
2016-2024

Affiliated Eye Hospital of Wenzhou Medical College
2024

Wenzhou Medical University
2024

Guangxi Medical University
2023-2024

First Affiliated Hospital of GuangXi Medical University
2024

Research Center for Eco-Environmental Sciences
2019-2023

<h3>Importance</h3> Convalescent plasma is a potential therapeutic option for patients with coronavirus disease 2019 (COVID-19), but further data from randomized clinical trials are needed. <h3>Objective</h3> To evaluate the efficacy and adverse effects of convalescent therapy COVID-19. <h3>Design, Setting, Participants</h3> Open-label, multicenter, trial performed in 7 medical centers Wuhan, China, February 14, 2020, to April 1, final follow-up 28, 2020. The included 103 participants...

10.1001/jama.2020.10044 article EN JAMA 2020-06-03

In this article, we first designed and synthesized curcumin-based near-infrared (NIR) fluorescence imaging probes for detecting both soluble insoluble amyloid beta (Aβ) species then an inhibitor that could attenuate cross-linking of Aβ induced by copper. According to our previous results the possible structural stereohindrance compatibility peptide hydrophobic/hydrophilic property Aβ13-20 (HHQKLVFF) fragment, NIR probe CRANAD-58 was synthesized. As expected showed significant changes upon...

10.1021/ja405239v article EN Journal of the American Chemical Society 2013-10-11

Searching frequent patterns in transactional databases is considered as one of the most important data mining problems and Apriori typical algorithms for this task. Developing fast efficient that can handle large volumes becomes a challenging task due to databases. In paper, we implement parallel algorithm based on MapReduce, which framework processing huge datasets certain kinds distributable using number computers (nodes). The experimental results demonstrate proposed scale well...

10.1109/snpd.2012.31 article EN 2012-08-01

Revealing the nature of interaction between graphene oxide (GO) and lipid membrane is a crucial issue but still remains challenging. Here, we describe our recent effort toward this direction by studying GO-induced vibrational changes interfacial water with surface-enhanced infrared absorption (SEIRA) spectroscopy. The experimental results provide evidence that overcoming electrostatic repulsion phosphate group, its hydrogen bonding attraction as well hydrophobic choline group are driving...

10.1021/jacs.5b03803 article EN Journal of the American Chemical Society 2015-07-29

10.1007/s10799-012-0123-z article EN Information Technology and Management 2012-05-08

InfoMetricsFiguresRef. Environmental Science & TechnologyVol 55/Issue 5Article This publication is free to access through this site. Learn More CiteCitationCitation and abstractCitation referencesMore citation options ShareShare onFacebookX (Twitter)WeChatLinkedInRedditEmailJump toExpandCollapse ViewpointFebruary 16, 2021Evidence of Foodborne Transmission the Coronavirus (COVID-19) Animal Products Food Supply ChainClick copy article linkArticle link copied!Ligang HuLigang HuState Key...

10.1021/acs.est.0c06822 article EN other-oa Environmental Science & Technology 2021-02-16

Three hybrid electrochemical protocols, which involve the energy transfer, direct photolysis and N-hydroxyphthalimide catalyst, respectively, are presented for selenylation/cyclization of fragile substrates 3-aza-1,5-dienes with diorganyl diselenides to afford 3-selenomethyl-4-pyrrolin-2-ones. The two electrophotocatalytic reactions indirect electrolysis one both regioselective external-oxidant- transition-metal-free, associated a broad substrate scope high Se-economy, all three methods...

10.1002/chem.202400280 article EN Chemistry - A European Journal 2024-04-23

Business Intelligence (BI) has been viewed as sets of powerful tools and approaches to improving business executive decision-making, operations, increasing the value enterprise. The technology categories BI mainly encompass Data Warehousing, OLAP, Mining. This article reviews concept provides a survey, from comprehensive point view, on technical framework, process, enterprise solutions. In addition, conclusions out possible reasons for difficulties broad deployment BI, proposals constructing...

10.1109/icsmc.2006.385050 article EN 2006-10-01

BackgroundBecause treatment options for coronavirus disease 2019 (COVID-19) are very limited, the use of convalescent plasma has bee explored.Case presentation and treatmentA male centenarian with cough dyspnea 2 months was diagnosed COVID-19. Without effective treatments increased risks antiviral therapy elderly, this patient given plasma. The viral load, complete blood count, inflammatory indicators, vital signs, clinical symptoms were observed before after COVID-19...

10.1016/j.transci.2020.102820 article EN other-oa Transfusion and Apheresis Science 2020-05-21

Abstract The NLRP3 inflammasome plays an important role in protecting the host from infection and aseptic inflammation, its regulatory mechanism is not completely understood. Dysregulation of can cause diverse inflammatory diseases. HECTD3 a E3 ubiquitin ligase HECT family that has been reported to participate autoimmune infectious However, relationship between well studied. Herein, we show blocks interaction NEK7 inhibit assembly activation. In BMDMs, Hectd3 deficiency promotes activation...

10.1038/s41419-024-06473-4 article EN cc-by Cell Death and Disease 2024-01-24

With the potential continuous application of mono- or few-layered black phosphorus (BP) in electronic, photonic, therapeutic, and environmental fields, possible side effects BP on aquatic organisms after release into natural water are great concern. We investigated toxicity unicellular organism, Tetrahymena thermophila. After exposure for 8 h at 10 μg/mL, reproduction T. thermophila significantly decreased by 46.3%. Severe cell membrane cilium damage were observed scanning electron...

10.1021/acs.est.9b05424 article EN Environmental Science & Technology 2019-12-11

Abstract Metastasis is the leading cause of cancer-related death. The interactions between circulating tumor cells and endothelial adhesion molecules in distant organs a key step during extravasation hematogenous metastasis. Surgery common intervention for most primary solid tumors. However, surgical trauma-related systemic inflammation facilitates metastasis by increasing spread to vascular (ECs). Currently, there are no effective interventions prevent Here, we show that HECTD3 deficiency...

10.1038/s41392-022-01057-0 article EN cc-by Signal Transduction and Targeted Therapy 2022-08-03

Catalyst loss is a typical fault that impacts the long-term operation of fluidized catalytic cracking (FCC) in oil refining process. The FCC disengager critical place for separating catalyst from gas. A fast and precise fault-cause judgment vital avoiding failures. In this study, novel method failures with quantitative criteria was established via tree analysis (FTA) method, based on relationship model between flow field signals faults investigated by computational fluid dynamics (CFD). FTA...

10.3390/pr13020464 article EN Processes 2025-02-08

Abstract BACKGROUND Reactive pressure‐swing distillation (RPSD) is an innovative and promising technology for the separation of azeotropic systems, offering high integration efficiency. However, dynamic control RPSD processes presents significant challenges due to complex coupling nonlinearity. This paper investigates practical structures processes, structure was first designed system separating tetrahydrofuran/methanol/water. RESULT Three based on PID were developed existing both with...

10.1002/jctb.7825 article EN Journal of Chemical Technology & Biotechnology 2025-02-07

Black phosphorus (BP) has extensive applications in various fields. The release of BP into aquatic ecosystems and the potential toxic effects on organisms are becoming major concerns. Here, we investigated developmental toxicity few-layered toward zebrafish. We found that could adsorb surface chorion subsequently penetrate within embryo. After exposure embryos to 10 mg/L BP, malformations appeared at 96 hpf, especially heart deformities such as pericardial edema bradycardia, accompanied by...

10.1021/acs.est.0c05724 article EN Environmental Science & Technology 2020-12-24

Due to potential applications of black phosphorus nanosheets (BPNSs) in many fields the near future, toxicological effects BPNSs on environmental organisms is becoming a major concern. Here, we carried out series toxicity tests and discussed underlying toxic mechanisms Chlorella vulgaris (C. vulgaris). After 120-h exposure, at 1 mg/L promoted growth C. vulgaris, while higher concentrations (5 10 mg/L) inhibited its growth. Metabolomic analysis revealed alterations carbohydrates, fatty acids,...

10.1021/acs.estlett.9b00726 article EN Environmental Science & Technology Letters 2019-12-16
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