Sothear Luke
- Cerebrovascular and Carotid Artery Diseases
- Cancer-related molecular mechanisms research
- Intracranial Aneurysms: Treatment and Complications
- Genetic Associations and Epidemiology
- Vascular Malformations Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Neurosurgical Procedures and Complications
- Optical Imaging and Spectroscopy Techniques
- Cancer-related gene regulation
- Peripheral Artery Disease Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Hemodynamic Monitoring and Therapy
- Radiation Dose and Imaging
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Health and Disease Prevention
University of Maryland, Baltimore
2022
VA Maryland Health Care System
2022
Mayo Clinic in Florida
2011-2020
WinnMed
2012-2020
Jacksonville College
2012-2017
Society for Neuroscience
2012
Object Near-infrared spectroscopy (NIRS) offers noninvasive bedside measurement of direct regional cerebral arteriovenous (mixed) brain oxygenation. To validate the accuracy this monitoring technique, authors analyzed statistical correlation NIRS and CT perfusion with respect to blood flow (CBF) measurements. Methods The retrospectively reviewed all cases in which measurements were obtained at a single, academic neurointensive care unit from February 2008 June 2011 was performed same time as...
Current genome-wide association studies of ischemic stroke have focused primarily on late-onset disease. As a complement to these studies, we sought identify the contribution common genetic variants risk early-onset stroke.
IntroductionThe COVID-19 pandemic has presented challenges to managing vascular risk factors with in-person follow-up of patients asymptomatic carotid stenosis enrolled in the CREST2 trial. is comparing intensive medical management alone versus plus revascularization endarterectomy or stenting. We performed a study evaluate feasibility home-based program for testing blood pressure (BP) and low-density lipoprotein (LDL) CREST2.MethodsThis involved 45 at 10 sites The initial were identified by...
Introduction: Outcomes from endovascular procedures are highly dependent on the experience and skill of operating physician. The multi-disciplinary CREST-2 Interventional Management Committee (IMC) was charged with credentialing a cohort skilled interventionists adequate contemporary case volumes. Methods: Applicants were required to submit 25 consecutive cases completed within 5 years as primary operator out total ≥ 50 (≥ 20 for operators completing training). Interventionists not approved...
Abstract Objective To determine the contribution of common genetic variants to risk early onset ischemic stroke (IS). Methods We performed a meta-analysis genome-wide association studies IS, ages 18-59, using individual level data or summary statistics in 16,927 cases and 576,353 non-stroke controls from 48 different across North America, Europe, Asia. further compared effect sizes at our most significant loci between late IS polygenic scores for venous thromboembolism versus later IS....