A5100724996- Silk-based biomaterials and applications
- Magnetic and transport properties of perovskites and related materials
- Nanoplatforms for cancer theranostics
- Electrospun Nanofibers in Biomedical Applications
- Rare-earth and actinide compounds
- Polymer Surface Interaction Studies
- Advanced Materials and Mechanics
- Advanced materials and composites
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Advanced ceramic materials synthesis
- Supramolecular Self-Assembly in Materials
- Surgical Sutures and Adhesives
- Biosensors and Analytical Detection
- Luminescence and Fluorescent Materials
- Biochemical and Structural Characterization
- Adhesion, Friction, and Surface Interactions
- Shape Memory Alloy Transformations
- Advanced Condensed Matter Physics
- Nanocomposite Films for Food Packaging
- Thermal Expansion and Ionic Conductivity
- Magnetic Properties of Alloys
- Advanced Photocatalysis Techniques
- Advanced Sensor and Energy Harvesting Materials
- Polydiacetylene-based materials and applications
East China Normal University
2022-2025
Chinese Academy of Sciences
2010-2024
University of Chinese Academy of Sciences
2019-2024
Shanghai Institute of Organic Chemistry
1997-2024
Xinjiang Institute of Ecology and Geography
2020-2024
Yangzhou University
2023-2024
Shanghai Institute of Ceramics
1999-2024
Institute of Geochemistry
2023
Tsinghua University
2020-2022
Universität Ulm
2020-2022
Abstract The development of biomedical glues is an important, yet challenging task as seemingly mutually exclusive properties need to be combined in one material, i.e. strong adhesion and adaption remodeling processes healing tissue. Here, we report a biocompatible biodegradable protein-based adhesive with high strengths. maximum strength reaches 16.5 ± 2.2 MPa on hard substrates, which comparable that commercial cyanoacrylate superglue higher than other adhesives by at least order...
Abstract Surgical excision is one of the main treatments for malignant tumors. However, high risk tumour recurrence a major challenge. Near‐infrared (NIR)‐light‐induced tumor photothermal therapy has been studied, while its clinical applications are still restricted due to limited therapeutic effects. To address this, here, novel NIR‐light‐responsive and injectable DNA‐mediated upconversion Au nanoparticle hybrid (DNA–UCNP‐Au) hydrogel developed. Due confined concentrated environment induced...
Adhesive hydrogels have been developed for wound healing applications. However, their adhesive performance is impaired dramatically due to high swelling on wet tissues. To tackle this challenge, we fabricated a new type of non-swelling protein underwater and in vivo In soft material, the electrostatic complexation between supercharged polypeptides with oppositely charged surfactants containing 3,4-dihydroxylphenylalanine or azobenzene moieties plays an important role formation ultra-strong...
Magnetic properties and magnetocaloric effects (MCEs) of ternary intermetallic ErFeSi compound have been investigated in detail. It is found that exhibits a second-order magnetic transition from ferromagnetic to paramagnetic states at the Curie temperature TC = 22 K, which quite close liquid hydrogen (20.3 K). A thermomagnetic irreversibility between zero-field-cooling field-cooling curves observed below low field, it attributed narrow domain wall pinning effect. For field change 5 T,...
The magnetic properties and magnetocaloric effect (MCE) of antiferromagnetic HoCuSi compound have been studied. It is found that undergoes a field-induced first order metamagnetic transition from (AFM) to ferromagnetic (FM) states below the Néel temperature (TN). A giant MCE without hysteresis loss observed in around TN. maximal entropy change (−ΔSM) refrigerant capacity are 33.1 J/kgK 385 J/kg, respectively, for field 0–5 T. excellent can result AFM-FM TN increase magnetization caused by...
Abstract Malignant bone tumors are often accompanied by osteolytic destruction and severe pathological fractures. Current therapeutic strategies can largely inhibit tumor proliferation, but the high recurrence rate of related defects remain a significant challenge. This study aims to address these issues developing novel near‐infrared (NIR) light‐responsive mechanically strong hydrogel that offers excellent photothermal therapy fracture repair capabilities. The as‐prepared exhibits good...
Melanoma is the most lethal malignancy in skin cancer and may occur at any site express melanocytes. Due to malignant melanoma's invasion migration nature, conventional therapies make it challenging remove whole tumor tissue while undertaking high risks of recurrence. Regarding emerging targeted immunotherapy, drug resistance low immunotherapeutic activity remain significant challenges. It thus becoming urgently important develop alternative strategies for melanoma therapy. Herein, a novel...
The utility of unfolded structural proteins with diverse sequences offers multiple potentials to create functional biomaterials. However, it is challenging overcome their defects for the development biological fibers a combination high strength and toughness. Herein, robust from recombinant protein consisting resilin supercharged polypeptide are fabricated via wet-spinning approaches. Particularly, highly ordered structures induced by supramolecular complexation significantly improve fiber's...
The inherently tenuous adhesion strength and limited environmental tolerance of supramolecular adhesives severely restrict their application scenarios. It is challenging for the development robust with extreme temperature tolerance. Herein, we report a new type temperature-resistant crown-ether-protein (CEP) adhesive by harnessing synergistic host-guest molecular interactions between engineered crown ether protein building blocks. outputs CEP demonstrate ultrahigh shearing ≈22 MPa over wide...
Abstract The manipulation of internal interactions at the molecular level within biological fibers is particular importance but challenging, severely limiting their tunability in macroscopic performances and applications. It thus becomes imperative to explore new approaches enhance fibers’ stability environmental tolerance impart them with diverse functionalities, such as mechanical recoverability stimulus-triggered responses. Herein, we develop a dynamic imine fiber chemistry (DIFC)...
Abstract Engineered protein fibers are promising biomaterials with diverse applications due to their tunable structure and outstanding mechanical properties. However, it remains challenging at the molecular level achieve satisfied properties environmental tolerance simultaneously, especially under extreme acid conditions. Herein, construction of artificial comprising chimeric proteins made rigid amyloid peptide flexible cationic elastin‐like (ELP) module is reported. The readily assembles...
Intermetallic compound ErGa exhibits two successive magnetic transitions: spin-reorientation transition at TSR=15 K and ferromagnetic-paramagnetic TC=30 K. Both transitions contribute greatly to the entropy change (ΔSM), each yielding a significant peak on their ΔSM-T curve thus considerable value of refrigerant capacity (RC) without hysteresis loss. For field 5 T, maximal values −ΔSM are 21.3 J/kg TC 16.5 TSR, with an RC 494 J/kg. Large reversible magnetocaloric effect indicate potentiality...
Magnetic properties and magnetocaloric effect (MCE) of intermetallic RFeSi (R = Tb Dy) compounds have been investigated systematically. The undergo a second-order magnetic transition from ferromagnetic to paramagnetic states with the variation temperature. Curie temperatures determined magnetization measurements are 110 K 70 for TbFeSi DyFeSi, respectively, which quite close liquefaction natural gas (111 K) nitrogen (77 K). Both exhibit nearly same large MCE around their respective ordering...
Abstract Fluorescent proteins are investigated extensively as markers for the imaging of cells and tissues that treated by gene transfection. However, limited transfection efficiency lack targeting restrict clinical application this method rooted in challenging development robust fluorescent vivo bioimaging. To address this, a new type near‐infrared (NIR) protein assemblies manufactured genetic engineering is presented. Due to formation well‐defined nanoparticles spectral operation within...
Silk-protein-based fibers have attracted considerable interest due to their low weight and extraordinary mechanical properties. Most studies on fibrous proteins focus the recombinant spidroins, but these exhibit moderate performance. Thus, development of alternative structural for construction robust is an attractive goal. Herein, we report a class biological produced using designed chimeric protein, which consists sequences cationic elastin-like polypeptide squid ring teeth protein....
Abstract Lightweight and mechanically strong protein fibers are promising for many technical applications. Despite the widespread investigation of biological based on spider silk silkworm proteins, it remains a challenge to develop low‐cost proteins convenient spinning technology fabrication robust fibers. Since there plenty widely available in nature, is meaningful investigate preparation by explore their biomedical Here, facile microfluidic strategy developed scalable construction via...
Lightweight and mechanically strong natural silk fibers have been extensively investigated over the past decades. Inspired by this research, many artificial spinning techniques (wet spinning, dry electrospinning, etc.) developed to fabricate robust protein fibers. As traditional methods provide poor control as-spun fibers, microfluidics has integrated with these allow fabrication of biological in a well-designed manner, simplicity cost efficiency. The mechanical behavior can be precisely...